valproic acid has been researched along with Common Migraine in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients presenting with moderate to severe intensity migraine without aura were randomized to receive either 400 mg of iVPA or 10 mg intramuscular metoclopramide + 6 mg SQ sumatriptan (30 patients in each study arm)." | 5.17 | A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache. ( Bakhshayesh, B; Hatamian, H; Hossieninezhad, M; Rezania, K; Seyed Saadat, SM, 2013) |
| " He was diagnosed as having migraine without aura and successfully treated with valproic acid." | 3.79 | Lower back pain as a symptom of migrainous corpalgia. ( Hino-Fukuyo, N; Kakisaka, Y; Katayama, S; Kure, S; Ohara, T; Suzuki, T; Uematsu, M, 2013) |
| " The mean average dosage of valproic acid was 1,250 mg daily." | 2.69 | Valproic acid in prophylaxis of refractory migraine. ( Erdemoglu, AK; Ozbakir, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kakisaka, Y | 1 |
| Ohara, T | 1 |
| Katayama, S | 1 |
| Suzuki, T | 1 |
| Hino-Fukuyo, N | 1 |
| Uematsu, M | 1 |
| Kure, S | 1 |
| Facco, E | 1 |
| Liguori, A | 1 |
| Petti, F | 1 |
| Fauci, AJ | 1 |
| Cavallin, F | 1 |
| Zanette, G | 1 |
| Bakhshayesh, B | 1 |
| Seyed Saadat, SM | 1 |
| Rezania, K | 1 |
| Hatamian, H | 1 |
| Hossieninezhad, M | 1 |
| Tvedskov, JF | 1 |
| Thomsen, LL | 1 |
| Iversen, HK | 1 |
| Gibson, A | 1 |
| Wiliams, P | 1 |
| Olesen, J | 1 |
| Maggioni, F | 1 |
| Ruffatti, S | 1 |
| Dainese, F | 1 |
| Mainardi, F | 1 |
| Zanchin, G | 1 |
| Thomaides, T | 1 |
| Karapanayiotides, T | 1 |
| Kerezoudi, E | 1 |
| Avramidis, T | 1 |
| Haeropoulos, C | 1 |
| Zoukos, Y | 1 |
| Spantideas, A | 1 |
| Erdemoglu, AK | 1 |
| Ozbakir, S | 1 |
5 trials available for valproic acid and Common Migraine
| Article | Year |
|---|---|
Acupuncture versus valproic acid in the prophylaxis of migraine without aura: a prospective controlled study.
Topics: Acupuncture Therapy; Adult; Anticonvulsants; Female; Humans; Male; Migraine without Aura; Pain Measu | 2013 |
A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache.
Topics: Acute Disease; Adult; Analgesics; Dopamine Antagonists; Drug Therapy, Combination; Female; GABA Agen | 2013 |
The prophylactic effect of valproate on glyceryltrinitrate induced migraine.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle A | 2004 |
Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up.
Topics: Adrenergic beta-Antagonists; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants | 2005 |
Valproic acid in prophylaxis of refractory migraine.
Topics: Adult; Female; GABA Agents; Humans; Male; Middle Aged; Migraine without Aura; Recurrence; Severity o | 2000 |
2 other studies available for valproic acid and Common Migraine
| Article | Year |
|---|---|
Lower back pain as a symptom of migrainous corpalgia.
Topics: Adolescent; Anticonvulsants; Brain; Diagnosis, Differential; Electroencephalography; Humans; Low Bac | 2013 |
Intravenous valproate aborts glyceryl trinitrate-induced migraine attacks: a clinical and quantitative EEG study.
Topics: Adult; Electroencephalography; Female; Humans; Infusions, Intravenous; Male; Migraine without Aura; | 2008 |