valproic acid has been researched along with Combat Disorders in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Combat Disorders: Neurotic reactions to unusual, severe, or overwhelming military stress.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been suggested that the anticonvulsant drug pregabalin may be useful in some anxiety disorders." | 5.19 | Effect of pregabalin augmentation in treatment of patients with combat-related chronic posttraumatic stress disorder: a randomized controlled trial. ( Baniasadi, M; Fayyazi Bordbar, MR; Hosseini, G; Mostafavi Toroghi, H; Rezaei Ardani, A, 2014) |
| "Posttraumatic stress disorder (PTSD) is one of the chronic and disabling psychiatric disorders, particularly in combat veterans." | 2.84 | Effect of Rivastigmine Augmentation in Treatment of Male Patients With Combat-Related Chronic Posttraumatic Stress Disorder: A Randomized Controlled Trial. ( Fayyazi Bordbar, MR; Hosseini, G; Mostafavi Toroghi, H; Rezaei Ardani, A; Talaei, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baniasadi, M | 1 |
| Hosseini, G | 2 |
| Fayyazi Bordbar, MR | 2 |
| Rezaei Ardani, A | 2 |
| Mostafavi Toroghi, H | 2 |
| Talaei, A | 1 |
| Davis, LL | 2 |
| Davidson, JR | 1 |
| Ward, LC | 1 |
| Bartolucci, A | 1 |
| Bowden, CL | 1 |
| Petty, F | 2 |
| Nugent, AL | 1 |
| Kramer, GL | 1 |
| Teten, A | 1 |
| Schmitt, A | 1 |
| Stone, RC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD[NCT02884908] | Phase 3 | 252 participants (Anticipated) | Interventional | 2016-09-30 | Active, not recruiting | ||
| Divalproex Sodium in the Treatment of PTSD: A Placebo-Controlled Study[NCT00108576] | Phase 3 | 101 participants (Actual) | Interventional | 2003-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for valproic acid and Combat Disorders
| Article | Year |
|---|---|
Effect of pregabalin augmentation in treatment of patients with combat-related chronic posttraumatic stress disorder: a randomized controlled trial.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Anxiety; Combat Disorders; Depression; Double-Blind M | 2014 |
Effect of Rivastigmine Augmentation in Treatment of Male Patients With Combat-Related Chronic Posttraumatic Stress Disorder: A Randomized Controlled Trial.
Topics: Adult; Cholinesterase Inhibitors; Chronic Disease; Combat Disorders; Double-Blind Method; Drug Syner | 2017 |
Divalproex in the treatment of posttraumatic stress disorder: a randomized, double-blind, placebo-controlled trial in a veteran population.
Topics: Chronic Disease; Combat Disorders; Delayed-Action Preparations; Double-Blind Method; Female; GABA Ag | 2008 |
1 other study available for valproic acid and Combat Disorders
| Article | Year |
|---|---|
Valproate therapy for chronic, combat-induced posttraumatic stress disorder.
Topics: Adult; Arousal; Chronic Disease; Combat Disorders; Humans; Male; Middle Aged; Personality Inventory; | 2002 |