valproic acid has been researched along with Clasp-Knife Spasticity in 8 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Selected examples from three series of isomeric (alkylthio)-1,2,4-triazoles were prepared and examined for anticonvulsant activity versus strychnine-, maximal-electroshock-, pentylenetetrazole-, and 3-mercaptopropionic-acid-induced seizures in mice." | 3.69 | 5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents. ( Dalton, CR; Dudley, MW; Kane, JM; Kehne, JH; Ketteler, HJ; McCloskey, TC; Miller, FP; Ogden, AM; Senyah, Y; Staeger, MA, 1994) |
| "Treatment with valproic acid greatly diminished the frequency of myoclonic jerks with minimal side effects." | 1.30 | Spinal myoclonus complicating spasticity in spinal cord injury: a case study. ( Andary, MT; Green, DF; Hulce, VD; Pysh, JJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kane, JM | 1 |
| Staeger, MA | 1 |
| Dalton, CR | 1 |
| Miller, FP | 1 |
| Dudley, MW | 1 |
| Ogden, AM | 1 |
| Kehne, JH | 1 |
| Ketteler, HJ | 1 |
| McCloskey, TC | 1 |
| Senyah, Y | 1 |
| Rüegg, SJ | 1 |
| Steck, AJ | 1 |
| Fuhr, P | 1 |
| Sandyk, R | 1 |
| Zachariah, SB | 1 |
| Borges, EF | 1 |
| Varghese, R | 1 |
| Cruz, AR | 1 |
| Ross, GS | 1 |
| Andary, MT | 1 |
| Green, DF | 1 |
| Hulce, VD | 1 |
| Pysh, JJ | 1 |
| Finke, J | 1 |
| Gerstenbrand, F | 1 |
| Harrer-Kuhnert, G | 1 |
| Mamoli, G | 1 |
| Watanabe, K | 1 |
1 review available for valproic acid and Clasp-Knife Spasticity
| Article | Year |
|---|---|
[The stiff-man syndrome].
Topics: Baclofen; Diazepam; Humans; Muscle Rigidity; Muscle Spasticity; Syndrome; Valproic Acid | 1987 |
7 other studies available for valproic acid and Clasp-Knife Spasticity
| Article | Year |
|---|---|
5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.
Topics: Animals; Anticonvulsants; Cerebellum; Cerebral Cortex; Chlorides; Electroshock; Flumazenil; Male; Mi | 1994 |
Levetiracetam improves paroxysmal symptoms in a patient with stiff-person syndrome.
Topics: Female; GABA Agonists; Humans; Immunoglobulins, Intravenous; Levetiracetam; Middle Aged; Muscle Spas | 2004 |
Treatment of writer's cramp with sodium valproate and baclofen. A case report.
Topics: Adult; Baclofen; Drug Therapy, Combination; Handwriting; Humans; Male; Muscle Spasticity; Valproic A | 1983 |
Positive response to oral divalproex sodium (Depakote) in patients with spasticity and pain.
Topics: Adult; Humans; Male; Middle Aged; Muscle Spasticity; Pain; Valproic Acid | 1994 |
Spinal myoclonus complicating spasticity in spinal cord injury: a case study.
Topics: Activities of Daily Living; Adult; Anticonvulsants; Drug Therapy, Combination; Electroencephalograph | 1997 |
[Therapy of spasticity using sodium valproinate].
Topics: Humans; Muscle Spasticity; Valproic Acid | 1978 |
[Augmented indication field for Convulex therapy (author's transl)].
Topics: Adolescent; Adult; Aged; Cerebrovascular Disorders; Child, Preschool; Electroencephalography; Enceph | 1976 |