Page last updated: 2024-10-26

valproic acid and Chronic Lung Injury

valproic acid has been researched along with Chronic Lung Injury in 4 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Valproic acid (VPA) has been associated with improved outcomes in multiple models of trauma, when combined with isotonic fluid resuscitation."1.46Lung Protective Effects of Low-Volume Resuscitation and Pharmacologic Treatment of Swine Subjected to Polytrauma and Hemorrhagic Shock. ( Alam, HB; Dennahy, IS; Duan, X; Duggan, MJ; Georgoff, PE; Li, Y; Liu, B; Mesar, T; Nikolian, VC; Pan, B; Wu, X, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Bayrak, BB1
Yilmaz, S1
Hacihasanoglu Cakmak, N1
Yanardag, R1
Nikolian, VC1
Pan, B1
Mesar, T1
Dennahy, IS1
Georgoff, PE1
Duan, X1
Liu, B1
Wu, X1
Duggan, MJ1
Alam, HB1
Li, Y1
Cetinkaya, M1
Cansev, M1
Cekmez, F1
Tayman, C1
Canpolat, FE1
Kafa, IM1
Yaylagul, EO1
Kramer, BW1
Sarici, SU1
Shang, Y1
Jiang, YX1
Ding, ZJ1
Shen, AL1
Xu, SP1
Yuan, SY1
Yao, SL1

Other Studies

4 other studies available for valproic acid and Chronic Lung Injury

ArticleYear
The effects of edaravone, a free-radical scavenger in lung injury induced by valproic acid demonstrated via different biochemical parameters.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:9

    Topics: Animals; Edaravone; Free Radical Scavengers; Lung; Lung Injury; Male; Oxidoreductases; Rats; Rats, S

2021
Lung Protective Effects of Low-Volume Resuscitation and Pharmacologic Treatment of Swine Subjected to Polytrauma and Hemorrhagic Shock.
    Inflammation, 2017, Volume: 40, Issue:4

    Topics: Animals; Caveolin 1; Cells, Cultured; Female; Human Umbilical Vein Endothelial Cells; Humans; Lung I

2017
Protective Effects of Valproic Acid, a Histone Deacetylase Inhibitor, against Hyperoxic Lung Injury in a Neonatal Rat Model.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Biomarkers; Body Weight; Caspase 3; Disease Models, Animal; Histone Deacetylase Inhibitors;

2015
Valproic acid attenuates the multiple-organ dysfunction in a rat model of septic shock.
    Chinese medical journal, 2010, Volume: 123, Issue:19

    Topics: Acute Kidney Injury; Animals; Blotting, Western; Chemical and Drug Induced Liver Injury; Lung Injury

2010