valproic acid has been researched along with Chromosome Inversion in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chromosome Inversion: An aberration in which a chromosomal segment is deleted and reinserted in the same place but turned 180 degrees from its original orientation, so that the gene sequence for the segment is reversed with respect to that of the rest of the chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, he was found to have hyperammonemia within 2 weeks after the addition of low-dose topiramate to valproate." | 7.73 | Topiramate-valproate-induced hyperammonemic encephalopathy syndrome: case report. ( Cheung, E; Fung, CW; Wong, V, 2005) |
| " However, he was found to have hyperammonemia within 2 weeks after the addition of low-dose topiramate to valproate." | 3.73 | Topiramate-valproate-induced hyperammonemic encephalopathy syndrome: case report. ( Cheung, E; Fung, CW; Wong, V, 2005) |
| "A 25-year-old girl with mild mental retardation had a 6-year history of absence seizures, with occasional head drop." | 1.31 | Mild generalized epilepsy and developmental disorder associated with large inv dup(15). ( Canevini, MP; Canger, R; Cavani, S; Chifari, R; Elia, M; Guerrini, R; Pierluigi, M; Sgrò, V, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chifari, R | 1 |
| Guerrini, R | 1 |
| Pierluigi, M | 1 |
| Cavani, S | 1 |
| Sgrò, V | 1 |
| Elia, M | 1 |
| Canger, R | 1 |
| Canevini, MP | 1 |
| Cheung, E | 1 |
| Wong, V | 1 |
| Fung, CW | 1 |
2 other studies available for valproic acid and Chromosome Inversion
| Article | Year |
|---|---|
Mild generalized epilepsy and developmental disorder associated with large inv dup(15).
Topics: Adult; Age of Onset; Angelman Syndrome; Anticonvulsants; Chromosome Aberrations; Chromosome Inversio | 2002 |
Topiramate-valproate-induced hyperammonemic encephalopathy syndrome: case report.
Topics: Adolescent; Anticonvulsants; Brain Diseases; Chromosome Inversion; Chromosomes, Human, Pair 15; Drug | 2005 |