valproic acid has been researched along with Chromosome Deletion in 11 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chromosome Deletion: Actual loss of portion of a chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epilepsy was controlled with valproate at the age of 6 years." | 2.42 | A study of EEG and epilepsy profile in Wolf-Hirschhorn syndrome and considerations regarding its correlation with other chromosomal disorders. ( Fiore, LA; Freitas, A; Kim, CA; Valente, KD, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, S | 1 |
| Hamel, JF | 1 |
| Toma, A | 1 |
| Kelaidi, C | 1 |
| Thépot, S | 1 |
| Campelo, MD | 1 |
| Santini, V | 1 |
| Sekeres, MA | 1 |
| Balleari, E | 1 |
| Kaivers, J | 1 |
| Sapena, R | 1 |
| Götze, K | 1 |
| Müller-Thomas, C | 1 |
| Beyne-Rauzy, O | 1 |
| Stamatoullas, A | 1 |
| Kotsianidis, I | 1 |
| Komrokji, R | 1 |
| Steensma, DP | 1 |
| Fensterl, J | 1 |
| Roboz, GJ | 1 |
| Bernal, T | 1 |
| Ramos, F | 1 |
| Calabuig, M | 1 |
| Guerci-Bresler, A | 1 |
| Bordessoule, D | 1 |
| Cony-Makhoul, P | 1 |
| Cheze, S | 1 |
| Wattel, E | 1 |
| Rose, C | 1 |
| Vey, N | 1 |
| Gioia, D | 1 |
| Ferrero, D | 1 |
| Gaidano, G | 1 |
| Cametti, G | 1 |
| Pane, F | 1 |
| Sanna, A | 1 |
| Germing, U | 1 |
| Sanz, GF | 1 |
| Dreyfus, F | 1 |
| Fenaux, P | 1 |
| Arora, V | 1 |
| Joshi, A | 1 |
| Lall, M | 1 |
| Agarwal, S | 1 |
| Bijarnia Mahay, S | 1 |
| Dua Puri, R | 1 |
| Chander Verma, I | 1 |
| Fernandes, S | 1 |
| Vinnakota, R | 1 |
| Kumar, J | 1 |
| Kale, V | 1 |
| Limaye, L | 1 |
| Cao, Z | 1 |
| Yu, R | 1 |
| Dun, K | 1 |
| Burke, J | 1 |
| Caplin, N | 1 |
| Greenaway, T | 1 |
| Valente, KD | 1 |
| Freitas, A | 1 |
| Fiore, LA | 1 |
| Kim, CA | 1 |
| Toomes, M | 1 |
| Maleck, WH | 1 |
| Koetter, KP | 1 |
| Petroianu, GA | 1 |
| Ritter, M | 1 |
| Kattmann, D | 1 |
| Teichler, S | 1 |
| Hartmann, O | 1 |
| Samuelsson, MK | 1 |
| Burchert, A | 1 |
| Bach, JP | 1 |
| Kim, TD | 1 |
| Berwanger, B | 1 |
| Thiede, C | 1 |
| Jäger, R | 1 |
| Ehninger, G | 1 |
| Schäfer, H | 1 |
| Ueki, N | 1 |
| Hayman, MJ | 1 |
| Eilers, M | 1 |
| Neubauer, A | 1 |
| Martin, A | 1 |
| State, M | 1 |
| Koenig, K | 1 |
| Schultz, R | 1 |
| Dykens, EM | 1 |
| Cassidy, SB | 1 |
| Leckman, JF | 1 |
| Alla, P | 1 |
| Philip, N | 1 |
| Azulay, JP | 1 |
| Attarian, S | 1 |
| Pouget, J | 1 |
| Hellings, JA | 1 |
| Hossain, S | 1 |
| Martin, JK | 1 |
| Baratang, RR | 1 |
| Ikonen, E | 1 |
| Salo, A | 1 |
| Somer, M | 1 |
| Somer, H | 1 |
| Pääkkönen, L | 1 |
| Peltonen, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Integrated European Platform to Conduct Translational Studies in Myelodysplastic Syndromes Based on the EuroBloodNet Infrastructure[NCT04174547] | 8,670 participants (Anticipated) | Observational | 2019-09-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for valproic acid and Chromosome Deletion
| Article | Year |
|---|---|
A study of EEG and epilepsy profile in Wolf-Hirschhorn syndrome and considerations regarding its correlation with other chromosomal disorders.
Topics: Angelman Syndrome; Anticonvulsants; Child; Chromosome Deletion; Chromosome Disorders; Chromosomes, H | 2003 |
Psychopathology, GABA, and the Rubinstein-Taybi syndrome: a review and case study.
Topics: Adult; Chromosome Deletion; Chromosomes, Human, Pair 16; Female; GABA Agonists; Humans; Mental Disor | 2002 |
9 other studies available for valproic acid and Chromosome Deletion
| Article | Year |
|---|---|
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; | 2017 |
Fetal valproate syndrome as a phenocopy of Kleefstra syndrome.
Topics: Abnormalities, Drug-Induced; Adult; Child, Preschool; Chromosome Deletion; Chromosomes, Human, Pair | 2018 |
Improved neural differentiation of normal and abnormal induced pluripotent stem cell lines in the presence of valproic acid.
Topics: Cell Differentiation; Cell Line; Cell Lineage; Cellular Reprogramming; Chromosome Deletion; Dopamine | 2019 |
22q11.2 deletion presenting with severe hypocalcaemia, seizure and basal ganglia calcification in an adult man.
Topics: Adult; Age of Onset; Anticonvulsants; Basal Ganglia; Brain; Calcinosis; Chromosome Deletion; Chromos | 2011 |
Out-of-hospital management of benzodiazepine-resistant status epilepticus in a child with Wolf-Hirschhorn syndrome.
Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Child; Chromosome Deletion; Chromosomes, Human, Pai | 2003 |
Inhibition of retinoic acid receptor signaling by Ski in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Chromosome Deletion; Chromosomes, Human, | 2006 |
Prader-Willi syndrome.
Topics: Child; Chromosome Deletion; Female; Fluvoxamine; Human Growth Hormone; Humans; In Situ Hybridization | 1998 |
[Epilepsy in an adult with chromosome 22q11 micro-deletion].
Topics: Adult; Anticonvulsants; Atrophy; Brain; Chromosome Deletion; Chromosomes, Human, Pair 22; DiGeorge S | 1999 |
Terminal deletion of chromosome 4p (4p16.3) shows a breakpoint between loci linked to Huntington disease.
Topics: Abnormalities, Multiple; Adolescent; Chromosome Banding; Chromosome Deletion; Chromosomes, Human, Pa | 1992 |