valproic acid has been researched along with Chagas Disease in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Triatoma infestans, a vector of Chagas' disease, shows several particular cell biology characteristics, including the presence of conspicuous heterochromatic bodies (chromocenters) where DNA methylation has not been previously detected." | 1.43 | Histone epigenetic marks in heterochromatin and euchromatin of the Chagas' disease vector, Triatoma infestans. ( Alvarenga, EM; Felisbino, MB; Mello, ML; Mondin, M; Moraes, AS; Naves, LS; Rodrigues, VL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarenga, EM | 1 |
| Rodrigues, VL | 1 |
| Moraes, AS | 1 |
| Naves, LS | 1 |
| Mondin, M | 1 |
| Felisbino, MB | 1 |
| Mello, ML | 1 |
1 other study available for valproic acid and Chagas Disease
| Article | Year |
|---|---|
Histone epigenetic marks in heterochromatin and euchromatin of the Chagas' disease vector, Triatoma infestans.
Topics: Animals; Chagas Disease; Chromatin Assembly and Disassembly; Chromosomes, Insect; Disease Vectors; E | 2016 |