valproic acid and Catatonic Rigidity studies

valproic acid and Catatonic Rigidity

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

Excerpt	Relevance	Reference
"We applied valproic acid (VPA) on the rigidity of three parkinsonian patients, two with Parkinson disease and one with striatonigral degeneration."	3.70	[Valproic acid relieved marked rigidity in three patients with end-stage parkinsonism]. ( Fujimoto, K; Nakano, I; Sayama, S, 1998)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (75.00)	18.7374
1990's	1 (25.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

3 (75.00)

18.7374

1990's

1 (25.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Spehlmann, R	1
Norcross, K	1
Rasmus, SC	1
Schlageter, NL	1
Seghieri, G	1
De Giorgio, LA	1
Innocenti, F	1
Pettiná, G	1
Zolfanelli, F	1
Apicella, P	1
Sayama, S	1
Fujimoto, K	1
Nakano, I	1
Watanabe, K	1

Studies

Spehlmann, R

Norcross, K

Rasmus, SC

Schlageter, NL

Seghieri, G

De Giorgio, LA

Innocenti, F

Pettiná, G

Zolfanelli, F

Apicella, P

Sayama, S

Fujimoto, K

Nakano, I

Watanabe, K

Reviews

1 review available for valproic acid and Catatonic Rigidity

Article	Year
[The stiff-man syndrome]. Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:2 Topics: Baclofen; Diazepam; Humans; Muscle Rigidity; Muscle Spasticity; Syndrome; Valproic Acid	1987

Article

Year

[The stiff-man syndrome].

Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:2

Topics: Baclofen; Diazepam; Humans; Muscle Rigidity; Muscle Spasticity; Syndrome; Valproic Acid

1987

Other Studies

3 other studies available for valproic acid and Catatonic Rigidity

Article	Year
Improvement of stiff-man syndrome with sodium valproate. Neurology, 1981, Volume: 31, Issue:9 Topics: Humans; Male; Middle Aged; Muscle Rigidity; Syndrome; Valproic Acid	1981
[Description of a case of a syndrome similar to Reye's syndrome in a male adult undergoing treatment with valproic acid and phenobarbital]. Giornale di clinica medica, 1982, Volume: 63, Issue:9 Topics: Adult; Brain Diseases; Coma; Epilepsy, Tonic-Clonic; Fever; Humans; Male; Muscle Rigidity; Phenobarb	1982
[Valproic acid relieved marked rigidity in three patients with end-stage parkinsonism]. Rinsho shinkeigaku = Clinical neurology, 1998, Volume: 38, Issue:6 Topics: Aged; Female; GABA Agents; Humans; Middle Aged; Muscle Rigidity; Parkinson Disease; Treatment Outcom	1998

Article

Year

Improvement of stiff-man syndrome with sodium valproate.

Neurology, 1981, Volume: 31, Issue:9

Topics: Humans; Male; Middle Aged; Muscle Rigidity; Syndrome; Valproic Acid

1981

[Description of a case of a syndrome similar to Reye's syndrome in a male adult undergoing treatment with valproic acid and phenobarbital].

Giornale di clinica medica, 1982, Volume: 63, Issue:9

Topics: Adult; Brain Diseases; Coma; Epilepsy, Tonic-Clonic; Fever; Humans; Male; Muscle Rigidity; Phenobarb

1982

[Valproic acid relieved marked rigidity in three patients with end-stage parkinsonism].

Rinsho shinkeigaku = Clinical neurology, 1998, Volume: 38, Issue:6

Topics: Aged; Female; GABA Agents; Humans; Middle Aged; Muscle Rigidity; Parkinson Disease; Treatment Outcom

1998