valproic acid has been researched along with Catatonia in 16 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Catatonia: A neuropsychiatric disorder characterized by one or more of the following essential features: immobility, mutism, negativism (active or passive refusal to follow commands), mannerisms, stereotypies, posturing, grimacing, excitement, echolalia, echopraxia, muscular rigidity, and stupor; sometimes punctuated by sudden violent outbursts, panic, or hallucinations. This condition may be associated with psychiatric illnesses (e.g., SCHIZOPHRENIA; MOOD DISORDERS) or organic disorders (NEUROLEPTIC MALIGNANT SYNDROME; ENCEPHALITIS, etc.). (From DSM-IV, 4th ed, 1994; APA, Thesaurus of Psychological Index Terms, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with schizoaffective disorder developed signs of catatonia while on a regimen of valproic acid, sertraline, and risperidone." | 7.70 | Catatonia-like events after valproic acid with risperidone and sertraline. ( Lauterbach, EC, 1998) |
| " valproate) were studied in rats against perphenazine-induced catatonia." | 7.67 | GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats. ( Garg, SK; Kulkarni, SK; Mathur, VS; Shukla, VK, 1985) |
| "We encountered catatonia in a man with neurosyphilis after increasing aripiprazole and valproate (drugs reported to improve catatonia) and reducing doxycycline and temazepam dosages, consistent with identified dopamine D2, serotonin 5HT2, and 5HT1a (aripiprazole), GABA-B (valproate), glutamatergic NMDA (aripiprazole, valproate, doxycycline), and GABA-A (aripiprazole, temazepam) mechanisms of catatonia." | 3.75 | Catatonia and CPK elevation in neurosyphilis: role of plural pharmacodynamic mechanisms. ( Carter, WG; Lauterbach, EC; Norris, BK; Shillcutt, SD, 2009) |
| "A patient with schizoaffective disorder developed signs of catatonia while on a regimen of valproic acid, sertraline, and risperidone." | 3.70 | Catatonia-like events after valproic acid with risperidone and sertraline. ( Lauterbach, EC, 1998) |
| " valproate) were studied in rats against perphenazine-induced catatonia." | 3.67 | GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats. ( Garg, SK; Kulkarni, SK; Mathur, VS; Shukla, VK, 1985) |
| "Hyperammonemic encephalopathy secondary to the use of valproate is rare without evidence of hepatotoxicity, and it usually presents with confusion, agitation, irritability, cognitive disturbances, lethargy, coma, and death." | 1.48 | Valproate-induced Hyperammonemic Encephalopathy Presenting as Catatonia. ( Espínola-Nadurille, M; Oñate-Cadena, N; Pérez-Esparza, R; Ramírez-Bermúdez, J, 2018) |
| "Treatment with valproic acid for bipolar disorder resulted in complete resolution of symptoms." | 1.46 | A Case of Recurrent Hypersomnia With Autonomic Dysfunction. ( Friedman, D; Kothare, SV; Mahmoudi, M; Vendrame, M, 2017) |
| "We present two cases of catatonia occurring in context of SC use." | 1.43 | Catatonia secondary to synthetic cannabinoid use in two patients with no previous psychosis. ( Gordon, M; Khan, M; Moukaddam, N; Pace, L; Truong, A, 2016) |
| "It shows the importance of recognising catatonia as a symptom of delirious mania." | 1.36 | What works for delirious catatonic mania? ( Grunze, H; Vasudev, K, 2010) |
| "We describe a case of catatonia in a 51-year-old man in whom the catatonic symptoms could not be distinguished from symptoms of frontotemporal dementia (FTD) until they were resolved with electroconvulsive therapy (ECT)." | 1.35 | A case of catatonia resembling frontotemporal dementia and resolved with electroconvulsive therapy. ( Matsuoka, H; Suzuki, K; Takano, T, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| de Neeling, M | 1 |
| van Paesschen, W | 1 |
| Mahmoudi, M | 1 |
| Friedman, D | 1 |
| Vendrame, M | 1 |
| Kothare, SV | 1 |
| Pérez-Esparza, R | 1 |
| Oñate-Cadena, N | 1 |
| Ramírez-Bermúdez, J | 1 |
| Espínola-Nadurille, M | 1 |
| Ene-Stroescu, V | 1 |
| Nguyen, T | 1 |
| Waiblinger, BE | 1 |
| Gélisse, P | 1 |
| Crespel, A | 1 |
| Barnhorst, A | 1 |
| Xiong, GL | 1 |
| Khan, M | 1 |
| Pace, L | 1 |
| Truong, A | 1 |
| Gordon, M | 1 |
| Moukaddam, N | 1 |
| Val, AC | 1 |
| Souza, A | 1 |
| Nicolato, R | 1 |
| Teixeira, AL | 1 |
| Salgado, JV | 1 |
| Lauterbach, EC | 3 |
| Norris, BK | 1 |
| Carter, WG | 1 |
| Shillcutt, SD | 1 |
| Carroll, B | 1 |
| Yoho, SD | 1 |
| Bottoms, JM | 1 |
| Vasudev, K | 1 |
| Grunze, H | 1 |
| Bowers, R | 1 |
| Ajit, SS | 1 |
| Suzuki, K | 1 |
| Takano, T | 1 |
| Matsuoka, H | 1 |
| Shukla, VK | 1 |
| Garg, SK | 1 |
| Mathur, VS | 1 |
| Kulkarni, SK | 1 |
16 other studies available for valproic acid and Catatonia
| Article | Year |
|---|---|
Stupor in a catatonic patient due to an interaction between high-dose lorazepam and valproic acid: a case report.
Topics: Adult; Anti-Anxiety Agents; Antimanic Agents; Catatonia; Drug Interactions; Female; Humans; Lorazepa | 2021 |
A Case of Recurrent Hypersomnia With Autonomic Dysfunction.
Topics: Antimanic Agents; Autonomic Nervous System Diseases; Bipolar Disorder; Catatonia; Disorders of Exces | 2017 |
Valproate-induced Hyperammonemic Encephalopathy Presenting as Catatonia.
Topics: Adult; Anticonvulsants; Brain Diseases; Catatonia; Epilepsy; Female; Humans; Hyperammonemia; Valproi | 2018 |
Successful treatment of catatonia in a young man with schizophrenia and progressive diffuse cerebral atrophy.
Topics: Adolescent; Amantadine; Anticonvulsants; Antiparkinson Agents; Antipsychotic Agents; Atrophy; Catato | 2014 |
Mixed myoclonic-absence status epilepticus in juvenile myoclonic epilepsy.
Topics: Anticonvulsants; Bipolar Disorder; Catatonia; Clonazepam; Electroencephalography; Epilepsies, Myoclo | 2015 |
Pulmonary embolism in a psychiatric patient.
Topics: Adult; Aggression; Antipsychotic Agents; Autopsy; Benzodiazepines; Bipolar Disorder; Catatonia; Deat | 2014 |
Catatonia secondary to synthetic cannabinoid use in two patients with no previous psychosis.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cannabinoids; Catatonia; Drug Thera | 2016 |
[Catatonic syndrome associated with mixed bipolar disorder: a case report and therapeutic considerations].
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Catatonia; Clonazepam; Female; Humans; Middle A | 2008 |
Catatonia and CPK elevation in neurosyphilis: role of plural pharmacodynamic mechanisms.
Topics: Adult; Aripiprazole; Catatonia; Creatine Kinase; Dose-Response Relationship, Drug; Doxycycline; Huma | 2009 |
Periodic catatonia.
Topics: Anticonvulsants; Antipsychotic Agents; Catatonia; Comorbidity; Drug Resistance; Drug Therapy, Combin | 2011 |
What works for delirious catatonic mania?
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Catatonia; Combined Modality Therapy; Deli | 2010 |
Is there a role for valproic acid in the treatment of catatonia?
Topics: Anticonvulsants; Catatonia; Female; Humans; Middle Aged; Receptors, GABA; Valproic Acid | 2007 |
A case of catatonia resembling frontotemporal dementia and resolved with electroconvulsive therapy.
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Antimanic Agents; Atrophy; Atropine; Bipolar Disorder; Cata | 2009 |
Catatonia-like events after valproic acid with risperidone and sertraline.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Catatonia; Drug Interactions; D | 1998 |
Valproate for catatonia: need for caution in patients on SSRIs and antipsychotics.
Topics: Anticonvulsants; Antipsychotic Agents; Catatonia; Drug Interactions; Humans; Schizophrenia, Catatoni | 2002 |
GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats.
Topics: Animals; Bromocriptine; Catatonia; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Ac | 1985 |