valproic acid has been researched along with Cardiovascular Abnormalities in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Cardiovascular Abnormalities: Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproate exposed embryos have microcephaly and disrupted cardiovasculature with delayed vessel circulation, thrombus formation, and slow heart rate." | 1.38 | Valproate-induced teratogenesis in Japanese rice fish (Oryzias latipes) embryogenesis. ( Dasmahapatra, AK; Khan, IA; Wu, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, M | 1 |
| Khan, IA | 1 |
| Dasmahapatra, AK | 1 |
| Artama, M | 1 |
| Auvinen, A | 1 |
| Raudaskoski, T | 1 |
| Isojärvi, I | 1 |
| Isojärvi, J | 1 |
2 other studies available for valproic acid and Cardiovascular Abnormalities
| Article | Year |
|---|---|
Valproate-induced teratogenesis in Japanese rice fish (Oryzias latipes) embryogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Cardiovascular Abnormalities; Cell Cycle Proteins; Embryo, Non | 2012 |
Antiepileptic drug use of women with epilepsy and congenital malformations in offspring.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Cardiovascular Abnormalities; Cleft Palate; Coh | 2005 |