valproic acid has been researched along with Cardiac Failure in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the hazard for all-cause mortality and mortality due to heart failure (HF) between valproate (VPA) and levetiracetam (LEV)/lamotrigine (LTG) users in patients aged ≥ 65 with comorbidities of epilepsy and HF." | 8.12 | The Relationship Between Valproate and Lamotrigine/Levetiracetam Use and Prognosis in Patients With Epilepsy and Heart Failure: A Danish Register-Based Study. ( Gardella, E; Kragholm, K; Liang, D; Polcwiartek, C; Sessa, M, 2022) |
| "To compare the hazard for all-cause mortality and mortality due to heart failure (HF) between valproate (VPA) and levetiracetam (LEV)/lamotrigine (LTG) users in patients aged ≥ 65 with comorbidities of epilepsy and HF." | 4.12 | The Relationship Between Valproate and Lamotrigine/Levetiracetam Use and Prognosis in Patients With Epilepsy and Heart Failure: A Danish Register-Based Study. ( Gardella, E; Kragholm, K; Liang, D; Polcwiartek, C; Sessa, M, 2022) |
| " Replacement of phenytoin by valproic acid resulted in a 100-lb weight gain, exacerbation of sleep apnea, and right heart failure." | 3.73 | Lethal obesity associated with sodium valproate in a brain-injured patient. ( Althoff, RR; Black, DN; Daye, K; Pelletier, CA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, D | 1 |
| Gardella, E | 1 |
| Kragholm, K | 1 |
| Polcwiartek, C | 1 |
| Sessa, M | 1 |
| Chen, J | 1 |
| Wang, D | 1 |
| Fang, C | 1 |
| Zong, NC | 1 |
| Liem, DA | 1 |
| Cadeiras, M | 1 |
| Scruggs, SB | 1 |
| Yu, H | 1 |
| Kim, AK | 1 |
| Yang, P | 1 |
| Deng, M | 1 |
| Lu, H | 1 |
| Ping, P | 1 |
| Black, DN | 1 |
| Althoff, RR | 1 |
| Daye, K | 1 |
| Pelletier, CA | 1 |
4 other studies available for valproic acid and Cardiac Failure
| Article | Year |
|---|---|
The Relationship Between Valproate and Lamotrigine/Levetiracetam Use and Prognosis in Patients With Epilepsy and Heart Failure: A Danish Register-Based Study.
Topics: Aged; Anticonvulsants; Cohort Studies; Denmark; Epilepsy; Heart Failure; Humans; Lamotrigine; Leveti | 2022 |
Impaired cardiovascular function caused by different stressors elicits a common pathological and transcriptional response in zebrafish embryos.
Topics: Animals; Carbaryl; Cell Proliferation; Disease Models, Animal; Edema, Cardiac; Embryo, Nonmammalian; | 2013 |
Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human.
Topics: Acetylation; Animals; Chromatography, Liquid; Gene Expression Regulation; Heart Failure; Heart Trans | 2013 |
Lethal obesity associated with sodium valproate in a brain-injured patient.
Topics: Adult; Anticonvulsants; Brain Injuries; Epilepsy; Fatal Outcome; Heart Failure; Humans; Male; Obesit | 2005 |