valproic acid has been researched along with Carcinoma, Embryonal in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Carcinoma, Embryonal: A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of breast cancer cells with a demethylating agent and histone deacetylase inhibitors reduced methylation of the CR-1 promoter and reactivated CR-1 mRNA and protein expression in these cells, promoting migration and invasion of breast cancer cells." | 1.39 | Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells. ( Baraty, C; Bianco, C; Castro, NP; Gonzales, M; Held, N; Karasawa, H; Rangel, MC; Rollman, K; Salomon, DS; Strizzi, L, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bianco, C | 1 |
| Castro, NP | 1 |
| Baraty, C | 1 |
| Rollman, K | 1 |
| Held, N | 1 |
| Rangel, MC | 1 |
| Karasawa, H | 1 |
| Gonzales, M | 1 |
| Strizzi, L | 1 |
| Salomon, DS | 1 |
| Faiella, A | 1 |
| Wernig, M | 1 |
| Consalez, GG | 1 |
| Hostick, U | 1 |
| Hofmann, C | 1 |
| Hustert, E | 1 |
| Boncinelli, E | 1 |
| Balling, R | 1 |
| Nadeau, JH | 1 |
2 other studies available for valproic acid and Carcinoma, Embryonal
| Article | Year |
|---|---|
Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells.
Topics: Azacitidine; Binding Sites; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Embryonal; Cell | 2013 |
A mouse model for valproate teratogenicity: parental effects, homeotic transformations, and altered HOX expression.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Carcinoma, Embryonal | 2000 |