valproic acid has been researched along with Cancer of Gastrointestinal Tract in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gastrointestinal and pulmonary carcinoid cells were treated with either VPA or SBHA and lithium chloride for up to 48 hours." | 5.35 | Combination therapy with histone deacetylase inhibitors and lithium chloride: a novel treatment for carcinoid tumors. ( Adler, JT; Chen, H; Hottinger, DG; Kunnimalaiyaan, M, 2009) |
| "Gastrointestinal and pulmonary carcinoid cells were treated with either VPA or SBHA and lithium chloride for up to 48 hours." | 1.35 | Combination therapy with histone deacetylase inhibitors and lithium chloride: a novel treatment for carcinoid tumors. ( Adler, JT; Chen, H; Hottinger, DG; Kunnimalaiyaan, M, 2009) |
| "Carcinoid tumors are neuroendocrine malignancies that frequently metastasize and secrete hormones that cause debilitating symptoms in patients." | 1.34 | Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells. ( Chen, H; Greenblatt, DY; Haymart, M; Jaskula-Sztul, R; Kunnimalaiyaan, M; Ning, L; Vaccaro, AM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adler, JT | 1 |
| Hottinger, DG | 1 |
| Kunnimalaiyaan, M | 2 |
| Chen, H | 2 |
| Greenblatt, DY | 1 |
| Vaccaro, AM | 1 |
| Jaskula-Sztul, R | 1 |
| Ning, L | 1 |
| Haymart, M | 1 |
2 other studies available for valproic acid and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Combination therapy with histone deacetylase inhibitors and lithium chloride: a novel treatment for carcinoid tumors.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Carcinoid | 2009 |
Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells.
Topics: Animals; Antineoplastic Agents; Carcinoid Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; C | 2007 |