Page last updated: 2024-10-26

valproic acid and Burns

valproic acid has been researched along with Burns in 5 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to examine whether administration of valproic acid (VPA) improves blood circulation and survival after lethal burn shock."7.78The effect of valproic acid in alleviating early death in burn shock. ( Hou, JY; Hu, S; Sheng, ZY; Wang, HB; Yang, M, 2012)
"The aim of this study was to examine whether administration of valproic acid (VPA) improves blood circulation and survival after lethal burn shock."3.78The effect of valproic acid in alleviating early death in burn shock. ( Hou, JY; Hu, S; Sheng, ZY; Wang, HB; Yang, M, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tang, FB1
Dai, YL1
Zhou, GY1
Zhang, WH1
Wang, HB2
Li, YG1
Luo, HM2
Hu, S5
Luo, H2
Bian, H1
Zheng, S1
Xiong, B1
Huang, Z1
Liu, Z1
Sun, C1
Ma, L3
Li, H1
Yu, W2
Du, M2
Chen, H1
Lai, W1
Du, MH1
Lin, ZL1
Zhang, L1
Wang, H3
Lv, Y1
Lu, JY1
Pi, YL1
Sheng, ZY2
Bai, H1
Lin, Z1
Lyu, Y1
Sheng, Z1
Hou, JY1
Yang, M1

Other Studies

5 other studies available for valproic acid and Burns

ArticleYear
Valproic Acid Treatment Inhibits Vasopermeability and Improves Survival in Rats With Lethal Scald Injury.
    Journal of burn care & research : official publication of the American Burn Association, 2018, 02-20, Volume: 39, Issue:2

    Topics: Animals; Burns; Capillary Permeability; Cell Culture Techniques; Disease Models, Animal; Endothelial

2018
[Protective effects of valproic acid on gut barrier function after major burn injury and its mechanism].
    Zhonghua wei zhong bing ji jiu yi xue, 2017, Volume: 29, Issue:3

    Topics: Animals; Burns; Intestines; Male; Rats; Rats, Sprague-Dawley; Valproic Acid; Vascular Endothelial Gr

2017
Valproic acid treatment inhibits hypoxia-inducible factor 1α accumulation and protects against burn-induced gut barrier dysfunction in a rodent model.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Acetylation; Animals; Burns; Caco-2 Cells; Disease Models, Animal; Gastroenteritis; Histones; Humans

2013
[The protective effect of valproic acid on myocardium in rats with lethal scald injury and its mechanism].
    Zhonghua wei zhong bing ji jiu yi xue, 2014, Volume: 26, Issue:8

    Topics: Acetylation; Animals; Burns; Cardiotonic Agents; Caspase 3; Creatine Kinase, MB Form; Disease Models

2014
The effect of valproic acid in alleviating early death in burn shock.
    Burns : journal of the International Society for Burn Injuries, 2012, Volume: 38, Issue:1

    Topics: Animals; Biomarkers; Burns; Dogs; Enzyme Inhibitors; Hemodynamics; Intestinal Mucosa; Models, Animal

2012