valproic acid and Brain Diseases

valproic acid has been researched along with Brain Diseases in 126 studies

Research

Studies (126)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (12.70)	18.7374
1990's	23 (18.25)	18.2507
2000's	29 (23.02)	29.6817
2010's	38 (30.16)	24.3611
2020's	20 (15.87)	2.80

Authors

Authors	Studies
Chen, L; Huang, H; Xu, Z	1
Anthonipillai, P; Kimber, J; Sharp, G; Ziauddin, V	1
Bryant, C; Chetwood, JD; Koorey, D	1
Bloemkolk, D; Gerritse, FL; Rundervoort, RS; van Haaren, PCF	1
Fang, Y; Fang, Z; Hui, L; Yu-E, Y; Zheng-Li, D; Zhi-Qin, L	1
Liu, X; Peng, X	1
Gupta, S; Sharma, DS; Sharma, P	1
Beuchat, I; Loser, V; Novy, J; Rossetti, AO	1
Arias-Vivas, E; Duat-Rodríguez, A; García-Peñas, JJ; González-Alguacil, E; Gutiérrez-Delicado, E; Heppe-Montero, M; Justel-Rodríguez, M; Ordoño-Saiz, MV; Púa-Torrejón, RC; Ruiz-Falcó-Rojas, ML; Soto-Insuga, V	1
Abeysundera, H; Jeyaranjan, H; Ranjith, S	1
Baumgartner, J; Fellinger, M; Frey, R; Friedrich, F; Graf, I; Hinterbuchinger, B; Hoeflich, A; Mossaheb, N	1
Jiang, Z; Li, B; Li, J; Li, Y; Wang, L; Zhang, T	1
Shah, S; Vieux, U; Wang, R	1
Hodes, JF; Hu, XY; Lu, PL; Zheng, X	1
Croom, JE; Fields, RK; Ilieva, HS; Newman, JW	1
Fu, L; Li, SQ; Pei, W; Yu, Y	1
Edquist, C; O'Rourke, N; Pagali, S	1
Jing, W; Li, J; Tian, X; Wang, X; Wu, J	1
Kazmierski, D; O'Leary, K; Ochieng, P; Sharma, N	1
Chen, M; Lv, D; Yang, Y; Zhao, K	1
Pellegrino, F; Tardivo, I	1
Cherian, KA; Legatt, AD	1
Chatterjee, SS; Das, R; Das, S; Mitra, S	1
Abu Sitta, E; Gaddam, M; Kanzy, A; Velagapudi, RK	1
Ceberio-Hualde, L; Cebrian-Novella, D; Diaz Alvarez-Mediavilla, J; Gomez-Del Olmo, V; Nava-Mateos, JJ; Roiz-Rey, P	1
Avila-Cabreja, JA; Fernandez-Massip, H; Fornaris-Cedeno, Y; Sosa-Gonzalez, I	1
Espínola-Nadurille, M; Oñate-Cadena, N; Pérez-Esparza, R; Ramírez-Bermúdez, J	1
Camilleri, L	1
Geer, K; Izadi Firouzabadi, L; Mead, P	1
Arcos Sánchez, C; Montes Castro, N; Vicente Gordo, D; Viloria Alebesque, A	1
Lucie, O; Nazir, F; Spilg, E	1
Jo, YH; Kang, C; Kim, J; Kim, K; Kim, MA; Lee, JH; Lee, MJ; Lee, SH; Park, CJ; Rhee, JE	1
Sendrowski, K; Sobaniec, P; Sobaniec, W; Sobaniec-Lotowska, ME	1
Belze, O; Fusciardi, J; Pujol, A; Remérand, F	1
Dubynin, VA; Malyshev, AV; Myasoedov, NF; Razumkina, EV	1
Amanat, S; Hassan, Y; Shahbaz, N	1
Dong, L; Ji, M; Jia, M; Qiu, L; Wu, J; Yang, J; Zhang, G; Zhang, M	1
Budhdeo, S; Marquette, M; Rajagopal, V; Singh, D	1
Larsen, EP; Ostergaard, JR	1
Boletis, JN; Darema, M; Efthimiou, A; Marinaki, S; Melexopoulou, C; Skalioti, C; Zavos, G	1
Balkovec, V; Rener-Primec, Z	1
Christensen, J; Harbo, T; Prakash, S	2
Ali, EH; Elgoly, AH; Hegazy, HG	1
Arroyo Pérez, R; Fernández-Candil, JL; León Jorba, A; Pacreu Terradas, S; Villalba Martínez, G; Vivanco-Hidalgo, RM	1
Chen, X; Su, Z; Wu, Z; Ye, S; Zhu, D; Zhuge, G	1
Al-sharefi, A; Bilous, R	1
Hwang, JE; Jo, YH; Kim, K; Kim, MA; Lee, JH; Lee, MJ	1
Dawson, LP; Hollander, YS; Lee, SJ	1
Celebisoy, N; Ciftci, S; Deveci, E; Guler, A; Yuceyar, N	1
Corsini, GP; Gandolfo, F; Monacelli, F; Odetti, P; Parodi, MN; Serafini, G	1
Birur, B; Fargason, RE; Landry, KB; Patel, N	1
Hronová, K; Klement, P; Pokorná, P; Šíma, M; Slanař, O; Tibboel, D; van den Anker, JN	1
Chen, CY; Tsai, MF	1
LaRoche, SM; Shivdat-Nanhoe, R	1
Gynther, M; Isotalo, A; Laine, K; Leppänen, J; Malmioja, K; Peura, L; Rautio, J	1
Chatterjee, R; Das, S; Guha, G; Hasmi, MA; Joardar, S	1
Chu, K; Jung, KH; Kim, DW; Lee, SK; Lee, ST; Moon, HJ; Noh, Y	1
Lainez, E; Macaya-Ruiz, A; Raspall-Chaure, M; Roig-Quilis, M; Salas-Puig, J; Toledo, M	1
Chiarelli, F; Morgese, G; Trotta, D; Verrotti, A	1
Yoshimura, K	1
Sobaniec-Lotowska, ME	2
Kimura, M; Suzuki, H	2
Asztely, F; Eriksson, B; Lokrantz, CM; Rosén, I	1
Fallgatter, AJ; Leonhard, C; Lesch, KP; Mössner, R; Reif, A	1
Irwin, SA; Kimmel, RJ; Meyer, JM	1
Cheung, E; Fung, CW; Wong, V	1
Rehman, A; Zafar, S	1
Thygesen, KS; Wolf, P	1
Augspach-Hofmann, R; Bendl, C; Buesing, D; Fitzek, S; Gerstner, T; Goetze, G; Haensch, CA; Klostermann, W; Koenig, SA; Lippert, G; Longin, E; Macke, A; Mayer, G; Reuland, M; Scheid, B; Wenzel, D	1
Andrade, DM; Del Campo, JM; Wennberg, R; Zumsteg, D	1
Morrison, PF; Sankar, R; Shields, WD	1
Cai, FC; Zhang, XP; Zhu, HX	1
Blum, W; Byrd, JC; Chan, KK; Devine, H; Devine, SM; Grever, MR; Hackanson, B; Heerema, NA; Huynh, L; Kefauver, C; Klisovic, RB; Liu, S; Liu, Z; Lozanski, G; Marcucci, G; Murgo, A; Plass, C; Vukosavljevic, T	1
Jedrzejczak, J; Kuncíková, M; Magureanu, S	1
Modjtahedi, B; Xiong, GL	1
Bauer, J	1
Alvarez, F; Bruetman, JE; Finn, BC; Trimarchi, H; Young, P	1
Allen, RJ; Coulter, DL	1
Arnetoli, G; Boncinelli, L; Campostrini, R; Paganini, M; Zaccara, G; Zappoli, R	1
Beckner, RR; Marini, AM; Passarelli, C; Wagle, W; Zaret, BS	1
Axelgaard, G	1
Apicella, P; De Giorgio, LA; Innocenti, F; Pettiná, G; Seghieri, G; Zolfanelli, F	1
Aicardi, J; Alfonso, I; Archila, R; Cañizales, E; Duchowny, M; Papazian, O	1
Averbuch-Heller, L; Ben-Hur, T; Reches, A	1
Aihara, N; Ishikawa, T; Kamiya, K; Kanayama, M; Katano, H; Nagai, H; Yamashita, N	1
Khan, EM; Puri, AS; Saraswat, VA; Sharma, BC	1
Bourgeois, BF; Chez, MG; Knowles, WD; Pippenger, CE	1
Bernard, G; Mattei, A; Paliard, P; Plauchu, G	1
Hennessy, MJ; Wiles, CM	1
Fukuzumi, A; Kuwahara, M; Nakai, H; Nishino, M; Shima, M; Yoshioka, A	1
Sobaniec, W; Sobaniec-Lotowska, ME	1
Garaizar, C; Lambarri, I; Martín, MA; Prats, JM; Sousa, T	1
Aumaitre, O; Biousse, V; Bousser, MG; Fardeau, C; Godeau, P; Huong, DL; Lehoang, P; N'Guyen, N; Papo, T; Piette, JC	1
Belmonte, A; Canapicchi, R; Casalini, C; Guerrini, R; Perucca, E	1
Amano, T; Ichikawa, H; Kawabata, K; Kushiro, M; Makino, H; Nagake, Y; Wada, J	1
Bräunig, P; Göbel, R; Görtzen, A	1
Gaily, E; Granström, ML; Liukkonen, E	1
Adèr, HJ; Beenen, LF; Heimans, JJ; Kasteleijn-Nolst Trenité, DG; Lindeboom, J; Snoek, FJ; Touw, DJ; van Alphen, HA	1
Hamer, HM; Knake, S; Rosenow, F; Schomburg, U	1
Hirata, K; Katayama, S; Miyamoto, M; Miyamoto, T	1
Calvani, M; Guaitolini, C; Paolone, G; Parisi, G; Parisi, P	1
Cuber, JC; Dumont, O; Dumortier, J; Guegen, L; Paliard, P; Plauchu, G; Scoazec, JY	1
Temkin, NR	1
Chen, WT; Liao, KK; Yen, DJ; Yu, HY	1
Cawthon, DF; Caylor, LM; Kraemer, DL; Morgan, JD; Ojemann, LM; Vossler, DG; Wilensky, AJ	1
Augustynowicz, A; Sobaniec, W; Sobaniec-Lotowska, M	1
Cartlidge, NE; Chadwick, DW; Cumming, WJ; Livingstone, I	1
Fahn, S	1
Binnie, CD; de Beer-Pawlikowski, NK; Goedhart, DM; Gutter, T; Meijer, JW; Meinardi, H; Rowan, AJ; van der Geest, P	1
Fukusako, T; Morimatsu, M; Nogaki, H; Yamamoto, K	1
Kobayashi, Y; Kuhara, T; Matsumoto, I; Murakami, K; Nishida, N; Sugimoto, T	1
Khoo, SH; Leyland, MJ	1
Buffa, C; Gentile, S; Ravetti, C; Sacerdote, I	1
Smith, DB	1
Chowdhury, V; Gulati, P; Puri, V	1
Bentsen, KD; Gram, L	1
Gale, K	1
Cornford, EM; Oldendorf, WH	1
Wallace, SJ	1
Goto, S; Ichikawa, M; Matsuyama, K; Miyazaki, C	1
Gastaut, JL; Mege, JL	1
Manni, R; Tartara, A	1
Fukuyama, Y; Izumi, T; Osawa, M; Utsumi, H	1

Reviews

13 review(s) available for valproic acid and Brain Diseases

Article	Year
A potential cause of adolescent onset Dyke-Davidoff-Masson syndrome: A case report. Medicine, 2019, Volume: 98, Issue:51 Topics: Brain Diseases; Carbamazepine; China; Chronic Disease; Female; Humans; Intellectual Disability; Magnetic Resonance Imaging; Prognosis; Recurrence; Risk Assessment; Seizures; Severity of Illness Index; Syndrome; Tomography, X-Ray Computed; Valproic Acid; Young Adult	2019
Valproic acid-induced encephalopathy: A review of clinical features, risk factors, diagnosis, and treatment. Epilepsy & behavior : E&B, 2021, Volume: 120 Topics: Anticonvulsants; Brain Diseases; Humans; Hyperammonemia; Risk Factors; Valproic Acid	2021
Lesson of the month 1: Sodium valproate-induced encephalopathy. Clinical medicine (London, England), 2018, Volume: 18, Issue:5 Topics: Aged; Ammonia; Anticonvulsants; Brain Diseases; Carnitine; Consciousness Disorders; Epilepsy; Humans; Hyperammonemia; Male; Polypharmacy; Valproic Acid	2018
Valproic acid-induced hyperammonemic encephalopathy in a full-term neonate: a brief review and case report. European journal of clinical pharmacology, 2017, Volume: 73, Issue:5 Topics: Anticonvulsants; Brain Diseases; Humans; Hyperammonemia; Infant, Newborn; Seizures; Valproic Acid	2017
Valproate-induced hyperammonemic encephalopathy. Metabolic brain disease, 2002, Volume: 17, Issue:4 Topics: Anticonvulsants; Brain Diseases; Humans; Hyperammonemia; Valproic Acid	2002
[Organic manic disorder]. Ryoikibetsu shokogun shirizu, 2003, Issue:40 Topics: Bipolar Disorder; Brain Diseases; Carbamazepine; Clonazepam; Diagnostic and Statistical Manual of Mental Disorders; Humans; International Classification of Diseases; Lithium Carbonate; Valproic Acid	2003
[Organic bipolar disorder]. Ryoikibetsu shokogun shirizu, 2003, Issue:40 Topics: Bipolar Disorder; Brain Diseases; Carbamazepine; Humans; International Classification of Diseases; Lithium Carbonate; Psychotropic Drugs; Valproic Acid	2003
Susac syndrome. Medicine, 1998, Volume: 77, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Audiometry, Pure-Tone; Brain Diseases; Cyclophosphamide; Diagnosis, Differential; Drug Therapy, Combination; Female; Fluorescein Angiography; GABA Agents; Hearing Loss, Sensorineural; Humans; Magnetic Resonance Imaging; Methylprednisolone; Prednisone; Retinal Artery Occlusion; Syndrome; Valproic Acid	1998
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials. Epilepsia, 2001, Volume: 42, Issue:4 Topics: Anticonvulsants; Brain Diseases; Brain Injuries; Carbamazepine; Controlled Clinical Trials as Topic; Diazepam; Epilepsy; Humans; Lorazepam; Models, Statistical; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk; Seizures; Treatment Outcome; Valproic Acid	2001
Cognitive effects of antiepileptic drugs. Advances in neurology, 1991, Volume: 55 Topics: Anticonvulsants; Brain Diseases; Carbamazepine; Cognition; Drug Tolerance; Humans; Phenobarbital; Phenytoin; Valproic Acid	1991
Valproate: an updated review. Acta neurologica Scandinavica, 1985, Volume: 72, Issue:2 Topics: Abnormalities, Drug-Induced; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Dyskinesia, Drug-Induced; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Huntington Disease; Infant; Pancreatitis; Parkinson Disease; Seizures, Febrile; Spasms, Infantile; Status Epilepticus; Tremor; Trigeminal Neuralgia; Valproic Acid	1985
Epilepsy and the blood-brain barrier. Advances in neurology, 1986, Volume: 44 Topics: Animals; Animals, Newborn; Anticonvulsants; Biological Transport; Biomechanical Phenomena; Blood Proteins; Blood-Brain Barrier; Brain; Brain Diseases; Capillaries; Capillary Permeability; Cerebrovascular Circulation; Epilepsy; Forecasting; Lipids; Mammals; Peptides; Seizures; Valproic Acid	1986
Use of ethosuximide and valproate in the treatment of epilepsy. Neurologic clinics, 1986, Volume: 4, Issue:3 Topics: Abnormalities, Drug-Induced; Brain Diseases; Drug Interactions; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Status Epilepticus; Succinimides; Trimethadione; Valproic Acid	1986

Trials

4 trial(s) available for valproic acid and Brain Diseases

Article	Year
Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Sep-01, Volume: 25, Issue:25 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Diseases; Decitabine; Fatigue; Humans; Infections; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Neutropenia; Remission Induction; Treatment Failure; Valproic Acid	2007
An observational study of first-line valproate monotherapy in focal epilepsy. European journal of neurology, 2008, Volume: 15, Issue:1 Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Brain Diseases; Child; Delayed-Action Preparations; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Female; Gastrointestinal Diseases; Humans; International Cooperation; Male; Middle Aged; Prospective Studies; Skin Diseases; Treatment Outcome; Valproic Acid; Weight Gain	2008
Treatment of infantile spasms: results of a population-based study with vigabatrin as the first drug for spasms. Epilepsia, 1999, Volume: 40, Issue:7 Topics: 4-Aminobutyrate Transaminase; Adrenocorticotropic Hormone; Anticonvulsants; Brain Diseases; Child; Clinical Protocols; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Finland; gamma-Aminobutyric Acid; Humans; Incidence; Magnetic Resonance Imaging; Spasms, Infantile; Tomography, X-Ray Computed; Treatment Outcome; Valproic Acid; Videotape Recording; Vigabatrin	1999
Comparative double blind clinical trial of phenytoin and sodium valproate as anticonvulsant prophylaxis after craniotomy: efficacy, tolerability, and cognitive effects. Journal of neurology, neurosurgery, and psychiatry, 1999, Volume: 67, Issue:4 Topics: Adult; Aged; Brain Diseases; Cognition; Craniotomy; Double-Blind Method; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin; Quality of Life; Time Factors; Valproic Acid	1999

Other Studies

109 other study(ies) available for valproic acid and Brain Diseases

Article	Year
Non-hyperammonaemia valproate-induced encephalopathy: A case report. Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:3 Topics: Anticonvulsants; Brain Diseases; Epilepsy; Female; Humans; Hyperammonemia; Middle Aged; Valproic Acid	2022
Valproate-Associated Hyperammonaemic Encephalopathy. Acute medicine, 2022, Volume: 21, Issue:1 Topics: Anticonvulsants; Brain Diseases; Humans; Hyperammonemia; Male; Middle Aged; Neurotoxicity Syndromes; Valproic Acid	2022
Hyperammonaemic encephalopathy. Internal medicine journal, 2022, Volume: 52, Issue:4 Topics: Brain Diseases; Humans; Neurotoxicity Syndromes; Valproic Acid	2022
[A severe, reversible encephalopathy after prolonged use of valproic acid]. Tijdschrift voor psychiatrie, 2023, Volume: 65, Issue:1 Topics: Aged; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Brain Diseases; Epilepsy; Female; Humans; Hyperammonemia; Valproic Acid	2023
Valproate-induced hyperammonemic encephalopathy treated by L-ornithine-L-aspartate: a case report. Clinical medicine (London, England), 2023, Volume: 23, Issue:3 Topics: Ammonia; Anticonvulsants; Brain Diseases; Humans; Male; Middle Aged; Valproic Acid	2023
Valproate-related hyperammonemic encephalopathy with generalized suppression EEG: a case report. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023, Volume: 44, Issue:10 Topics: Adult; Anticonvulsants; Brain Diseases; Electroencephalography; Epilepsy; Female; Humans; Hyperammonemia; Neurotoxicity Syndromes; Phenytoin; Valproic Acid	2023
Valproate overdose leading to hyperammonaemic encephalopathy. BMJ case reports, 2023, Jul-09, Volume: 16, Issue:7 Topics: Anticonvulsants; Brain Diseases; Humans; Hyperammonemia; Male; Neurotoxicity Syndromes; Valproic Acid	2023
Acute Valproate-Induced Encephalopathy in Status Epilepticus: A Registry-Based Assessment. CNS drugs, 2023, Volume: 37, Issue:8 Topics: Adult; Anticonvulsants; Brain Diseases; Humans; Hyperammonemia; Status Epilepticus; Valproic Acid	2023
Cerebral and cerebellar pseudoatrophy associated with valproic acid. Report of three pediatric cases. Revista de neurologia, 2023, 10-16, Volume: 77, Issue:8 Topics: Anticonvulsants; Brain; Brain Diseases; Cerebellum; Child; Child, Preschool; Epilepsy; Humans; Neurotoxicity Syndromes; Valproic Acid	2023
Unusual case of sodium valproate-induced hyperammonaemia encephalopathy. BMJ case reports, 2023, Nov-30, Volume: 16, Issue:11 Topics: Bipolar Disorder; Brain Diseases; Humans; Hyperammonemia; Male; Middle Aged; Neoplasm Recurrence, Local; Valproic Acid	2023
Fulminant Onset of Valproate-Associated Hyperammonemic Encephalopathy. The American journal of psychiatry, 2019, 11-01, Volume: 176, Issue:11 Topics: Adult; Anticonvulsants; Brain Diseases; Humans; Hyperammonemia; Male; Valproic Acid	2019
Valproate-induced hyperammonemic encephalopathy: a case report. Journal of medical case reports, 2020, Jan-25, Volume: 14, Issue:1 Topics: Antimanic Agents; Brain Diseases; Confusion; Female; Gait Ataxia; Humans; Hyperammonemia; Middle Aged; Valproic Acid	2020
Reversible Splenial Lesion Syndrome with Some Novel Causes and Clinical Manifestations. Internal medicine (Tokyo, Japan), 2020, Oct-15, Volume: 59, Issue:20 Topics: Adult; Anticonvulsants; Brain Diseases; Carbamazepine; Causality; Corpus Callosum; Female; Headache; Humans; Levetiracetam; Male; Middle Aged; Paraspinal Muscles; Prognosis; Retrospective Studies; Seizures; Valproic Acid; Vertigo; Young Adult	2020
Valproic acid and zonisamide induced hyperammonemic encephalopathy. Clinical neurology and neurosurgery, 2020, Volume: 196 Topics: Adult; Anticonvulsants; Brain; Brain Diseases; Epilepsy; Humans; Hyperammonemia; Magnetic Resonance Imaging; Male; Valproic Acid; Zonisamide	2020
Brain transcriptomics of nonhuman primates: A review. Neuroscience letters, 2021, 05-14, Volume: 753 Topics: Aging; Animals; Brain; Brain Diseases; Disease Models, Animal; Ethanol; Humans; Methamphetamine; Neurosciences; Primates; RNA-Seq; Sevoflurane; Transcriptome; Valproic Acid	2021
Managing valproic acid toxicity-related hyperammonaemia: an unpredicted course. BMJ case reports, 2021, Apr-19, Volume: 14, Issue:4 Topics: Adult; Brain Diseases; Carnitine; Drug Overdose; Female; Humans; Hyperammonemia; Valproic Acid; Young Adult	2021
Valproate-induced fatal acute hyperammonaemia-related encephalopathy in late-onset ornithine transcarbamylase deficiency. BMJ case reports, 2021, May-25, Volume: 14, Issue:5 Topics: Adult; Brain Diseases; Humans; Hyperammonemia; Male; Ornithine Carbamoyltransferase Deficiency Disease; Seizures; Valproic Acid	2021
Valproic-induced Hyperammonemic Encephalopathy Aggravated by Combined Use of Topiramate - A Case Report. Psychiatria Danubina, 2021,Summer, Volume: 33, Issue:2 Topics: Anticonvulsants; Brain Diseases; Humans; Topiramate; Valproic Acid	2021
SLC13A5-related epileptic encephalopathy successfully treated with valproate and acetazolamide. Seizure, 2021, Volume: 91 Topics: Acetazolamide; Brain Diseases; Epilepsy, Generalized; Humans; Symporters; Valproic Acid	2021
Burst Suppression Pattern on Electroencephalogram Secondary to Valproic Acid-Induced Hyperammonemic Encephalopathy. Pediatric neurology, 2017, Volume: 73 Topics: Adolescent; Anticonvulsants; Autistic Disorder; Brain Diseases; Electroencephalography; Epilepsy; Female; Humans; Hyperammonemia; Valproic Acid	2017
The damaged cortices and the uncontrolled Id: A case of post-measles hyper-sexuality. Asian journal of psychiatry, 2017, Volume: 30 Topics: Antipsychotic Agents; Brain; Brain Diseases; Child; Diagnosis, Differential; GABA Agents; Humans; Id; Male; Measles; Positron-Emission Tomography; Risperidone; Sexual Behavior; Valproic Acid	2017
Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning? BMJ case reports, 2017, Oct-15, Volume: 2017 Topics: Acid-Base Equilibrium; Acidosis; Anticonvulsants; Brain Diseases; Calcium Oxalate; Cognitive Dysfunction; Diagnosis, Differential; Epilepsy; Ethylene Glycol; Humans; Lactic Acid; Male; Medication Adherence; Middle Aged; Osmolar Concentration; Urolithiasis; Valproic Acid	2017
[Treatment of encephalopathy by means of valproic acid with carglumic acid. Reply]. Revista de neurologia, 2018, 02-16, Volume: 66, Issue:4 Topics: Anticonvulsants; Brain Diseases; Glutamates; Humans; Valproic Acid	2018
[Treatment of encephalopathy by means of valproic acid with carglumic acid]. Revista de neurologia, 2018, 02-16, Volume: 66, Issue:4 Topics: Anticonvulsants; Brain Diseases; Glutamates; Humans; Valproic Acid	2018
Valproate-induced Hyperammonemic Encephalopathy Presenting as Catatonia. The neurologist, 2018, Volume: 23, Issue:2 Topics: Adult; Anticonvulsants; Brain Diseases; Catatonia; Epilepsy; Female; Humans; Hyperammonemia; Valproic Acid; Young Adult	2018
Severe hyperammonaemic encephalopathy resulting from the overlap between hepatic and valproate encephalopathy. Postgraduate medical journal, 2018, Volume: 94, Issue:1117 Topics: Alcoholism; Brain Diseases; Epilepsy; Humans; Hyperammonemia; Hypertension, Portal; Male; Middle Aged; Neurotoxicity Syndromes; Treatment Outcome; Valproic Acid; Withholding Treatment	2018
Non-convulsive status epilepticus secondary to valproate-induced hyperammonaemic encephalopathy. Neurologia, 2020, Volume: 35, Issue:8 Topics: Anticonvulsants; Brain Diseases; Humans; Neurotoxicity Syndromes; Status Epilepticus; Valproic Acid	2020
A case of valproate-induced hyperammonaemic encephalopathy. Scottish medical journal, 2013, Volume: 58, Issue:1 Topics: Aged; Anticonvulsants; Brain Diseases; Female; Humans; Hyperammonemia; Valproic Acid	2013
Effect of valproic acid on survival and neurologic outcomes in an asphyxial cardiac arrest model of rats. Resuscitation, 2013, Volume: 84, Issue:10 Topics: Animals; Asphyxia; Brain Diseases; Disease Models, Animal; Enzyme Inhibitors; Heart Arrest; Male; Rats; Rats, Sprague-Dawley; Survival Rate; Valproic Acid	2013
Ultrastructural study of hippocampal cortex neurons in an experimental model of valproate encephalopathy. Folia histochemica et cytobiologica, 2013, Volume: 51, Issue:1 Topics: Animals; Brain Diseases; Cerebral Cortex; Cytoplasm; Disease Models, Animal; Hippocampus; Male; Neurons; Pyramidal Cells; Rats; Rats, Wistar; Valproic Acid	2013
Hyperammonaemic encephalopathy and a flat electroencephalogram caused by valproic acid. Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:8 Topics: Adult; Anesthesia, General; Anticonvulsants; Brain Diseases; Craniocerebral Trauma; Electroencephalography; Epilepsy, Tonic-Clonic; Glasgow Coma Scale; Humans; Hyperammonemia; Hypnotics and Sedatives; Male; Midazolam; Valproic Acid	2013
Semax corrects brain dysfunction caused by prenatal introduction of valproic acid. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2013, Volume: 450 Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Anticonvulsants; Brain Diseases; Female; Male; Neuroprotective Agents; Peptide Fragments; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Valproic Acid	2013
Valproic acid induced hyperammonaemic encephalopathy. JPMA. The Journal of the Pakistan Medical Association, 2013, Volume: 63, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Brain Diseases; Child; Child, Preschool; Cohort Studies; Epilepsy; Female; Humans; Hyperammonemia; Male; Pakistan; Valproic Acid; Young Adult	2013
Class I histone deacetylase inhibitor valproic acid reverses cognitive deficits in a mouse model of septic encephalopathy. Neurochemical research, 2013, Volume: 38, Issue:11 Topics: Animals; Brain Diseases; Brain-Derived Neurotrophic Factor; Carbazoles; Cecum; Cognition Disorders; Disease Models, Animal; Histone Deacetylase Inhibitors; Indole Alkaloids; Ligation; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Punctures; Receptor, trkB; Sepsis; Signal Transduction; Valproic Acid	2013
Normoammonemic encephalopathy: solely valproate induced or multiple mechanisms? BMJ case reports, 2014, Mar-10, Volume: 2014 Topics: Aged; Aggression; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Brain Diseases; Confusion; Delusions; Female; GABA Agents; Hallucinations; Humans; Migraine with Aura; Valproic Acid	2014
Valproate-induced hyperammonemia in juvenile ceroid lipofuscinosis (Batten disease). Seizure, 2014, Volume: 23, Issue:6 Topics: Adolescent; Anticonvulsants; Brain Diseases; Carnitine; Drug Therapy, Combination; Female; Humans; Hyperammonemia; Male; Neuronal Ceroid-Lipofuscinoses; Valproic Acid; Vitamin B Complex; Young Adult	2014
Valproate-induced hyperammonemic encephalopathy in a renal transplanted patient. Renal failure, 2014, Volume: 36, Issue:6 Topics: Adolescent; Anticonvulsants; Brain Diseases; Female; Humans; Hyperammonemia; Kidney Transplantation; Postoperative Complications; Valproic Acid	2014
Valproate-related erythrodermia with reversible encephalopathy: a rare but serious adverse reaction, case report. Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2014, Volume: 23, Issue:2 Topics: Anticonvulsants; Brain Diseases; Child, Preschool; Dermatitis, Exfoliative; Drug Eruptions; Humans; Male; Severity of Illness Index; Valproic Acid	2014
[Valproate can induce reversible encephalopathy]. Ugeskrift for laeger, 2014, Nov-03, Volume: 176, Issue:45 Topics: Aged; Anticonvulsants; Brain Diseases; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Neurotoxicity Syndromes; Valproic Acid	2014
Interplay between pro-inflammatory cytokines and brain oxidative stress biomarkers: evidence of parallels between butyl paraben intoxication and the valproic acid brain physiopathology in autism rat model. Cytokine, 2015, Volume: 71, Issue:2 Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autistic Disorder; Biomarkers; Brain; Brain Diseases; Chromatography, High Pressure Liquid; Female; Glutathione; Glutathione Disulfide; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mitochondria; Oxidative Stress; Parabens; Pregnancy; Rats, Wistar; Tumor Necrosis Factor-alpha; Tyrosine; Valproic Acid	2015
Ammonia encephalopathy and awake craniotomy for brain language mapping: cause of failed awake craniotomy. Revista espanola de anestesiologia y reanimacion, 2015, Volume: 62, Issue:5 Topics: Anesthesia, General; Anesthesia, Local; Anticonvulsants; Aphasia; Benzodiazepines; Brain Diseases; Brain Mapping; Brain Neoplasms; Carnitine; Clobazam; Conscious Sedation; Consciousness Disorders; Craniotomy; Dominance, Cerebral; Frontal Lobe; Glioma; Humans; Hyperammonemia; Hypnotics and Sedatives; Intraoperative Complications; Language; Levetiracetam; Male; Middle Aged; Piperidines; Piracetam; Propofol; Remifentanil; Seizures; Temporal Lobe; Valproic Acid	2015
[Clinical misdiagnosis analysis of valproate encephalopathy]. Zhonghua yi xue za zhi, 2014, Sep-09, Volume: 94, Issue:33 Topics: Anticonvulsants; Brain Diseases; Brain Edema; Brain Neoplasms; Diagnostic Errors; Epilepsy; Humans; Intracranial Hemorrhages; Valproic Acid; Vascular Diseases; Vasoconstriction	2014
Reversible weakness and encephalopathy while on long-term valproate treatment due to carnitine deficiency. BMJ case reports, 2015, Sep-02, Volume: 2015 Topics: Adult; Antimanic Agents; Brain Diseases; Cardiomyopathies; Carnitine; Female; Humans; Hyperammonemia; Muscle Weakness; Muscular Diseases; Psychotic Disorders; Treatment Outcome; Valproic Acid	2015
Effect of valproic acid combined with therapeutic hypothermia on neurologic outcome in asphyxial cardiac arrest model of rats. The American journal of emergency medicine, 2015, Volume: 33, Issue:12 Topics: Animals; Asphyxia; Brain Diseases; Combined Modality Therapy; Disease Models, Animal; Enzyme Inhibitors; Heart Arrest; Hippocampus; Hypothermia, Induced; Male; Rats; Rats, Sprague-Dawley; Valproic Acid	2015
[Valproate can induce reversible encephalopathy]. Ugeskrift for laeger, 2015, May-11, Volume: 177, Issue:20 Topics: Aged; Anticonvulsants; Brain Diseases; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Neurotoxicity Syndromes; Valproic Acid	2015
Valproate-induced hyperammonemic encephalopathy associated with urinary tract infection and urinary retention in the psychiatric setting. The Australian and New Zealand journal of psychiatry, 2016, Volume: 50, Issue:11 Topics: Antimanic Agents; Bipolar Disorder; Brain Diseases; Humans; Hyperammonemia; Male; Middle Aged; Urinary Retention; Urinary Tract Infections; Valproic Acid	2016
A case with hyperammonemic encephalopathy triggered by single dose valproate. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2016, Volume: 37, Issue:12 Topics: Attention Deficit Disorder with Hyperactivity; Brain Diseases; Female; GABA Agents; Humans; Hyperammonemia; Magnetic Resonance Imaging; Valproic Acid; Young Adult	2016
Valproate-induced encephalopathy in a comorbid elderly woman. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2017, Volume: 17, Issue:3 Topics: Anticonvulsants; Brain Diseases; Comorbidity; Female; Humans; Hyperammonemia; Lethargy; Middle Aged; Polypharmacy; Psychotic Disorders; Valproic Acid	2017
Reversible Encephalopathy due to Valproic Acid Induced Hyperammonemia in a Patient with Bipolar I Disorder: A Cautionary Report. Psychopharmacology bulletin, 2017, 01-26, Volume: 47, Issue:1 Topics: Antimanic Agents; Bipolar Disorder; Brain Diseases; Female; Humans; Hyperammonemia; Middle Aged; Valproic Acid	2017
Valproate-induced hyperammonemic encephalopathy treated by hemodialysis. Renal failure, 2008, Volume: 30, Issue:8 Topics: Adolescent; Anticonvulsants; Brain Diseases; Female; Humans; Hyperammonemia; Renal Dialysis; Valproic Acid	2008
Subacute encephalopathy and seizures in alcoholics (SESA) presenting with non-convulsive status epilepticus. Seizure, 2011, Volume: 20, Issue:6 Topics: Acetamides; Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Brain Diseases; Confusion; Diffusion Magnetic Resonance Imaging; Electroencephalography; Female; Humans; Lacosamide; Lorazepam; Middle Aged; Neurologic Examination; Paresis; Patient Compliance; Phenytoin; Seizures; Status Epilepticus; Tomography, X-Ray Computed; Valproic Acid	2011
Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery. Molecular pharmaceutics, 2011, Oct-03, Volume: 8, Issue:5 Topics: Algorithms; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Diseases; Central Nervous System Agents; Drug Design; Drug Stability; Gas Chromatography-Mass Spectrometry; Infusions, Intra-Arterial; Isomerism; Large Neutral Amino Acid-Transporter 1; Male; Molecular Structure; Phenylalanine; Prodrugs; Rats; Spectrometry, Mass, Electrospray Ionization; Valproic Acid	2011
Unilateral basal-ganglia involvement likely due to valproate-induced hyperammonemic encephalopathy. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:4 Topics: Anticonvulsants; Basal Ganglia; Brain Diseases; Child, Preschool; Diffusion Magnetic Resonance Imaging; Functional Laterality; Humans; Hyperammonemia; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Seizures; Valproic Acid	2012
Topiramate increases the risk of valproic acid-induced encephalopathy. Epilepsia, 2013, Volume: 54, Issue:1 Topics: Adult; Aged; Anticonvulsants; Brain Diseases; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Female; Fructose; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Topiramate; Valproic Acid; Young Adult	2013
[Reversible encephalopathy caused by valproic acid in an adolescent with idiopathic generalised epilepsy]. Revista de neurologia, 2012, Dec-01, Volume: 55, Issue:11 Topics: Adolescent; Anticonvulsants; Brain Diseases; Epilepsy, Generalized; Humans; Male; Valproic Acid	2012
A case of nonconvulsive status epilepticus associated with focal cortical dysplasia. Brain & development, 2003, Volume: 25, Issue:3 Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain Diseases; Cerebral Cortex; Child; Child, Preschool; Clobazam; Electroencephalography; Female; Humans; Infant; Magnetic Resonance Imaging; Pyridoxal Phosphate; Radiography; Status Epilepticus; Valproic Acid	2003
Ultrastructure of astrocytes in the cortex of the hippocampal gyrus and in the neocortex of the temporal lobe in experimental valproate encephalopathy and after valproate withdrawal. International journal of experimental pathology, 2003, Volume: 84, Issue:3 Topics: Animals; Anticonvulsants; Astrocytes; Behavior, Animal; Brain Diseases; Male; Microscopy, Electron; Neocortex; Parahippocampal Gyrus; Rats; Rats, Wistar; Valproic Acid	2003
Hyperammonemic encephalopathy induced by a combination of valproate and pivmecillinam. Acta neurologica Scandinavica, 2004, Volume: 109, Issue:4 Topics: Aged; Amdinocillin Pivoxil; Anti-Bacterial Agents; Anticonvulsants; Brain Diseases; Female; Humans; Hyperammonemia; Valproic Acid	2004
Encephalopathy and myoclonus triggered by valproic acid. Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:6 Topics: Adult; Antimanic Agents; Brain Diseases; Electroencephalography; Humans; Male; Myoclonus; Valproic Acid	2004
Valproic acid-associated hyperammonemic encephalopathy: a case report from the psychiatric setting. International clinical psychopharmacology, 2005, Volume: 20, Issue:1 Topics: Antimanic Agents; Bipolar Disorder; Brain Diseases; Confusion; Female; Humans; Hyperammonemia; Middle Aged; Tremor; Unconsciousness; Valproic Acid	2005
Topiramate-valproate-induced hyperammonemic encephalopathy syndrome: case report. Journal of child neurology, 2005, Volume: 20, Issue:2 Topics: Adolescent; Anticonvulsants; Brain Diseases; Chromosome Inversion; Chromosomes, Human, Pair 15; Drug Therapy, Combination; Epilepsy; Fructose; Humans; Hyperammonemia; Male; Syndrome; Topiramate; Valproic Acid	2005
Valproate-induced encephalopathy. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005, Volume: 15, Issue:9 Topics: Aged; Anticonvulsants; Brain Diseases; Electroencephalography; Female; Humans; Valproic Acid	2005
[Valproate-caused encephalopathy]. Ugeskrift for laeger, 2005, Oct-03, Volume: 167, Issue:40 Topics: Aged; Anticonvulsants; Brain Diseases; Humans; Male; Mental Status Schedule; Neurotoxicity Syndromes; Valproic Acid	2005
Valproic acid induced encephalopathy--19 new cases in Germany from 1994 to 2003--a side effect associated to VPA-therapy not only in young children. Seizure, 2006, Volume: 15, Issue:6 Topics: Adolescent; Aged; Anticonvulsants; Brain Diseases; Child, Preschool; Female; Humans; Hyperammonemia; Infant; Male; Middle Aged; Neurotoxicity Syndromes; Surveys and Questionnaires; Valproic Acid	2006
Parietal lobe source localization and sensitivity to hyperventilation in a patient with subclinical rhythmic electrographic discharges of adults (SREDA). Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2006, Volume: 117, Issue:10 Topics: Aged; Anticonvulsants; Brain Diseases; Electroencephalography; Humans; Hyperventilation; Magnetic Resonance Imaging; Male; Parietal Lobe; Valproic Acid	2006
Valproate-induced chorea and encephalopathy in atypical nonketotic hyperglycinemia. Pediatric neurology, 2006, Volume: 35, Issue:5 Topics: Anticonvulsants; Brain Diseases; Child; Chorea; Female; Humans; Hyperglycinemia, Nonketotic; Valproic Acid	2006
[Experimental study on the possibility of brain damage induced by chronic treatment with phenobarbital, clonazepam, valproic acid and topiramate in immature rats]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2007, Volume: 45, Issue:2 Topics: Age Factors; Animals; Anticonvulsants; Apoptosis; bcl-2-Associated X Protein; Brain; Brain Diseases; Clonazepam; Microscopy, Electron, Transmission; Neurons; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Valproic Acid	2007
Hyperammonemia and valproic acid-induced encephalopathy. The American journal of psychiatry, 2007, Volume: 164, Issue:12 Topics: Brain Diseases; Humans; Hyperammonemia; Protein Binding; Valproic Acid	2007
Encephalopathy induced by levetiracetam added to valproate. Acta neurologica Scandinavica, 2008, Volume: 117, Issue:5 Topics: Adult; Anticonvulsants; Brain Diseases; Electroencephalography; Epilepsy; Humans; Levetiracetam; Male; Piracetam; Valproic Acid	2008
[Valproate-associated hyperammonemic encephalopathy. Report of one case]. Revista medica de Chile, 2007, Volume: 135, Issue:11 Topics: Aged; Anticonvulsants; Brain Diseases; Female; Humans; Hyperammonemia; Valproic Acid	2007
Secondary hyperammonaemia: a possible mechanism for valproate encephalopathy. Lancet (London, England), 1980, Jun-14, Volume: 1, Issue:8181 Topics: Ammonia; Brain; Brain Diseases; Child, Preschool; Epilepsy; Female; Humans; Propionates; Valproic Acid	1980
Treatment of epileptic patients with valproic acid does not modify plasma and urine short-chain-fatty acids. Acta neurologica Scandinavica, 1983, Volume: 68, Issue:4 Topics: Adolescent; Adult; Ammonia; Brain Diseases; Butyrates; Epilepsy; Fatty Acids; Female; Hemiterpenes; Humans; Isobutyrates; Male; Pentanoic Acids; Propionates; Reye Syndrome; Valerates; Valproic Acid	1983
Sodium valproate-induced hyperammonemia without clinical hepatic dysfunction. Neurology, 1982, Volume: 32, Issue:2 Topics: Adult; Ammonia; Brain Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Female; Humans; Liver Function Tests; Male; Middle Aged; Valproic Acid	1982
[Liver involvement and encephalopathy in a child during sodium valproate therapy]. Ugeskrift for laeger, 1982, Jan-11, Volume: 144, Issue:2 Topics: Brain Diseases; Chemical and Drug Induced Liver Injury; Child, Preschool; Female; Humans; Valproic Acid	1982
[Description of a case of a syndrome similar to Reye's syndrome in a male adult undergoing treatment with valproic acid and phenobarbital]. Giornale di clinica medica, 1982, Volume: 63, Issue:9 Topics: Adult; Brain Diseases; Coma; Epilepsy, Tonic-Clonic; Fever; Humans; Male; Muscle Rigidity; Phenobarbital; Reye Syndrome; Valproic Acid; Vomiting	1982
Reversible dementia and apparent brain atrophy during valproate therapy. Annals of neurology, 1995, Volume: 38, Issue:4 Topics: Atrophy; Brain Diseases; Child; Child, Preschool; Dementia; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Male; Valproic Acid	1995
Valproate encephalopathy and hypocarnitinaemia in diabetic patients. Journal of neurology, 1994, Volume: 241, Issue:9 Topics: Adolescent; Adult; Brain Diseases; Carnitine; Diabetes Mellitus, Type 1; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Valproic Acid	1994
West syndrome associated with porencephaly. Pediatric neurosurgery, 1994, Volume: 21, Issue:3 Topics: Adrenocorticotropic Hormone; Brain Diseases; Child, Preschool; Clonazepam; Comorbidity; Cysts; Electroencephalography; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Nitrazepam; Spasms, Infantile; Treatment Outcome; Valproic Acid	1994
Fatal fulminant hepatic failure due to sodium valproate in an adolescent. Indian pediatrics, 1994, Volume: 31, Issue:2 Topics: Adolescent; Brain Diseases; Drug Therapy, Combination; Fatal Outcome; Hepatic Encephalopathy; Humans; Jaundice; Liver; Male; Mannitol; Necrosis; Neomycin; Phenobarbital; Valproic Acid	1994
Pharmacodynamic interactions between phenytoin and valproate: individual and combined antiepileptic and neurotoxic actions in mice. Clinical neuropharmacology, 1994, Volume: 17, Issue:1 Topics: Animals; Brain; Brain Diseases; Drug Interactions; Drug Synergism; Electroshock; Epilepsy; Female; Mice; Phenytoin; Valproic Acid	1994
[Encephalopathy associated with hyperammonemia in an alcoholic patient treated with sodium valproate]. Gastroenterologie clinique et biologique, 1993, Volume: 17, Issue:6-7 Topics: Ammonia; Brain Diseases; Drug Therapy, Combination; Humans; Male; Middle Aged; Phenobarbital; Psychoses, Alcoholic; Valproic Acid	1993
Lamotrigine encephalopathy. Lancet (London, England), 1996, Apr-06, Volume: 347, Issue:9006 Topics: Anticonvulsants; Astrocytoma; Brain Diseases; Brain Neoplasms; Drug Interactions; Female; Frontal Lobe; Humans; Lamotrigine; Middle Aged; Seizures; Triazines; Valproic Acid	1996
A case of West syndrome with atypical massive gray matter heterotopia that is well controlled by ACTH therapy. Acta paediatrica Japonica : Overseas edition, 1996, Volume: 38, Issue:3 Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain; Brain Diseases; Choristoma; Clonazepam; Drug Therapy, Combination; Electroencephalography; Female; Humans; Infant; Spasms, Infantile; Tomography, X-Ray Computed; Valproic Acid	1996
Morphological features of encephalopathy after chronic administration of the antiepileptic drug valproate to rats. A transmission electron microscopic study of capillaries in the cerebellar cortex. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1996, Volume: 48, Issue:1 Topics: Animals; Brain Diseases; Capillaries; Cerebellum; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Microscopy, Electron; Neuroglia; Rats; Rats, Wistar; Valproic Acid	1996
[Clinical workload at the outpatient neuropediatric clinic]. Revista de neurologia, 1997, Volume: 25, Issue:138 Topics: Adolescent; Ambulatory Care; Brain Diseases; Child; Child, Preschool; Electroencephalography; Female; Health Services; Humans; Incidence; Infant; Infant, Newborn; Information Systems; Male; Neurology; Pediatrics; Phenobarbital; Prevalence; Spain; Valproic Acid	1997
Reversible pseudoatrophy of the brain and mental deterioration associated with valproate treatment. Epilepsia, 1998, Volume: 39, Issue:1 Topics: Atrophy; Brain; Brain Diseases; Child; Cognition Disorders; Diagnosis, Differential; Electroencephalography; Epilepsy; Female; Humans; Intellectual Disability; Intelligence Tests; Magnetic Resonance Imaging; Prospective Studies; Retrospective Studies; Valproic Acid; Wechsler Scales	1998
Fatal hyperammonemia in a patient with systemic lupus erythematosus. Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:8 Topics: Adult; Ammonia; Anticonvulsants; Brain Diseases; Fatal Outcome; Female; Humans; Kidney Failure, Chronic; Lupus Erythematosus, Systemic; Nephrotic Syndrome; Risk Factors; Seizures; Valproic Acid	1998
[Encephalopathies caused by valproate]. Fortschritte der Neurologie-Psychiatrie, 1999, Volume: 67, Issue:1 Topics: Adult; Ammonia; Anticonvulsants; Brain Diseases; Drug Interactions; Epilepsy; Humans; Middle Aged; Valproic Acid	1999
Valproate-induced hyperammonemic encephalopathy in the presence of topiramate. Neurology, 2000, Jan-11, Volume: 54, Issue:1 Topics: Adult; Ammonia; Anticonvulsants; Brain Diseases; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Fructose; Humans; Male; Topiramate; Valproic Acid	2000
[A case report of valproate encephalopathy]. Rinsho shinkeigaku = Clinical neurology, 1999, Volume: 39, Issue:10 Topics: Adult; Ammonia; Anticonvulsants; Biomarkers; Brain; Brain Diseases; Carnitine; Epilepsy; Female; Humans; Mitochondria; Valproic Acid	1999
Latent coeliac disease in a child with epilepsy, cerebral calcifications, drug-induced systemic lupus erythematosus and intestinal folic acid malabsorption associated with impairment of folic acid transport across the blood-brain barrier. European journal of pediatrics, 2001, Volume: 160, Issue:5 Topics: Adolescent; Anticonvulsants; Biological Transport; Blood-Brain Barrier; Brain; Brain Diseases; Calcinosis; Celiac Disease; Epilepsy; Ethosuximide; Folic Acid; Humans; Lupus Erythematosus, Systemic; Male; Urea; Valproic Acid	2001
[Encephalopathy induced by ingestion of ammonium during valproate therapy]. Gastroenterologie clinique et biologique, 2001, Volume: 25, Issue:3 Topics: Brain Diseases; Diet; Drug Interactions; Female; Humans; Hyperammonemia; Middle Aged; Quaternary Ammonium Compounds; Valproic Acid	2001
Valproate-induced encephalopathy. Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 2001, Volume: 64, Issue:8 Topics: Ammonia; Anticonvulsants; Brain Diseases; Electroencephalography; Female; Humans; Middle Aged; Valproic Acid	2001
Ultrastructure of Purkinje cell perikarya and their dendritic processes in the rat cerebellar cortex in experimental encephalopathy induced by chronic application of valproate. International journal of experimental pathology, 2001, Volume: 82, Issue:6 Topics: Animals; Anticonvulsants; Brain Diseases; Cerebellar Cortex; Dendrites; Drug Administration Schedule; Male; Microscopy, Electron; Purkinje Cells; Rats; Rats, Wistar; Valproic Acid	2001
Serum and CSF glutamine levels in valproate-related hyperammonemic encephalopathy. Epilepsia, 2002, Volume: 43, Issue:2 Topics: Adolescent; Adult; Ammonia; Anticonvulsants; Brain; Brain Diseases; Electroencephalography; Female; Glutamine; Humans; Hyperammonemia; Male; Middle Aged; Valproic Acid	2002
Morphometric analysis of the cerebellar cortex capillaries in the course of experimental valproate encephalopathy and after chronic exposure to sodium valproate using transmission electron microscopy. Folia neuropathologica, 2001, Volume: 39, Issue:4 Topics: Animals; Anticonvulsants; Brain Diseases; Capillaries; Cerebellar Cortex; Cerebrovascular Circulation; Male; Microscopy, Electron; Rats; Rats, Wistar; Valproic Acid	2001
Acute intoxication with sodium valproate. Annals of neurology, 1979, Volume: 6, Issue:6 Topics: Acute Disease; Adolescent; Adult; Brain Diseases; Epilepsy; Female; Humans; Male; Valproic Acid	1979
Posthypoxic action myoclonus: review of the literature and report of two new cases with response to valproate and estrogen. Advances in neurology, 1979, Volume: 26 Topics: Adult; Brain Diseases; Estrogens, Conjugated (USP); Female; Humans; Hypoxia; Hypoxia, Brain; Male; Middle Aged; Myoclonus; Valproic Acid	1979
Sodium valproate: serial monitoring of EEG and serum levels. Neurology, 1979, Volume: 29, Issue:11 Topics: Adolescent; Adult; Brain Diseases; Electroencephalography; Female; Humans; Middle Aged; Seizures; Valproic Acid	1979
[Multiple system atrophy with macro square wave jerks and pendular nystagmus]. Rinsho shinkeigaku = Clinical neurology, 1992, Volume: 32, Issue:11 Topics: Atrophy; Baclofen; Brain Diseases; Diazepam; Electrooculography; Eye Movements; Female; Humans; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Saccades; Valproic Acid	1992
Abnormal metabolism of carnitine and valproate in a case of acute encephalopathy during chronic valproate therapy. Brain & development, 1992, Volume: 14, Issue:3 Topics: Brain Diseases; Carnitine; Cerebral Palsy; Child; Chronic Disease; Female; Gas Chromatography-Mass Spectrometry; Humans; Oxidation-Reduction; Seizures; Valproic Acid	1992
Cerebral edema following acute sodium valproate overdose. Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:2 Topics: Adult; Brain Diseases; Drug Overdose; Edema; Humans; Hypocalcemia; Kidney; Liver; Male; Valproic Acid	1992
State of stupor from valproic acid during chronic treatment: case report. Italian journal of neurological sciences, 1991, Volume: 12, Issue:2 Topics: Adult; Brain Diseases; Carbamazepine; Clonazepam; Electroencephalography; Epilepsies, Myoclonic; Female; Humans; Unconsciousness; Valproic Acid	1991
Myoclonus: a manifestation of neurocysticercosis. Postgraduate medical journal, 1991, Volume: 67, Issue:783 Topics: Brain Diseases; Child; Cysticercosis; Female; Humans; Myoclonus; Praziquantel; Valproic Acid	1991
Role of the substantia nigra in GABA-mediated anticonvulsant actions. Advances in neurology, 1986, Volume: 44 Topics: Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Diseases; Denervation; Disease Susceptibility; Efferent Pathways; gamma-Aminobutyric Acid; Humans; Injections; Mesencephalon; Nerve Endings; Nerve Tissue Proteins; Reaction Time; Seizures; Substantia Nigra; Synaptic Transmission; Valproic Acid; Vigabatrin	1986
Effect of sodium valproate (VPA) on cerebral amino acids: mechanism of gamma-aminobutyric acid (GABA) elevation and possible causal relation of VPA-induced encephalopathy and glutamine level. Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:9 Topics: Amino Acids; Animals; Brain Chemistry; Brain Diseases; gamma-Aminobutyric Acid; Glutamine; Male; Mice; Mice, Inbred Strains; Valproic Acid	1988
[Encephalopathy with asterixis induced by sodium valproate. Role of hyperammonemia without hepatic insufficiency]. Presse medicale (Paris, France : 1983), 1985, Feb-16, Volume: 14, Issue:7 Topics: Ammonia; Brain Diseases; Humans; Male; Middle Aged; Movement Disorders; Valproic Acid	1985
Sodium valproate "encephalopathy": report of three cases with generalised epilepsy. Italian journal of neurological sciences, 1985, Volume: 6, Issue:1 Topics: Adult; Arousal; Brain Diseases; Child; Confusion; Electroencephalography; Epilepsy; Female; Humans; Male; Valproic Acid	1985
[A clinico-biochemical study of acute encephalopathy in patients treated with Ca-hopantenate]. No to hattatsu = Brain and development, 1985, Volume: 17, Issue:5 Topics: Acute Disease; Adolescent; Adult; Age Factors; Blood Chemical Analysis; Brain Diseases; Child; Child, Preschool; Female; gamma-Aminobutyric Acid; Humans; Infant; Male; Pantothenic Acid; Reye Syndrome; Valproic Acid	1985