Page last updated: 2024-10-26

valproic acid and Bowel Incontinence

valproic acid has been researched along with Bowel Incontinence in 2 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Omar, MI1
Alexander, CE1
Kusunoki, M1
Shoji, Y1
Ikeuchi, H1
Yamagata, K1
Yamamura, T1
Utsunomiya, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) Versus Psyllium (Agio®) for the Treatment of Fecal Incontinence: Multicenter Randomized Trial (SERAFI)[NCT06166615]Phase 2/Phase 3148 participants (Anticipated)Interventional2023-12-15Not yet recruiting
Phase 1 Treatment Study to Assess Safety and Proof of Concept to Assess Potential Efficacy of the Implanted Internal Anal Sphincter BioSphincterTM Bioengineered From Autologous Cells to Treat Patients With Severe Passive Fecal Incontinence[NCT05616208]Phase 110 participants (Anticipated)Interventional2022-11-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for valproic acid and Bowel Incontinence

ArticleYear
Drug treatment for faecal incontinence in adults.
    The Cochrane database of systematic reviews, 2013, Jun-11, Issue:6

    Topics: Adult; Antidiarrheals; Diarrhea; Epinephrine; Fecal Incontinence; Gastrointestinal Agents; Humans; L

2013
Drug treatment for faecal incontinence in adults.
    The Cochrane database of systematic reviews, 2013, Jun-11, Issue:6

    Topics: Adult; Antidiarrheals; Diarrhea; Epinephrine; Fecal Incontinence; Gastrointestinal Agents; Humans; L

2013
Drug treatment for faecal incontinence in adults.
    The Cochrane database of systematic reviews, 2013, Jun-11, Issue:6

    Topics: Adult; Antidiarrheals; Diarrhea; Epinephrine; Fecal Incontinence; Gastrointestinal Agents; Humans; L

2013
Drug treatment for faecal incontinence in adults.
    The Cochrane database of systematic reviews, 2013, Jun-11, Issue:6

    Topics: Adult; Antidiarrheals; Diarrhea; Epinephrine; Fecal Incontinence; Gastrointestinal Agents; Humans; L

2013

Trials

1 trial available for valproic acid and Bowel Incontinence

ArticleYear
Usefulness of valproate sodium for treatment of incontinence after ileoanal anastomosis.
    Surgery, 1990, Volume: 107, Issue:3

    Topics: Adult; Anal Canal; Anastomosis, Surgical; Fecal Incontinence; Female; Humans; Ileum; Male; Middle Ag

1990