valproic acid has been researched along with Bone Loss, Osteoclastic in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine bone development in children and adolescents who have uncomplicated idiopathic epilepsy and had received monotherapy with carbamazepine or valproic acid for at least 1 year." | 3.71 | Analysis of the musculoskeletal system in children and adolescents receiving anticonvulsant monotherapy with valproic acid or carbamazepine. ( Herkenrath, P; Rauch, F; Rieger-Wettengl, G; Schauseil-Zipf, U; Schoenau, E; Stabrey, A; Tutlewski, B, 2001) |
| "Epilepsy is a major public health problem affecting nearly 50 million people world wide." | 1.35 | Fish liver oil and propolis as protective natural products against the effect of the anti-epileptic drug valproate on immunological markers of bone formation in rats. ( El Elshamy, KA; Elwakkad, AS; Sibaii, H, 2008) |
| "The % of gingival hyperplasia was significantly higher (P less than 0." | 1.27 | The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients. ( Seymour, RA; Smith, DG; Turnbull, DN, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elwakkad, AS | 1 |
| El Elshamy, KA | 1 |
| Sibaii, H | 1 |
| Rieger-Wettengl, G | 1 |
| Tutlewski, B | 1 |
| Stabrey, A | 1 |
| Rauch, F | 1 |
| Herkenrath, P | 1 |
| Schauseil-Zipf, U | 1 |
| Schoenau, E | 1 |
| Seymour, RA | 1 |
| Smith, DG | 1 |
| Turnbull, DN | 1 |
3 other studies available for valproic acid and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Fish liver oil and propolis as protective natural products against the effect of the anti-epileptic drug valproate on immunological markers of bone formation in rats.
Topics: Alkaline Phosphatase; Animals; Anticonvulsants; Atropine; Biomarkers; Bone Resorption; Disease Model | 2008 |
Analysis of the musculoskeletal system in children and adolescents receiving anticonvulsant monotherapy with valproic acid or carbamazepine.
Topics: Adolescent; Alkaline Phosphatase; Amino Acids; Anticonvulsants; Biomarkers; Bone Density; Bone Resor | 2001 |
The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients.
Topics: Adolescent; Adult; Aged; Alveolar Process; Bone Resorption; Cross-Sectional Studies; Dental Plaque I | 1985 |