valproic acid has been researched along with Bone Diseases, Developmental in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Bone Diseases, Developmental: Diseases resulting in abnormal GROWTH or abnormal MORPHOGENESIS of BONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether long-term treatment with valproate (VPA) and/or lamotrigine (LTG) in children with epilepsy is associated with altered growth and/or bone metabolism." | 7.71 | Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy. ( Atkinson, SA; Guo, CY; Ronen, GM, 2001) |
| "To determine whether long-term treatment with valproate (VPA) and/or lamotrigine (LTG) in children with epilepsy is associated with altered growth and/or bone metabolism." | 3.71 | Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy. ( Atkinson, SA; Guo, CY; Ronen, GM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, HS | 1 |
| Wang, SY | 1 |
| Salter, DM | 1 |
| Wang, CC | 1 |
| Chen, SJ | 1 |
| Fan, HC | 1 |
| Guo, CY | 1 |
| Ronen, GM | 1 |
| Atkinson, SA | 1 |
2 other studies available for valproic acid and Bone Diseases, Developmental
| Article | Year |
|---|---|
The impact of the use of antiepileptic drugs on the growth of children.
Topics: Adolescent; Anticonvulsants; Body Height; Bone Diseases, Developmental; Calcium; Carbamazepine; Cell | 2013 |
Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Bone and Bones; Bone Density; Bone Diseases, Developmental; Bone Diseas | 2001 |