valproic acid has been researched along with Blood Loss, Surgical in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Blood Loss, Surgical: Loss of blood during a surgical procedure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid (VPA) has been associated with coagulation factors deficiency, platelet dysfunction and hemorrhagic complications." | 1.43 | Valproic acid as an antiepileptic drug: Is there a clinical relevance for the epilepsy surgeon? ( Arora, A; Chandra, PS; Garg, K; Kurwale, N; Tripathi, M, 2016) |
| "We compared the estimated surgical blood loss and the estimated change in red blood cell (RBC) volume between groups by unpaired t tests." | 1.29 | Preoperative valproate administration does not increase blood loss during temporal lobectomy. ( Barbaro, NM; Laxer, KD; Rampil, IJ; Ward, MM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurwale, N | 1 |
| Garg, K | 1 |
| Arora, A | 1 |
| Chandra, PS | 1 |
| Tripathi, M | 1 |
| Ward, MM | 1 |
| Barbaro, NM | 1 |
| Laxer, KD | 1 |
| Rampil, IJ | 1 |
| Winter, SL | 1 |
| Kriel, RL | 1 |
| Novacheck, TF | 1 |
| Luxenberg, MG | 1 |
| Leutgeb, VJ | 1 |
| Erickson, PA | 1 |
| Gil-Fernández, JJ | 1 |
1 review available for valproic acid and Blood Loss, Surgical
| Article | Year |
|---|---|
Perioperative blood loss: the effect of valproate.
Topics: Adolescent; Blood Component Transfusion; Blood Loss, Surgical; Blood Transfusion; Cerebral Palsy; Ch | 1996 |
3 other studies available for valproic acid and Blood Loss, Surgical
| Article | Year |
|---|---|
Valproic acid as an antiepileptic drug: Is there a clinical relevance for the epilepsy surgeon?
Topics: Adolescent; Anticonvulsants; Blood Loss, Surgical; Clinical Decision-Making; Drug Resistant Epilepsy | 2016 |
Preoperative valproate administration does not increase blood loss during temporal lobectomy.
Topics: Adult; Anticonvulsants; Blood Loss, Surgical; Blood Transfusion; Epilepsy, Temporal Lobe; Erythrocyt | 1996 |
Analysis of surgical blood loss and number of blood transfusions after temporal lobe resection performed in adults with epilepsy receiving valproate (VPA) in the immediate preoperative period.
Topics: Adolescent; Adult; Aged; Bleeding Time; Blood Loss, Surgical; Blood Transfusion; Epilepsy, Temporal | 1997 |