Page last updated: 2024-10-26

valproic acid and Blood Loss, Postoperative

valproic acid has been researched along with Blood Loss, Postoperative in 2 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Valproic acid (VPA) is an antiepileptic drug frequently used in children."1.34Severe bleeding complications during antiepileptic treatment with valproic acid in children. ( Albisetti, M; Cannizzaro, E; Schmugge, M; Wohlrab, G, 2007)
"We compared the estimated surgical blood loss and the estimated change in red blood cell (RBC) volume between groups by unpaired t tests."1.29Preoperative valproate administration does not increase blood loss during temporal lobectomy. ( Barbaro, NM; Laxer, KD; Rampil, IJ; Ward, MM, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cannizzaro, E1
Albisetti, M1
Wohlrab, G1
Schmugge, M1
Ward, MM1
Barbaro, NM1
Laxer, KD1
Rampil, IJ1

Other Studies

2 other studies available for valproic acid and Blood Loss, Postoperative

ArticleYear
Severe bleeding complications during antiepileptic treatment with valproic acid in children.
    Neuropediatrics, 2007, Volume: 38, Issue:1

    Topics: Adolescent; Anticonvulsants; Blood Platelet Disorders; Child, Preschool; Epilepsy; Humans; Infant; I

2007
Preoperative valproate administration does not increase blood loss during temporal lobectomy.
    Epilepsia, 1996, Volume: 37, Issue:1

    Topics: Adult; Anticonvulsants; Blood Loss, Surgical; Blood Transfusion; Epilepsy, Temporal Lobe; Erythrocyt

1996