valproic acid has been researched along with Blastocyst Disintegration in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the current study, we wanted to extend our findings and test the hypothesis that Folbp2(-/-) mice are more susceptible to the teratogenic effects of valproic acid (VPA), a commonly used antiepileptic drug that is known to induce neural tube defects (NTDs) in both humans and laboratory animals." | 3.72 | Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice. ( Finnell, RH; Merriweather, MY; Spiegelstein, O; Wicker, NJ, 2003) |
| "Valproic acid (VPA) is an anticonvulsant drug that is widely used therapeutically for a variety of neurological conditions." | 1.33 | Myo-inositol enhances teratogenicity of valproic acid in the mouse. ( Finnell, RH; Giavini, E; Massa, V; Wlodarczyk, B, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spiegelstein, O | 1 |
| Merriweather, MY | 1 |
| Wicker, NJ | 1 |
| Finnell, RH | 2 |
| Massa, V | 1 |
| Wlodarczyk, B | 1 |
| Giavini, E | 1 |
2 other studies available for valproic acid and Blastocyst Disintegration
| Article | Year |
|---|---|
Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carrier Proteins; Diet; Disease Models, Anima | 2003 |
Myo-inositol enhances teratogenicity of valproic acid in the mouse.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Anticonvulsants; Drug Synergism; Embryo | 2006 |