Page last updated: 2024-10-26

valproic acid and Birth Weight

valproic acid has been researched along with Birth Weight in 12 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Birth Weight: The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Prenatal exposure to valproic acid (VPA) induces behavioral disorders and enhancement of oxido-inflammatory stress in Autism Spectrum Disorders (ASDs)."7.88Hesperetin and it nanocrystals ameliorate social behavior deficits and oxido-inflammatory stress in rat model of autism. ( Hajizadeh Moghaddam, A; Khalaj, R; Zare, M, 2018)
"Prenatal exposure to valproic acid (VPA) induces behavioral disorders and enhancement of oxido-inflammatory stress in Autism Spectrum Disorders (ASDs)."3.88Hesperetin and it nanocrystals ameliorate social behavior deficits and oxido-inflammatory stress in rat model of autism. ( Hajizadeh Moghaddam, A; Khalaj, R; Zare, M, 2018)
"The effects of antiepileptic drugs (AED) on infants during pregnancy and delivery were studied in a total of 82 epileptic mothers on various monotherapies; 29 cases receiving valproic acid (VPA), 20 receiving phenytoin (PHT), 18 on carbamazepine (CBZ) and 15 on phenobarbital (PB)."3.68[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital]. ( Ishikawa, S; Izumi, M; Okada, H; Takeda, A; Tanaka, H, 1991)
"From a series of 1,713 patients with craniosynostosis hospitalized between 1976 and 1996, 237 propositi with metopic synostosis were analyzed."1.30Syndromal and nonsyndromal primary trigonocephaly: analysis of a series of 237 patients. ( Lajeunie, E; Le Merrer, M; Marchac, D; Renier, D, 1998)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's4 (33.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khalaj, R1
Hajizadeh Moghaddam, A1
Zare, M1
Veiby, G2
Daltveit, AK2
Engelsen, BA2
Gilhus, NE2
Harden, CL2
Meador, KJ2
Pennell, PB2
Hauser, WA2
Gronseth, GS2
French, JA2
Wiebe, S2
Thurman, D2
Koppel, BS2
Kaplan, PW2
Robinson, JN2
Hopp, J2
Ting, TY2
Gidal, B2
Hovinga, CA2
Wilner, AN2
Vazquez, B2
Holmes, L2
Krumholz, A2
Finnell, R2
Hirtz, D2
Le Guen, C2
Costa-Borges, N1
Gonzalez, S1
Santaló, J1
Ibáñez, E1
Vajda, FJ1
Hitchcock, A1
Graham, J1
O'Brien, T1
Lander, C1
Eadie, M1
Martin, PJ1
Millac, PA1
Lajeunie, E1
Le Merrer, M1
Marchac, D1
Renier, D1
Yerby, MS1
Leavitt, A1
Erickson, DM1
McCormick, KB1
Loewenson, RB1
Sells, CJ1
Benedetti, TJ1
Tanaka, H1
Takeda, A1
Izumi, M1
Okada, H1
Ishikawa, S1
Collins, MD1
Fradkin, R1
Scott, WJ1

Reviews

2 reviews available for valproic acid and Birth Weight

ArticleYear
Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee
    Neurology, 2009, Jul-14, Volume: 73, Issue:2

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Birth Weight; Cognition Disorders; Contraindications;

2009
Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurolo
    Epilepsia, 2009, Volume: 50, Issue:5

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Birth Weight; Cognition Disorders; Contraindications;

2009

Other Studies

10 other studies available for valproic acid and Birth Weight

ArticleYear
Hesperetin and it nanocrystals ameliorate social behavior deficits and oxido-inflammatory stress in rat model of autism.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2018, Volume: 69

    Topics: Animals; Anticonvulsants; Antioxidants; Autistic Disorder; Birth Weight; Brain Chemistry; Cytokines;

2018
Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy.
    Journal of neurology, 2014, Volume: 261, Issue:3

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Cohort Studies; Epilepsy; Female;

2014
Pregnancy, delivery, and outcome for the child in maternal epilepsy.
    Epilepsia, 2009, Volume: 50, Issue:9

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Apgar Score; Birth Weight; Congenital Abnormali

2009
Effect of the enucleation procedure on the reprogramming potential and developmental capacity of mouse cloned embryos treated with valproic acid.
    Reproduction (Cambridge, England), 2011, Volume: 141, Issue:6

    Topics: Acetylation; Analysis of Variance; Animals; Birth Weight; Blastocyst; Cell Line; Cellular Reprogramm

2011
The Australian Register of Antiepileptic Drugs in Pregnancy: the first 1002 pregnancies.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2007, Volume: 47, Issue:6

    Topics: Anticonvulsants; Australia; Birth Weight; Epilepsy; Female; Fetus; Humans; Pregnancy; Pregnancy Comp

2007
Pregnancy, epilepsy, management and outcome: a 10-year perspective.
    Seizure, 1993, Volume: 2, Issue:4

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Birth Weight; Carbamazepine; Cohort Studies; Drug Ther

1993
Syndromal and nonsyndromal primary trigonocephaly: analysis of a series of 237 patients.
    American journal of medical genetics, 1998, Jan-13, Volume: 75, Issue:2

    Topics: Birth Weight; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Craniosynostose

1998
Antiepileptics and the development of congenital anomalies.
    Neurology, 1992, Volume: 42, Issue:4 Suppl 5

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Apgar Score; Birth Weight; Carbamazepine; Epilepsy; Fe

1992
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].
    Rinsho shinkeigaku = Clinical neurology, 1991, Volume: 31, Issue:3

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Carbamazepine; Embryonic and Feta

1991
Induction of postaxial forelimb ectrodactyly with anticonvulsant agents in A/J mice.
    Teratology, 1990, Volume: 41, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Dimethadione; Female; Fetal Death; Fetal Resorpt

1990