valproic acid has been researched along with Biotinidase Deficiency in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Biotinidase Deficiency: The late onset form of MULTIPLE CARBOXYLASE DEFICIENCY (deficiency of the activities of biotin-dependent enzymes propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, and PYRUVATE CARBOXYLASE) due to a defect or deficiency in biotinidase which is essential for recycling BIOTIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid (VPA) is a widely used and well-tolerable antiepileptic drug in epileptic patients." | 5.35 | The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid. ( Akin, R; Arslan, M; Balamtekin, N; Kurt, I; Ozcan, O; Unay, B; Vurucu, S, 2009) |
| "Valproic acid (VPA) is a widely used and well-tolerable antiepileptic drug in epileptic patients." | 1.35 | The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid. ( Akin, R; Arslan, M; Balamtekin, N; Kurt, I; Ozcan, O; Unay, B; Vurucu, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arslan, M | 1 |
| Vurucu, S | 1 |
| Balamtekin, N | 1 |
| Unay, B | 1 |
| Akin, R | 1 |
| Kurt, I | 1 |
| Ozcan, O | 1 |
1 other study available for valproic acid and Biotinidase Deficiency
| Article | Year |
|---|---|
The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid.
Topics: Alopecia; Animals; Anticonvulsants; Avitaminosis; Biotin; Biotinidase; Biotinidase Deficiency; Dieta | 2009 |