valproic acid has been researched along with Biological Clock Disturbances in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using rats exposed prenatally to valproic acid (VPA) as an animal model of autism, we examined locomotor activity and feeding under a reversed 12-h light/dark cycle, and found disturbance of the circadian rhythm characterized by frequent arousal during the light/sleep phase." | 3.74 | Abnormality of circadian rhythm accompanied by an increase in frontal cortex serotonin in animal model of autism. ( Arita, H; Nakamura, M; Nakasato, A; Nakatani, Y; Seki, Y; Sugawara, M; Tsujino, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsujino, N | 1 |
| Nakatani, Y | 1 |
| Seki, Y | 1 |
| Nakasato, A | 1 |
| Nakamura, M | 1 |
| Sugawara, M | 1 |
| Arita, H | 1 |
1 other study available for valproic acid and Biological Clock Disturbances
| Article | Year |
|---|---|
Abnormality of circadian rhythm accompanied by an increase in frontal cortex serotonin in animal model of autism.
Topics: Animals; Animals, Newborn; Autistic Disorder; Behavior, Animal; Chronobiology Disorders; Disease Mod | 2007 |