valproic acid has been researched along with Benign Frontal Childhood Epilepsy in 11 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We review the various forms of partial epilepsy that appear in childhood and adolescence, emphasizing the most common forms." | 2.39 | [The diagnosis and treatment of partial epilepsy in childhood and adolescence]. ( Martínez Bermejo, Z; Pascual-Castroviejo, I, 1996) |
| "We report five adult patients with frontal lobe epilepsy (FLE) who were treated with VPA and in whom a primary adverse effect was unstable gait and falls." | 1.46 | Gait instability in valproate-treated patients: Call to measure ammonia levels. ( Elger, CE; Kipervasser, S; Korczyn, AD; Nass, RD; Neufeld, MY; Quesada, CM, 2017) |
| "Nocturnal frontal lobe epilepsy (NFLE) is an idiopathic partial epilepsy with a family history in about 25% of cases, with autosomal dominant inheritance (autosomal dominant NFLE [ADNFLE])." | 1.46 | Rationale for an adjunctive therapy with fenofibrate in pharmacoresistant nocturnal frontal lobe epilepsy. ( Aroni, S; Marrosu, F; Melis, M; Milioli, G; Muntoni, AL; Parrino, L; Pillolla, G; Pistis, M; Puligheddu, M; Sagheddu, C; Terzano, GM, 2017) |
| "Methylphenidate is a short-acting stimulant." | 1.39 | Methylphenidate-induced acute orofacial and extremity dyskinesia. ( Donmez, A; Isik, B; Orun, E; Sonmez, FM; Tas, T; Yilmaz, AE, 2013) |
| "Treatment with levetiracetam produced a striking remission of seizures." | 1.34 | Coexistence of epileptic nocturnal wanderings and an arachnoid cyst. ( Avila-Ordoñez, MU; Díaz-Galviz, JL; García-Reyna, JC; Jiménez-Genchi, A, 2007) |
| "Idiopathic generalized epilepsy presenting with hemiconvulsive seizures has not, to our knowledge, been previously described." | 1.31 | Idiopathic generalized epilepsy presenting with hemiconvulsive seizures. ( Kiley, MA; Sander, JW; Smith, SJ, 2000) |
| " Dose-response inhibition curves determined on the control receptor and on ADNFLE-mutant receptors showed a greater sensitivity of the mutants to CBZ, with median inhibitory concentrations (IC50s) in the range of the antiepileptic plasma levels of CBZ." | 1.30 | Mutated nicotinic receptors responsible for autosomal dominant nocturnal frontal lobe epilepsy are more sensitive to carbamazepine. ( Bertrand, D; Bertrand, S; Picard, F; Steinlein, OK, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kipervasser, S | 1 |
| Elger, CE | 1 |
| Korczyn, AD | 1 |
| Nass, RD | 1 |
| Quesada, CM | 1 |
| Neufeld, MY | 1 |
| Puligheddu, M | 1 |
| Melis, M | 1 |
| Pillolla, G | 1 |
| Milioli, G | 1 |
| Parrino, L | 1 |
| Terzano, GM | 1 |
| Aroni, S | 1 |
| Sagheddu, C | 1 |
| Marrosu, F | 1 |
| Pistis, M | 1 |
| Muntoni, AL | 1 |
| Eastman, CL | 1 |
| Verley, DR | 1 |
| Fender, JS | 1 |
| Temkin, NR | 1 |
| D'Ambrosio, R | 1 |
| Boldyreva, SR | 1 |
| Ermakov, AIu | 1 |
| Yilmaz, AE | 1 |
| Donmez, A | 1 |
| Orun, E | 1 |
| Tas, T | 1 |
| Isik, B | 1 |
| Sonmez, FM | 1 |
| Jiménez-Genchi, A | 1 |
| Díaz-Galviz, JL | 1 |
| García-Reyna, JC | 1 |
| Avila-Ordoñez, MU | 1 |
| Martínez Bermejo, Z | 1 |
| Pascual-Castroviejo, I | 1 |
| Picard, F | 1 |
| Bertrand, S | 1 |
| Steinlein, OK | 1 |
| Bertrand, D | 1 |
| Matheja, P | 1 |
| Weckesser, M | 1 |
| Debus, O | 1 |
| Löttgen, J | 1 |
| Schuierer, G | 1 |
| Schober, O | 1 |
| Kurlemann, G | 1 |
| Kiley, MA | 1 |
| Smith, SJ | 1 |
| Sander, JW | 1 |
| McCabe, PH | 1 |
| McNew, CD | 1 |
| Michel, NC | 1 |
1 review available for valproic acid and Benign Frontal Childhood Epilepsy
| Article | Year |
|---|---|
[The diagnosis and treatment of partial epilepsy in childhood and adolescence].
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epile | 1996 |
1 trial available for valproic acid and Benign Frontal Childhood Epilepsy
| Article | Year |
|---|---|
Effect of divalproex-lamotrigine combination therapy in frontal lobe seizures.
Topics: Adolescent; Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy, Frontal Lobe; Female; Human | 2001 |
9 other studies available for valproic acid and Benign Frontal Childhood Epilepsy
| Article | Year |
|---|---|
Gait instability in valproate-treated patients: Call to measure ammonia levels.
Topics: Accidental Falls; Adult; Ammonia; Anticonvulsants; Disease Progression; Epilepsy, Frontal Lobe; Fema | 2017 |
Rationale for an adjunctive therapy with fenofibrate in pharmacoresistant nocturnal frontal lobe epilepsy.
Topics: Adult; Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Disease Models, Animal; D | 2017 |
ECoG studies of valproate, carbamazepine and halothane in frontal-lobe epilepsy induced by head injury in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Evaluation, Preclinical; Electrodes; Electrophysiology | 2010 |
[Comparative efficacy of carbamazepine, valproic acid and topiramate in symptomatic and cryptogenic frontal lobe epilepsy in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy, Frontal Lobe; Female; | 2010 |
Methylphenidate-induced acute orofacial and extremity dyskinesia.
Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; C | 2013 |
Coexistence of epileptic nocturnal wanderings and an arachnoid cyst.
Topics: Adolescent; Anticonvulsants; Arachnoid Cysts; Electroencephalography; Epilepsy, Frontal Lobe; Humans | 2007 |
Mutated nicotinic receptors responsible for autosomal dominant nocturnal frontal lobe epilepsy are more sensitive to carbamazepine.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy, Frontal Lobe; E | 1999 |
Drug-induced changes in cerebral glucose consumption in bifrontal epilepsy.
Topics: Anticonvulsants; Carbamazepine; Cerebral Cortex; Child, Preschool; Cysteine; Electroencephalography; | 2000 |
Idiopathic generalized epilepsy presenting with hemiconvulsive seizures.
Topics: Adolescent; Anticonvulsants; Child; Comorbidity; Electroencephalography; Epilepsy, Frontal Lobe; Epi | 2000 |