valproic acid has been researched along with BCECTS in 26 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gender, seizure onset age, psychiatric diseases, seizure characteristics (semiology, duration, and relationship to sleep), last EEG time, and spike lateralization in the first EEG did not have a statistically significant effect on the SWI change." | 1.91 | The fate of spikes in self-limited epilepsy with centrotemporal spikes: Are clinical and baseline EEG features effective? ( Günay, Ç; Hiz Kurul, S; Özsoy, Ö; Sarikaya Uzan, G; Yiş, U, 2023) |
| "The average dosage of LEV was 22." | 1.40 | Evaluation of levetiracetam and valproic acid as low-dose monotherapies for children with typical benign childhood epilepsy with centrotemporal spikes (BECTS). ( An, D; Chen, S; Deng, H; Ren, J; Xiao, F; Zhou, D, 2014) |
| "With a clear correlation of EEG record, benign rolandic epilepsy was diagnosed, so the therapy with valproate was introduced." | 1.37 | Dilemmas in diagnostics and therapy of rolandic epilepsy. ( Skrijelj, F; Sokić, D, 2011) |
| "Forty-four patients with rolandic epilepsy (32 boys, 12 girls), aged from 5 to 14 years, were examined in the prospective study during 5 years." | 1.37 | [Transitory cognitive dysfunction in rolandic epilepsy]. ( Buchneva, IA; Ermakov, AIu; Ermolenko, NA; Voronkova, KV, 2011) |
| " For those who were treated, they were easily controlled on a low dose of carbamazepine (median dosage of 12." | 1.32 | Benign childhood epilepsy with centrotemporal spikes: a study of 50 Chinese children. ( Chan, KY; Ma, CK, 2003) |
| "Seven patients had comorbid psychiatric disorders, whereas six patients had epilepsy (three rolandic, two generalized, and one indeterminate)." | 1.31 | Pediatric migraine prophylaxis with divalproex. ( Drake, ME; Greenberg, G; Pakalnis, A; Paolichi, J, 2001) |
| "Atypical features of rolandic epilepsy are not uncommon, although the long-term prognosis of this condition is not known." | 1.31 | Typical and atypical rolandic epilepsy in childhood: a follow-up study. ( Chiarelli, F; Cutarella, R; Giannuzzi, R; Latini, G; Morgese, G; Trotta, D; Verrotti, A, 2002) |
| "The treatment with valproic acid (VPA) and clonazepam (CZP), has been very effective." | 1.30 | [Atypical benign partial epilepsy of childhood. Clinical follow-up EEG study of 3 patients]. ( Bauzano-Poley, E; Delgado-Marqués, MP; Mora-Ramírez, MD; Rodríguez-Barrionuevo, AC; Tosina-García, E, 1998) |
| " Seizures became diurnal and frequent, not modified by carbamazepine (CBZ) or valproate (VPA) but responding to VPA and lamotrigine (LTG) with recommended dosage schedules for this combination." | 1.30 | Paradoxic reaction to lamotrigine in a child with benign focal epilepsy of childhood with centrotemporal spikes. ( Boyd, S; Catania, S; Cross, H; de Sousa, C, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Günay, Ç | 1 |
| Sarikaya Uzan, G | 1 |
| Özsoy, Ö | 1 |
| Hiz Kurul, S | 1 |
| Yiş, U | 1 |
| Vargas, R | 1 |
| Beltrán, L | 1 |
| Lizama, R | 1 |
| Valenzuela, GR | 1 |
| Caraballo, R | 1 |
| Kanemura, H | 1 |
| Sano, F | 1 |
| Ohyama, T | 1 |
| Aihara, M | 1 |
| Xiao, F | 1 |
| An, D | 1 |
| Deng, H | 1 |
| Chen, S | 1 |
| Ren, J | 1 |
| Zhou, D | 1 |
| Galer, S | 1 |
| Urbain, C | 1 |
| De Tiège, X | 1 |
| Emeriau, M | 1 |
| Leproult, R | 1 |
| Deliens, G | 1 |
| Nonclerq, A | 1 |
| Peigneux, P | 1 |
| Van Bogaert, P | 1 |
| Liu, MJ | 1 |
| Su, XJ | 1 |
| Md, XS | 1 |
| Wu, GF | 1 |
| Zhang, YQ | 1 |
| Gao, L | 1 |
| Wang, W | 1 |
| Liao, JX | 1 |
| Wang, H | 1 |
| Mai, JN | 1 |
| Gao, JY | 1 |
| Shu, XM | 1 |
| Huang, SP | 1 |
| Zhang, L | 1 |
| Zou, LP | 1 |
| Liukkonen, E | 1 |
| Kantola-Sorsa, E | 1 |
| Paetau, R | 1 |
| Gaily, E | 1 |
| Peltola, M | 1 |
| Granström, ML | 1 |
| Bourrous, M | 1 |
| Draiss, G | 1 |
| Amine, M | 1 |
| Assabane, A | 1 |
| Bouskraoui, M | 1 |
| Skrijelj, F | 1 |
| Sokić, D | 1 |
| Cherian, A | 1 |
| Baheti, NN | 1 |
| Menon, RN | 1 |
| Iyer, RS | 1 |
| Rathore, C | 1 |
| Radhakrishnan, A | 1 |
| Ermolenko, NA | 2 |
| Ermakov, AIu | 2 |
| Voronkova, KV | 2 |
| Buchneva, IA | 2 |
| Zakharova, EI | 1 |
| Sakakihara, Y | 1 |
| Ma, CK | 1 |
| Chan, KY | 1 |
| Berroya, AG | 1 |
| McIntyre, J | 1 |
| Webster, R | 1 |
| Lah, S | 1 |
| Sabaz, M | 1 |
| Lawson, J | 1 |
| Bleasel, AF | 1 |
| Bye, AM | 1 |
| Cerminara, C | 1 |
| Montanaro, ML | 1 |
| Curatolo, P | 1 |
| Seri, S | 1 |
| Rasmussen, NH | 1 |
| Hansen, LK | 1 |
| Oka, E | 1 |
| Murakami, N | 1 |
| Ogino, T | 1 |
| Kobayashi, K | 1 |
| Ohmori, I | 1 |
| Akiyama, T | 1 |
| Ito, M | 1 |
| Karlov, VA | 1 |
| Gnezditskiĭ, VV | 1 |
| Rodríguez-Barrionuevo, AC | 1 |
| Bauzano-Poley, E | 1 |
| Delgado-Marqués, MP | 1 |
| Mora-Ramírez, MD | 1 |
| Tosina-García, E | 1 |
| Gelisse, P | 1 |
| Genton, P | 1 |
| Raybaud, C | 1 |
| Thiry, A | 1 |
| Pincemaille, O | 1 |
| Catania, S | 1 |
| Cross, H | 1 |
| de Sousa, C | 1 |
| Boyd, S | 1 |
| Jung, M | 1 |
| Gabriel, KH | 1 |
| Stolle, D | 1 |
| Pakalnis, A | 1 |
| Greenberg, G | 1 |
| Drake, ME | 1 |
| Paolichi, J | 1 |
| Verrotti, A | 1 |
| Latini, G | 1 |
| Trotta, D | 1 |
| Giannuzzi, R | 1 |
| Cutarella, R | 1 |
| Morgese, G | 1 |
| Chiarelli, F | 1 |
| Hamano, S | 1 |
| Mochizuki, M | 1 |
| Morikawa, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigating the Effect of Closed-loop Auditory Stimulation on Sleep and Behavior in Patients With Epilepsy and Healthy Controls: a Developmental Study[NCT04716673] | 120 participants (Anticipated) | Interventional | 2020-07-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for valproic acid and BCECTS
| Article | Year |
|---|---|
[Bening epilepsy of childhood with centrotemporal spikes].
Topics: Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsy, R | 2002 |
[Benign partial epilepsy with centrotemporal spikes in children (Roland's epilepsy). Treatment and prognosis].
Topics: Anticonvulsants; Carbamazepine; Child; Child Development; Epilepsy, Rolandic; Evidence-Based Medicin | 2004 |
2 trials available for valproic acid and BCECTS
| Article | Year |
|---|---|
Clinical features of benign epilepsy of childhood with centrotemporal spikes in chinese children.
Topics: Adolescent; Age of Onset; Anticonvulsants; Brain; Carbamazepine; Child; Child, Preschool; China; Dru | 2017 |
[ESES-syndrome in child- and adolescent psychiatry].
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Developmen | 2000 |
22 other studies available for valproic acid and BCECTS
| Article | Year |
|---|---|
The fate of spikes in self-limited epilepsy with centrotemporal spikes: Are clinical and baseline EEG features effective?
Topics: Electroencephalography; Epilepsy, Rolandic; Humans; Levetiracetam; Retrospective Studies; Seizures; | 2023 |
Benign rolandic epilepsy and generalized paroxysms: A study of 13 patients.
Topics: Anticonvulsants; Brain; Child; Child, Preschool; Electroencephalography; Epilepsy, Rolandic; Female; | 2018 |
Efficacy of levetiracetam for reducing rolandic discharges in comparison with carbamazepine and valproate sodium in rolandic epilepsy.
Topics: Anticonvulsants; Brain Waves; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilep | 2018 |
Evaluation of levetiracetam and valproic acid as low-dose monotherapies for children with typical benign childhood epilepsy with centrotemporal spikes (BECTS).
Topics: Anticonvulsants; Brain Waves; Case-Control Studies; Child; Cohort Studies; Electroencephalography; E | 2014 |
Impaired sleep-related consolidation of declarative memories in idiopathic focal epilepsies of childhood.
Topics: Anticonvulsants; Child; Electroencephalography; Epilepsies, Partial; Epilepsy, Rolandic; Female; Hum | 2015 |
Long-term outcome of 32 children with encephalopathy with status epilepticus during sleep, or ESES syndrome.
Topics: Adolescent; Anticonvulsants; Child; Cognition Disorders; Drug Therapy, Combination; Electroencephalo | 2010 |
[Childhood epilepsy with centrotemporal spikes in Marrakech].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Elec | 2010 |
Dilemmas in diagnostics and therapy of rolandic epilepsy.
Topics: Anticonvulsants; Child; Electroencephalography; Epilepsy, Rolandic; Female; Humans; Valproic Acid | 2011 |
Atonic variant of benign childhood epilepsy with centrotemporal spikes (atonic-BECTS): a distinct electro-clinical syndrome.
Topics: Age of Onset; Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy, Generalized; Epil | 2012 |
[Transitory cognitive dysfunction in rolandic epilepsy].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cognition Disorders; Drug Therapy, Combination | 2011 |
[Idiopathic focal epilepsies of infancy and childhood].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; El | 2011 |
Benign childhood epilepsy with centrotemporal spikes: a study of 50 Chinese children.
Topics: Adolescent; Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; China; Electroenc | 2003 |
Speech and language deterioration in benign rolandic epilepsy.
Topics: Anomia; Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Child, Preschool; Cognition Disorder | 2004 |
Lamotrigine-induced seizure aggravation and negative myoclonus in idiopathic rolandic epilepsy.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Electromyography; Epileps | 2004 |
Initiation of treatment and selection of antiepileptic drugs in childhood epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; | 2004 |
[Bifocal atypical rolandic epilepsy with speech dyspraxia].
Topics: Anti-Inflammatory Agents; Anticonvulsants; Apraxias; Child; Diagnosis, Differential; Electroencephal | 2004 |
[Atypical benign partial epilepsy of childhood. Clinical follow-up EEG study of 3 patients].
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Electroencephalography; Epilepsies, Pa | 1998 |
Benign childhood epilepsy with centrotemporal spikes and hippocampal atrophy.
Topics: Atrophy; Cerebral Cortex; Child; Electroencephalography; Epilepsy, Rolandic; Hippocampus; Humans; Ma | 1999 |
Paradoxic reaction to lamotrigine in a child with benign focal epilepsy of childhood with centrotemporal spikes.
Topics: Acute Disease; Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsy, Absence; Epi | 1999 |
Pediatric migraine prophylaxis with divalproex.
Topics: Adolescent; Child; Epilepsy, Generalized; Epilepsy, Rolandic; Female; Humans; Male; Mental Disorders | 2001 |
Typical and atypical rolandic epilepsy in childhood: a follow-up study.
Topics: Anticonvulsants; Brain; Carbamazepine; Child; Epilepsy, Rolandic; Female; Follow-Up Studies; Humans; | 2002 |
Phenobarbital-induced atypical absence seizure in benign childhood epilepsy with centrotemporal spikes.
Topics: Anticonvulsants; Child; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Epilep | 2002 |