valproic acid has been researched along with Autosomal Chromosome Disorders in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following treatment with antiepileptic drugs (AEDs), the patient developed several rare complications: after beginning therapy with phenytoin, the patient developed pseudolymphoma; after monotherapy with carbamazepine (CBZ), the patient thereafter developed myoclonic jerks of upper and lower limbs upon awakening; after one year of treatment with valproate (VPA) the patient developed clinical and immuno-haematological signs of SLE." | 3.69 | Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p. ( Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G, 1996) |
| "Epilepsy was controlled with valproate at the age of 6 years." | 2.42 | A study of EEG and epilepsy profile in Wolf-Hirschhorn syndrome and considerations regarding its correlation with other chromosomal disorders. ( Fiore, LA; Freitas, A; Kim, CA; Valente, KD, 2003) |
| "From a series of 1,713 patients with craniosynostosis hospitalized between 1976 and 1996, 237 propositi with metopic synostosis were analyzed." | 1.30 | Syndromal and nonsyndromal primary trigonocephaly: analysis of a series of 237 patients. ( Lajeunie, E; Le Merrer, M; Marchac, D; Renier, D, 1998) |
| "Spina Bifida, Congenital Heart Defects, Clefts, Diaphragmatic Hernia and Trisomy 18 were more frequent than expected among babies with maternal epilepsy." | 1.27 | Maternal epilepsy and birth defects: a case-control study in the Italian Multicentric Registry of Birth Defects (IPIMC). ( Bertollini, R; Mastroiacovo, P; Segni, G, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valente, KD | 1 |
| Freitas, A | 1 |
| Fiore, LA | 1 |
| Kim, CA | 1 |
| Gigli, GL | 1 |
| Scalise, A | 1 |
| Silvestri, G | 1 |
| Diomedi, M | 1 |
| Placidi, F | 1 |
| Pomponi, MG | 1 |
| Masala, C | 1 |
| Lajeunie, E | 1 |
| Le Merrer, M | 1 |
| Marchac, D | 1 |
| Renier, D | 1 |
| Bertollini, R | 1 |
| Mastroiacovo, P | 1 |
| Segni, G | 1 |
1 review available for valproic acid and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
A study of EEG and epilepsy profile in Wolf-Hirschhorn syndrome and considerations regarding its correlation with other chromosomal disorders.
Topics: Angelman Syndrome; Anticonvulsants; Child; Chromosome Deletion; Chromosome Disorders; Chromosomes, H | 2003 |
3 other studies available for valproic acid and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromoso | 1996 |
Syndromal and nonsyndromal primary trigonocephaly: analysis of a series of 237 patients.
Topics: Birth Weight; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Craniosynostose | 1998 |
Maternal epilepsy and birth defects: a case-control study in the Italian Multicentric Registry of Birth Defects (IPIMC).
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Chromosome Aberrations; Chromosome Disorders; Chromoso | 1985 |