Page last updated: 2024-10-26

valproic acid and Autoimmune Disease

valproic acid has been researched along with Autoimmune Disease in 6 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Sydenham's chorea is a symptom of rheumatic fever and results from an autoimmune attack on the CNS."2.39Neuropsychiatric aspects of Sydenham's chorea: a comprehensive review. ( Moore, DP, 1996)
"Opsoclonus-myoclonus-ataxia syndrome (OMS) is a rare neurological disorder of probably autoimmune origin."1.35Opsoclonus-myoclonus-ataxia syndrome with autoantibodies to glutamic acid decarboxylase. ( Alexiou, E; Gekas, G; Markakis, I; Rombos, A; Xifaras, M, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dowdell, KC1
Pesnicak, L1
Hoffmann, V1
Steadman, K1
Remaley, AT1
Cohen, JI1
Straus, SE1
Rao, VK1
Markakis, I1
Alexiou, E1
Xifaras, M1
Gekas, G1
Rombos, A1
Marghescu, S1
Neukam, D1
Andrew, M1
Barr, RD1
Moore, DP1
Sandler, RM1
Emberson, C1
Roberts, GE1
Voak, D1
Darnborough, J1
Heeley, AF1

Reviews

2 reviews available for valproic acid and Autoimmune Disease

ArticleYear
Increased platelet destruction in infancy and childhood.
    Seminars in thrombosis and hemostasis, 1982, Volume: 8, Issue:3

    Topics: Adrenal Cortex Hormones; Anemia, Hemolytic; Animals; Autoimmune Diseases; Blood Platelets; Child; Ch

1982
Neuropsychiatric aspects of Sydenham's chorea: a comprehensive review.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:9

    Topics: Adult; Autoimmune Diseases; Chorea; Comorbidity; Haloperidol; Humans; Mental Disorders; Obsessive-Co

1996

Other Studies

4 other studies available for valproic acid and Autoimmune Disease

ArticleYear
Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr(-/-) murine model of autoimmune lymphoproliferative syndrome (ALPS).
    Experimental hematology, 2009, Volume: 37, Issue:4

    Topics: Animals; Apoptosis; Autoimmune Diseases; Cell Proliferation; Cells, Cultured; Disease Models, Animal

2009
Opsoclonus-myoclonus-ataxia syndrome with autoantibodies to glutamic acid decarboxylase.
    Clinical neurology and neurosurgery, 2008, Volume: 110, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Autoantibodies; Autoimmune Diseases; Female; Gait

2008
[Autoallergic drug exanthemas].
    Fortschritte der Medizin, 1980, May-22, Volume: 98, Issue:19

    Topics: Autoimmune Diseases; Child; Epilepsy; Female; Humans; Lupus Erythematosus, Systemic; Male; Pemphigus

1980
IgM platelet autoantibody due to sodium valproate.
    British medical journal, 1978, Dec-16, Volume: 2, Issue:6153

    Topics: Autoantibodies; Autoimmune Diseases; Blood Platelets; Child; Humans; Immunoglobulin M; Male; Thrombo

1978