valproic acid has been researched along with Autoimmune Diabetes in 17 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We accepted him as type 1 diabetes mellitus (DM type 1)." | 5.33 | Risperidone-associated transient diabetic ketoacidosis and diabetes mellitus type 1 in a patient treated with valproate and lithium. ( Alpaslan, T; Bulent, C; Cengiz, T; Mithat, B, 2005) |
| " A 16-year-old young-boy, diagnosed with autism, developed diabetes mellitus type 1 whilst he was on treatment with olanzapine (started 4 months before), clomipramine, valproic acid and lithium." | 3.85 | Second-generation antipsychotic and diabetes mellitus in children and adolescents. ( Nurchi, AM; Pinna, AP; Podda, F; Ripoli, C; Tronci, MG; Zanni, R, 2017) |
| "Valproic acid has been shown to upregulate estrogen receptors (ERs) in breast and prostate cancer tissues." | 1.48 | Magnesium valproate ameliorates type 1 diabetes and cardiomyopathy in diabetic rats through estrogen receptors. ( Bhadada, S; Dudhrejiya, A; Patel, B; Rabadiya, S; Vaishnav, D, 2018) |
| "We accepted him as type 1 diabetes mellitus (DM type 1)." | 1.33 | Risperidone-associated transient diabetic ketoacidosis and diabetes mellitus type 1 in a patient treated with valproate and lithium. ( Alpaslan, T; Bulent, C; Cengiz, T; Mithat, B, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rabadiya, S | 1 |
| Bhadada, S | 1 |
| Dudhrejiya, A | 1 |
| Vaishnav, D | 1 |
| Patel, B | 1 |
| Ripoli, C | 1 |
| Pinna, AP | 1 |
| Podda, F | 1 |
| Zanni, R | 1 |
| Tronci, MG | 1 |
| Nurchi, AM | 1 |
| Hesemann, J | 1 |
| Lauer, E | 1 |
| Ziska, S | 1 |
| Noonan, K | 1 |
| Nemeth, B | 1 |
| Scott-Schwoerer, J | 1 |
| McCarty, C | 1 |
| Rasmussen, K | 1 |
| Goldberg, JM | 1 |
| Sund, S | 1 |
| Eickhoff, J | 1 |
| Raggio, CL | 1 |
| Giampietro, PF | 1 |
| Khan, S | 1 |
| Jena, G | 1 |
| Noh, H | 1 |
| Oh, EY | 1 |
| Seo, JY | 1 |
| Yu, MR | 1 |
| Kim, YO | 1 |
| Ha, H | 1 |
| Lee, HB | 1 |
| Young, L | 1 |
| Coffey, BJ | 1 |
| Sakai, K | 2 |
| Tavakoli, SA | 1 |
| Arguisola, MS | 1 |
| Mithat, B | 1 |
| Alpaslan, T | 1 |
| Bulent, C | 1 |
| Cengiz, T | 1 |
| Averbuch-Heller, L | 1 |
| Ben-Hur, T | 1 |
| Reches, A | 1 |
| Doucet, J | 1 |
| Fresel, J | 1 |
| Hue, G | 1 |
| Moore, N | 1 |
| Finnerty, M | 1 |
| Levin, Z | 1 |
| Miller, LJ | 1 |
| Schmid, RD | 1 |
| Coiro, V | 1 |
| Capretti, L | 1 |
| Bianconi, L | 1 |
| Castelli, A | 1 |
| Cerri, L | 1 |
| Roberti, G | 1 |
| Marcato, A | 1 |
| Volpi, R | 1 |
| Chiodera, P | 1 |
| Gatti, G | 1 |
| Crema, F | 1 |
| Attardo-Parrinello, G | 1 |
| Fratino, P | 1 |
| Aguzzi, F | 1 |
| Perucca, E | 1 |
| Turnbull, DM | 1 |
| Bone, AJ | 1 |
| Tames, FJ | 1 |
| Wilson, L | 1 |
| Baird, JD | 1 |
| Sherratt, HS | 1 |
2 reviews available for valproic acid and Autoimmune Diabetes
| Article | Year |
|---|---|
[Stiff-person syndrome].
Topics: Animals; Autoantibodies; Autoimmunity; Diabetes Mellitus, Type 1; Diagnosis, Differential; Diazepam; | 2002 |
[Stiff-man syndrome].
Topics: Autoantibodies; Diabetes Mellitus, Type 1; Diagnosis, Differential; Diazepam; GABA Agents; gamma-Ami | 2000 |
1 trial available for valproic acid and Autoimmune Diabetes
| Article | Year |
|---|---|
Reduction of baclofen-, but not sodium valproate-induced growth hormone release in type I diabetic men.
Topics: Adult; Baclofen; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; R | 1991 |
14 other studies available for valproic acid and Autoimmune Diabetes
| Article | Year |
|---|---|
Magnesium valproate ameliorates type 1 diabetes and cardiomyopathy in diabetic rats through estrogen receptors.
Topics: Animals; Cardiomegaly; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomy | 2018 |
Second-generation antipsychotic and diabetes mellitus in children and adolescents.
Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Benzodiazepines; Blood Glucose; Clomipramine; D | 2017 |
Analysis of maternal risk factors associated with congenital vertebral malformations.
Topics: Abnormalities, Multiple; Adolescent; Adult; Alcohol Drinking; Child; Clomiphene; Diabetes Mellitus, | 2013 |
Valproic Acid Improves Glucose Homeostasis by Increasing Beta-Cell Proliferation, Function, and Reducing its Apoptosis through HDAC Inhibition in Juvenile Diabetic Rat.
Topics: Animals; Apoptosis; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mel | 2016 |
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury.
Topics: Acetylcysteine; Amides; Animals; Antioxidants; Biphenyl Compounds; Cell Line; Cell Transdifferentiat | 2009 |
Bipolar disorder and valproate-induced hyperammonemic encephalopathy in an adolescent with diabetes.
Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Diabetes Mellitus, Type 1; Humans; Hyperammonemia; M | 2010 |
Diabetic ketoacidosis in a patient treated with olanzapine, valproic acid, and venlafaxine.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepi | 2003 |
Risperidone-associated transient diabetic ketoacidosis and diabetes mellitus type 1 in a patient treated with valproate and lithium.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ke | 2005 |
Valproate encephalopathy and hypocarnitinaemia in diabetic patients.
Topics: Adolescent; Adult; Brain Diseases; Carnitine; Diabetes Mellitus, Type 1; Electroencephalography; Epi | 1994 |
Protein binding of digitoxin, valproate and phenytoin in sera from diabetics.
Topics: Adult; Blood Proteins; Diabetes Mellitus, Type 1; Digitoxin; Female; Humans; Male; Phenytoin; Protei | 1993 |
Acute manic episodes in pregnancy.
Topics: Adult; Bipolar Disorder; Chlorpromazine; Comorbidity; Diabetes Mellitus, Type 1; Drug Therapy, Combi | 1996 |
Propionic acid and dipropylacetic acid in the urine of patients treated with dipropylacetic acid.
Topics: Adolescent; Child; Child, Preschool; Chromatography, Gas; Diabetes Mellitus, Type 1; Female; Humans; | 1977 |
Serum protein binding of phenytoin and valproic acid in insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Blood Proteins; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Gl | 1987 |
The effect of valproate on blood metabolite concentrations in spontaneously diabetic, ketoacidotic, BB/E Wistar rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Drug Evaluation, Preclinic | 1985 |