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valproic acid and Atypical Cluster Headache

valproic acid has been researched along with Atypical Cluster Headache in 17 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Among headache types, unclassifiable chronic headache segregated from all other classified headaches in terms of poor response."2.71Treatment of primary headache disorders with intravenous valproate: initial outpatient experience. ( Rybicki, LA; Stillman, MJ; Zajac, D, 2004)
" This once-a-day dosing formulation may increase compliance."2.46Valproate semisodium ER for migraine and cluster headache prophylaxis. ( Lovell, BV; Marmura, MJ, 2010)
"All papers on cluster headaches were reviewed according to preset criteria under the following headings: classification, epidemiology, aetiology, pathophysiology, and clinical features."2.41Cluster headache: review of the literature. ( Zakrzewska, JM, 2001)
"Headaches are a common entity in the ambulatory population."2.40Diagnosis, prophylaxis, and treatment of headaches in the athlete. ( Kaplan, B; Swain, RA, 1997)
"A relation between head trauma and cluster headache is frequently described in the literature."2.38Cluster headache following head injury: a case report and review of the literature. ( Casaly, JS; Dawson, GA; Turkewitz, LJ; Wirth, O, 1992)
"The therapeutic procedures of cluster headache begin from the precise diagnose."1.39[Therapeuetic aspects of cluster headache in the practical clinical site]. ( Owada, K, 2013)
"Verapamil 360 mg/day was found to be superior to placebo in one clinical trial."1.38Management of cluster headache. ( Jensen, RH; Tfelt-Hansen, PC, 2012)
"Cluster headache is a rare primary headache disorder characterized by recurrent, stereotyped short-lasting attacks of severe, unilateral head pain accompanied by autonomic symptoms."1.37Cluster headache associated with a sixth nerve palsy: a case report. ( Grosberg, BM; Lipton, RB; Robbins, MS; Vollbracht, S, 2011)
"We present a patient with cluster headache who was refractory to multiple acute and preventive medications but successfully aborted his attacks with recreational marijuana use; subsequent use of dronabinol provided equally effective pain relief."1.35Cluster attacks responsive to recreational cannabis and dronabinol. ( Grosberg, BM; Robbins, MS; Solomon, S; Tarshish, S, 2009)
"Sixty-one percent of migraineurs and 73% of cluster patients noted a decrease in pain with divalproex sodium and continued that therapy for more than 3 months."1.31Divalproex sodium in the treatment of migraine and cluster headaches. ( Freitag, FG; Gallagher, RM; Mueller, LL, 2002)
"A 60-year-old woman with secondary chronic cluster headache had increased serum ferritin and serum transferrin saturation and was homozygous for the C282Y mutation in the HFE gene, which is indicative of hereditary haemochromatosis."1.31Hereditary haemochromatosis in two cousins with cluster headache. ( Bjerve, KS; Hagen, K; Stovner, LJ; Waage, A, 2002)
"Fifteen cluster headache patients were studied of whom two suffered from chronic cluster headache and thirteen from the episodic type."1.28Sodium valproate in the treatment of cluster headache: an open clinical trial. ( Hering, R; Kuritzky, A, 1989)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's2 (11.76)18.2507
2000's9 (52.94)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prakash, S1
Adroja, B1
Parekh, H1
Owada, K1
Robbins, MS2
Tarshish, S1
Solomon, S1
Grosberg, BM2
Lovell, BV1
Marmura, MJ1
Vollbracht, S1
Lipton, RB1
Tfelt-Hansen, PC1
Jensen, RH1
Stillman, MJ1
Zajac, D1
Rybicki, LA1
Pascual, J1
Láinez, MJ1
Dodick, D1
Hering-Hanit, R1
D'Amico, D1
Swain, RA1
Kaplan, B1
Zakrzewska, JM1
Lüttmann, RJ1
Frese, A1
Erfurth, A1
Husstedt, IW1
Evers, S1
Gallagher, RM1
Mueller, LL1
Freitag, FG1
El Amrani, M1
Massiou, H1
Bousser, MG1
Stovner, LJ1
Hagen, K1
Waage, A1
Bjerve, KS1
Turkewitz, LJ1
Wirth, O1
Dawson, GA1
Casaly, JS1
Hering, R1
Kuritzky, A1

Reviews

6 reviews available for valproic acid and Atypical Cluster Headache

ArticleYear
Valproate semisodium ER for migraine and cluster headache prophylaxis.
    Expert opinion on drug metabolism & toxicology, 2010, Volume: 6, Issue:4

    Topics: Cluster Headache; Humans; Migraine Disorders; Valproic Acid

2010
Antiepileptic drugs for the treatment of chronic and episodic cluster headache: a review.
    Headache, 2007, Volume: 47, Issue:1

    Topics: Amines; Anticonvulsants; Cluster Headache; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-

2007
Antiepileptic drugs in the prophylaxis of migraine, chronic headache forms and cluster headache: a review of their efficacy and tolerability.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2007, Volume: 28 Suppl 2

    Topics: Anticonvulsants; Clinical Trials as Topic; Cluster Headache; Drug Resistance; Fructose; Headache Dis

2007
Diagnosis, prophylaxis, and treatment of headaches in the athlete.
    Southern medical journal, 1997, Volume: 90, Issue:9

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic;

1997
Cluster headache: review of the literature.
    The British journal of oral & maxillofacial surgery, 2001, Volume: 39, Issue:2

    Topics: Anticonvulsants; Clinical Protocols; Cluster Headache; Diagnosis, Differential; Humans; Migraine Dis

2001
Cluster headache following head injury: a case report and review of the literature.
    Headache, 1992, Volume: 32, Issue:10

    Topics: Adult; Cluster Headache; Craniocerebral Trauma; Female; Humans; Valproic Acid

1992

Trials

2 trials available for valproic acid and Atypical Cluster Headache

ArticleYear
Treatment of primary headache disorders with intravenous valproate: initial outpatient experience.
    Headache, 2004, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Cluster Headache; Female; Headache Disorders; Humans; Infu

2004
A negative trial of sodium valproate in cluster headache: methodological issues.
    Cephalalgia : an international journal of headache, 2002, Volume: 22, Issue:3

    Topics: Adult; Chi-Square Distribution; Cluster Headache; Double-Blind Method; Female; Humans; Male; Middle

2002

Other Studies

9 other studies available for valproic acid and Atypical Cluster Headache

ArticleYear
Serotonin syndrome in patients with headache disorders.
    BMJ case reports, 2017, Aug-07, Volume: 2017

    Topics: Acetaminophen; Adult; Amitriptyline; Analgesics; Cluster Headache; Drug Therapy, Combination; Flunar

2017
[Therapeuetic aspects of cluster headache in the practical clinical site].
    Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11

    Topics: Adult; Amines; Amitriptyline; Cluster Headache; Cyclohexanecarboxylic Acids; Drug Therapy, Combinati

2013
Cluster attacks responsive to recreational cannabis and dronabinol.
    Headache, 2009, Volume: 49, Issue:6

    Topics: Analgesics, Non-Narcotic; Cannabis; Cluster Headache; Dihydroergotamine; Diphenhydramine; Dronabinol

2009
Cluster headache associated with a sixth nerve palsy: a case report.
    Cephalalgia : an international journal of headache, 2011, Volume: 31, Issue:1

    Topics: Abducens Nerve Diseases; Anti-Inflammatory Agents; Cluster Headache; Dexamethasone; GABA Agents; Hum

2011
Management of cluster headache.
    CNS drugs, 2012, Jul-01, Volume: 26, Issue:7

    Topics: Analgesics; Cluster Headache; Deep Brain Stimulation; Disease Management; Ergotamine; Fructose; Huma

2012
Corticosteroid-induced acute mania during a cluster headache episode.
    Cephalalgia : an international journal of headache, 2001, Volume: 21, Issue:8

    Topics: Acute Disease; Adolescent; Age of Onset; Antimanic Agents; Bipolar Disorder; Cluster Headache; Gluco

2001
Divalproex sodium in the treatment of migraine and cluster headaches.
    The Journal of the American Osteopathic Association, 2002, Volume: 102, Issue:2

    Topics: Cluster Headache; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up

2002
Hereditary haemochromatosis in two cousins with cluster headache.
    Cephalalgia : an international journal of headache, 2002, Volume: 22, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Stem; Calcium Channel Blockers; Cluster Headac

2002
Sodium valproate in the treatment of cluster headache: an open clinical trial.
    Cephalalgia : an international journal of headache, 1989, Volume: 9, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cluster Headache; Female; Humans; Male; Middle Aged; Pilot Projects;

1989