valproic acid has been researched along with Atrial Remodeling in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Atrial Remodeling: Long-term changes in the electrophysiological parameters and/or anatomical structures of the HEART ATRIA that result from prolonged changes in atrial rate, often associated with ATRIAL FIBRILLATION or long periods of intense EXERCISE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation." | 5.51 | HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice. ( Hamer, S; Hammer, E; Himmler, K; Müller, FU; Pluteanu, F; Scholz, B; Schulte, JS; Seidl, MD; Stein, J; Völker, U; Wardelmann, E, 2019) |
| "A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation." | 1.51 | HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice. ( Hamer, S; Hammer, E; Himmler, K; Müller, FU; Pluteanu, F; Scholz, B; Schulte, JS; Seidl, MD; Stein, J; Völker, U; Wardelmann, E, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scholz, B | 1 |
| Schulte, JS | 1 |
| Hamer, S | 1 |
| Himmler, K | 1 |
| Pluteanu, F | 1 |
| Seidl, MD | 1 |
| Stein, J | 1 |
| Wardelmann, E | 1 |
| Hammer, E | 1 |
| Völker, U | 1 |
| Müller, FU | 1 |
1 other study available for valproic acid and Atrial Remodeling
| Article | Year |
|---|---|
HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Remodeling; Cyclic A | 2019 |