valproic acid has been researched along with Atrial Fibrillation in 6 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation." | 5.51 | HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice. ( Hamer, S; Hammer, E; Himmler, K; Müller, FU; Pluteanu, F; Scholz, B; Schulte, JS; Seidl, MD; Stein, J; Völker, U; Wardelmann, E, 2019) |
| "Valproic acid (VPA) and warfarin are commonly prescribed for patients with epilepsy and concomitant atrial fibrillation (AF)." | 4.98 | The critical interaction between valproate sodium and warfarin: case report and review. ( Dong, C; Ren, L; Song, P; Sui, Y; Sun, X; Xu, B; Zhao, W; Zhou, C, 2018) |
| "This study revealed the higher risk of cardiac arrhythmias persists long term in people with epilepsy, especially among those using carbamazepine and valproic acid." | 4.31 | Epilepsy and long-term risk of arrhythmias. ( Cai, J; Feng, Z; Huang, P; Liu, P; Lu, J; Lu, Y; Tang, H; Wang, J; Yang, G; Yang, Y; Yu, Q; Yuan, H, 2023) |
| "A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation." | 1.51 | HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice. ( Hamer, S; Hammer, E; Himmler, K; Müller, FU; Pluteanu, F; Scholz, B; Schulte, JS; Seidl, MD; Stein, J; Völker, U; Wardelmann, E, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Huang, P | 1 |
| Yu, Q | 1 |
| Lu, J | 1 |
| Liu, P | 1 |
| Yang, Y | 1 |
| Feng, Z | 1 |
| Cai, J | 1 |
| Yang, G | 1 |
| Yuan, H | 1 |
| Tang, H | 1 |
| Lu, Y | 1 |
| Langenbruch, L | 1 |
| Meuth, SG | 1 |
| Wiendl, H | 1 |
| Mesters, R | 1 |
| Möddel, G | 1 |
| Zhou, C | 1 |
| Sui, Y | 1 |
| Zhao, W | 1 |
| Dong, C | 1 |
| Ren, L | 1 |
| Song, P | 1 |
| Xu, B | 1 |
| Sun, X | 1 |
| Scholz, B | 1 |
| Schulte, JS | 1 |
| Hamer, S | 1 |
| Himmler, K | 1 |
| Pluteanu, F | 1 |
| Seidl, MD | 1 |
| Stein, J | 1 |
| Wardelmann, E | 1 |
| Hammer, E | 1 |
| Völker, U | 1 |
| Müller, FU | 1 |
| Chabwine, JN | 1 |
| Rossetti, AR | 1 |
| Hirt, L | 1 |
| Kuntzer, T | 1 |
| Schluep, M | 1 |
| Michel, P | 1 |
| Démonet, JF | 1 |
| du Pasquier, RA | 1 |
| Vingerhoets, FG | 1 |
| Vedovello, M | 1 |
| Baldacci, F | 1 |
| Nuti, A | 1 |
| Cipriani, G | 1 |
| Ulivi, M | 1 |
| Vergallo, A | 1 |
| Borelli, P | 1 |
1 review available for valproic acid and Atrial Fibrillation
| Article | Year |
|---|---|
The critical interaction between valproate sodium and warfarin: case report and review.
Topics: Aged; Anticoagulants; Anticonvulsants; Atrial Fibrillation; Drug Interactions; Female; Humans; Inter | 2018 |
5 other studies available for valproic acid and Atrial Fibrillation
| Article | Year |
|---|---|
Epilepsy and long-term risk of arrhythmias.
Topics: Atrial Fibrillation; Carbamazepine; Epilepsy; Genetic Predisposition to Disease; Humans; Valproic Ac | 2023 |
Clinically relevant interaction of rivaroxaban and valproic acid - A case report.
Topics: Administration, Oral; Adult; Anticoagulants; Anticonvulsants; Atrial Fibrillation; Factor Xa Inhibit | 2020 |
HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Remodeling; Cyclic A | 2019 |
[Neurology].
Topics: Antibodies, Monoclonal; Anticonvulsants; Atrial Fibrillation; Carbamates; Chronic Disease; Deep Brai | 2012 |
Peri-ictal prolonged atrial fibrillation after generalized seizures: description of a case and etiopathological considerations.
Topics: Anticonvulsants; Atrial Fibrillation; Electrocardiography; Electroencephalography; Follow-Up Studies | 2012 |