valproic acid has been researched along with Asphyxia in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Asphyxia: A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been reported that valproic acid (VPA) combined with therapeutic hypothermia can improve survival and neurologic outcomes in a rat asphyxial cardiac arrest model." | 8.02 | HSP70-mediated neuroprotection by combined treatment of valproic acid with hypothermia in a rat asphyxial cardiac arrest model. ( Choi, KH; Choi, S; Jeong, HH; Kim, K; Oh, JS; Oh, YM; Park, J, 2021) |
| "Valproic acid (VPA) has been reported to have survival and neuroprotective effects in a cardiac arrest rat model." | 5.42 | Effect of valproic acid combined with therapeutic hypothermia on neurologic outcome in asphyxial cardiac arrest model of rats. ( Hwang, JE; Jo, YH; Kim, K; Kim, MA; Lee, JH; Lee, MJ, 2015) |
| "Valproic acid (VPA) has been known to reduce neuronal injury, has anti-inflammatory and anti-apoptotic effects as a histone deacetylase (HDAC) inhibitor." | 5.39 | Effect of valproic acid on survival and neurologic outcomes in an asphyxial cardiac arrest model of rats. ( Jo, YH; Kang, C; Kim, J; Kim, K; Kim, MA; Lee, JH; Lee, MJ; Lee, SH; Park, CJ; Rhee, JE, 2013) |
| "It has been reported that valproic acid (VPA) combined with therapeutic hypothermia can improve survival and neurologic outcomes in a rat asphyxial cardiac arrest model." | 4.02 | HSP70-mediated neuroprotection by combined treatment of valproic acid with hypothermia in a rat asphyxial cardiac arrest model. ( Choi, KH; Choi, S; Jeong, HH; Kim, K; Oh, JS; Oh, YM; Park, J, 2021) |
| "Valproic acid (VPA) has been reported to have survival and neuroprotective effects in a cardiac arrest rat model." | 1.42 | Effect of valproic acid combined with therapeutic hypothermia on neurologic outcome in asphyxial cardiac arrest model of rats. ( Hwang, JE; Jo, YH; Kim, K; Kim, MA; Lee, JH; Lee, MJ, 2015) |
| "Valproic acid (VPA) has been known to reduce neuronal injury, has anti-inflammatory and anti-apoptotic effects as a histone deacetylase (HDAC) inhibitor." | 1.39 | Effect of valproic acid on survival and neurologic outcomes in an asphyxial cardiac arrest model of rats. ( Jo, YH; Kang, C; Kim, J; Kim, K; Kim, MA; Lee, JH; Lee, MJ; Lee, SH; Park, CJ; Rhee, JE, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Oh, JS | 1 |
| Park, J | 1 |
| Kim, K | 3 |
| Jeong, HH | 1 |
| Oh, YM | 1 |
| Choi, S | 1 |
| Choi, KH | 1 |
| Lee, JH | 2 |
| Jo, YH | 2 |
| Lee, SH | 1 |
| Kang, C | 1 |
| Kim, J | 1 |
| Park, CJ | 1 |
| Kim, MA | 2 |
| Lee, MJ | 2 |
| Rhee, JE | 1 |
| Hwang, JE | 1 |
3 other studies available for valproic acid and Asphyxia
| Article | Year |
|---|---|
HSP70-mediated neuroprotection by combined treatment of valproic acid with hypothermia in a rat asphyxial cardiac arrest model.
Topics: Acetylation; Animals; Asphyxia; Combined Modality Therapy; Disease Models, Animal; Heart Arrest; HSP | 2021 |
Effect of valproic acid on survival and neurologic outcomes in an asphyxial cardiac arrest model of rats.
Topics: Animals; Asphyxia; Brain Diseases; Disease Models, Animal; Enzyme Inhibitors; Heart Arrest; Male; Ra | 2013 |
Effect of valproic acid combined with therapeutic hypothermia on neurologic outcome in asphyxial cardiac arrest model of rats.
Topics: Animals; Asphyxia; Brain Diseases; Combined Modality Therapy; Disease Models, Animal; Enzyme Inhibit | 2015 |