Page last updated: 2024-10-26

valproic acid and Asperger Disease

valproic acid has been researched along with Asperger Disease in 4 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"This case report describes two children who developed hyperammonemia together with frank manic behavior during treatment with a combination of valproic acid and risperidone."7.74Case report: valproic Acid and risperidone treatment leading to development of hyperammonemia and mania. ( Caplan, R; Carlson, T; Reynolds, CA, 2007)
"This case report describes two children who developed hyperammonemia together with frank manic behavior during treatment with a combination of valproic acid and risperidone."3.74Case report: valproic Acid and risperidone treatment leading to development of hyperammonemia and mania. ( Caplan, R; Carlson, T; Reynolds, CA, 2007)
"Epilepsy was diagnosed in 37% (375/1014) of the study participants."1.36Correlation between EEG abnormalities and symptoms of autism spectrum disorder (ASD). ( Yasuhara, A, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yasuhara, A1
Carlson, T1
Reynolds, CA1
Caplan, R1
Duggal, HS1
Hollander, E1
Dolgoff-Kaspar, R1
Cartwright, C1
Rawitt, R1
Novotny, S1

Trials

1 trial available for valproic acid and Asperger Disease

ArticleYear
An open trial of divalproex sodium in autism spectrum disorders.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:7

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Antipsychotic Agents; Asperger Syndrome; Autistic D

2001

Other Studies

3 other studies available for valproic acid and Asperger Disease

ArticleYear
Correlation between EEG abnormalities and symptoms of autism spectrum disorder (ASD).
    Brain & development, 2010, Volume: 32, Issue:10

    Topics: Adolescent; Age of Onset; Aging; Anticonvulsants; Asperger Syndrome; Autistic Disorder; Brain Mappin

2010
Case report: valproic Acid and risperidone treatment leading to development of hyperammonemia and mania.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2007, Volume: 46, Issue:3

    Topics: Antipsychotic Agents; Asperger Syndrome; Attention Deficit Disorder with Hyperactivity; Bipolar Diso

2007
Mood stabilizers in Asperger's syndrome.
    The Australian and New Zealand journal of psychiatry, 2001, Volume: 35, Issue:3

    Topics: Adult; Antimanic Agents; Asperger Syndrome; Bipolar Disorder; Drug Therapy, Combination; Humans; Lit

2001