valproic acid has been researched along with Aqueductal Stenosis in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fetal exposure to valproic acid has recently been associated with an increased incidence of neural tube defects." | 3.67 | Prenatal detection of a neural tube defect after fetal exposure to valproic acid. ( Campbell, WA; Cassidy, SB; Ciarleglio, L; Nochimson, DJ; Vintzileos, AM; Weinbaum, PJ, 1986) |
| " In the present work the effects of developmentally toxic doses of 2-ethylhexanoic acid (EHXA), 2-ethylhexanol (EHXO), and valproic acid (VPA) on Zn metabolism were investigated in the pregnant rat." | 1.30 | Altered zinc metabolism contributes to the developmental toxicity of 2-ethylhexanoic acid, 2-ethylhexanol and valproic acid. ( Bui, LM; Commisso, JF; Faber, WD; Keen, CL; Taubeneck, MW; Uriu-Hare, JY, 1998) |
| "However, the hydrocephalus remained stable even when the shunt was removed due to infection." | 1.28 | [A case of Klippel-Trenaunay-Weber syndrome accompanied by congenital hydrocephalus and micropolygyria]. ( Araki, R; Koide, H; Miyaji, T; Shime, H; Shioda, K, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Suri, R | 1 |
| Socol, DK | 1 |
| Gitlin, M | 1 |
| Sheen, VL | 1 |
| Basel-Vanagaite, L | 1 |
| Goodman, JR | 1 |
| Scheffer, IE | 1 |
| Bodell, A | 1 |
| Ganesh, VS | 1 |
| Ravenscroft, R | 1 |
| Hill, RS | 1 |
| Cherry, TJ | 1 |
| Shugart, YY | 1 |
| Barkovich, J | 1 |
| Straussberg, R | 1 |
| Walsh, CA | 1 |
| Carrim, ZI | 1 |
| McKay, L | 1 |
| Sidiki, SS | 1 |
| Lavy, TE | 1 |
| Bui, LM | 1 |
| Taubeneck, MW | 1 |
| Commisso, JF | 1 |
| Uriu-Hare, JY | 1 |
| Faber, WD | 1 |
| Keen, CL | 1 |
| Trompetter-van Woerden, ML | 1 |
| van der Zwan, A | 1 |
| Shime, H | 1 |
| Araki, R | 1 |
| Koide, H | 1 |
| Miyaji, T | 1 |
| Shioda, K | 1 |
| Weinbaum, PJ | 1 |
| Cassidy, SB | 1 |
| Vintzileos, AM | 1 |
| Campbell, WA | 1 |
| Ciarleglio, L | 1 |
| Nochimson, DJ | 1 |
1 trial available for valproic acid and Aqueductal Stenosis
| Article | Year |
|---|---|
[Experiences with sodium 2-propyl valerate (Depakine) in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Clinica | 1977 |
6 other studies available for valproic acid and Aqueductal Stenosis
| Article | Year |
|---|---|
Standard of Care: Reasonable But Not Perfect.
Topics: Abnormalities, Drug-Induced; Adult; Arnold-Chiari Malformation; Female; Humans; Hydrocephalus; Infan | 2020 |
Etiological heterogeneity of familial periventricular heterotopia and hydrocephalus.
Topics: Adult; Anticonvulsants; Blotting, Western; Brain; Child; Child, Preschool; Choristoma; Contractile P | 2004 |
Early intervention for the ocular and neurodevelopmental sequelae of Fetal Valproate Syndrome.
Topics: Abnormalities, Drug-Induced; Amblyopia; Anticonvulsants; Autistic Disorder; Child, Preschool; Cranio | 2007 |
Altered zinc metabolism contributes to the developmental toxicity of 2-ethylhexanoic acid, 2-ethylhexanol and valproic acid.
Topics: Animals; Caproates; Crown-Rump Length; Encephalocele; Female; Hexanols; Hydrocephalus; Liver; Metall | 1998 |
[A case of Klippel-Trenaunay-Weber syndrome accompanied by congenital hydrocephalus and micropolygyria].
Topics: Brain; Electroencephalography; Epilepsy, Generalized; Humans; Hydrocephalus; Infant, Newborn; Klippe | 1992 |
Prenatal detection of a neural tube defect after fetal exposure to valproic acid.
Topics: Abortion, Therapeutic; Adolescent; Epilepsy; Female; Fetal Diseases; Humans; Hydrocephalus; Meningom | 1986 |