valproic acid has been researched along with Apnea, Sleep in 5 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Replacement of phenytoin by valproic acid resulted in a 100-lb weight gain, exacerbation of sleep apnea, and right heart failure." | 3.73 | Lethal obesity associated with sodium valproate in a brain-injured patient. ( Althoff, RR; Black, DN; Daye, K; Pelletier, CA, 2005) |
| " An association between weight gain, obstructive sleep apnea, and lithium treatment is also illustrated." | 3.68 | Four cases of obstructive sleep apnea associated with treatment-resistant mania. ( Alpert, JE; Frankenburg, FR; Hudson, JI; Keck, PE; Strakowski, SM; Teschke, GC; Tohen, M; Wilson, DR, 1991) |
| "Clonazepam was stopped." | 1.36 | Late-onset nocturnal intractable seizure during sleep: what is the origin? ( Liesiene, V; Miliauskas, S; Sakalauskas, R; Zemaitis, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Revol, B | 1 |
| Jullian-Desayes, I | 1 |
| Guichard, K | 1 |
| Micoulaud-Franchi, JA | 1 |
| Tamisier, R | 1 |
| Philip, P | 1 |
| Joyeux-Faure, M | 1 |
| Pépin, JL | 1 |
| Miliauskas, S | 1 |
| Liesiene, V | 1 |
| Zemaitis, M | 1 |
| Sakalauskas, R | 1 |
| Black, DN | 1 |
| Althoff, RR | 1 |
| Daye, K | 1 |
| Pelletier, CA | 1 |
| Semba, H | 1 |
| Sugawara, H | 1 |
| Otsuka, M | 1 |
| Ueki, A | 1 |
| Strakowski, SM | 1 |
| Hudson, JI | 1 |
| Keck, PE | 1 |
| Wilson, DR | 1 |
| Frankenburg, FR | 1 |
| Alpert, JE | 1 |
| Teschke, GC | 1 |
| Tohen, M | 1 |
5 other studies available for valproic acid and Apnea, Sleep
| Article | Year |
|---|---|
Valproic acid and sleep apnoea: A disproportionality signal from the WHO pharmacovigilance database.
Topics: Databases, Factual; Humans; Pharmacovigilance; Sleep Apnea Syndromes; Valproic Acid | 2020 |
Late-onset nocturnal intractable seizure during sleep: what is the origin?
Topics: Anticonvulsants; Clonazepam; Epilepsy; Follow-Up Studies; Humans; Male; Middle Aged; Polysomnography | 2010 |
Lethal obesity associated with sodium valproate in a brain-injured patient.
Topics: Adult; Anticonvulsants; Brain Injuries; Epilepsy; Fatal Outcome; Heart Failure; Humans; Male; Obesit | 2005 |
[Nocturnal epilepsy associated with sleep apnea syndrome].
Topics: Circadian Rhythm; Epilepsy; Humans; Intermittent Positive-Pressure Ventilation; Male; Middle Aged; P | 2007 |
Four cases of obstructive sleep apnea associated with treatment-resistant mania.
Topics: Adult; Bipolar Disorder; Clonazepam; Female; Follow-Up Studies; Hospitalization; Humans; Lithium; Mi | 1991 |