valproic acid has been researched along with Anti-Glomerular Basement Membrane Disease in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Anti-Glomerular Basement Membrane Disease: An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Goodpasture's syndrome is a rare autoimmune disorder characterized by rapidly progressive glomerulonephritis (RPGN) and alveolar hemorrhage in the presence of antiglomerular basement membrane (anti-GBM) antibodies." | 1.36 | [Goodpasture's syndrome with neurologic involvement and negative ANCA]. ( Cobo, M; Delgado, P; González-Posada, JM; Hernández, D; Marrero, D; Pérez-Suárez, G; Rodríguez, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pérez-Suárez, G | 1 |
| Marrero, D | 1 |
| Rodríguez, R | 1 |
| Delgado, P | 1 |
| Cobo, M | 1 |
| González-Posada, JM | 1 |
| Hernández, D | 1 |
1 other study available for valproic acid and Anti-Glomerular Basement Membrane Disease
| Article | Year |
|---|---|
[Goodpasture's syndrome with neurologic involvement and negative ANCA].
Topics: Acute Kidney Injury; Anti-Glomerular Basement Membrane Disease; Antibodies, Antineutrophil Cytoplasm | 2010 |