Page last updated: 2024-10-26

valproic acid and Anoxia, Brain

valproic acid has been researched along with Anoxia, Brain in 14 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Chronic post-hypoxic myoclonus is a condition in which the predominant clinical picture is myoclonus following hypoxic brain damage, usually due to cardiorespiratory arrest."1.62[Response to perampanel in a patient with chronic post-hypoxic myoclonus]. ( de Toledo, M; Muro-García, I; Pastor, J; Vega, L; Vieira, A, 2021)
"We studied an observational cohort of comatose subjects treated at a single academic medical center after cardiac arrest from September 2010 to January 2018."1.51Association of antiepileptic drugs with resolution of epileptiform activity after cardiac arrest. ( Baldwin, MA; Callaway, CW; Coppler, PJ; Elmer, J; Kvaløy, JT; Solanki, P, 2019)
"Post-anoxic myoclonus is a rare movement disorder manifested by diffuse action-triggered jerking movements that may result in significant disability."1.33Post-anoxic myoclonus: a case presentation and review of management in the rehabilitation setting. ( Polesin, A; Stern, M, 2006)
"Three times acute cardiopulmonary arrest appeared during status asthmaticus."1.33[Lance-Adams syndrome in patient with anoxic encephalopathy in the course of bronchial asthma]. ( Budrewicz, SP; Koszewicz, MA; Kowalczyk, EE; Podemski, R; Słotwiński, K, 2006)
"A patient presented myoclonus involving all parts of the body after laryngospasm."1.32[Favorable course of Lance-Adams postanoxic action myoclonus]. ( Benabdejlil, M; Benomar, A; Chkili, T; Errguig, L; Messouak, W; Regragui, W; Yahyaoui, M, 2003)
"The data suggest that this rat cardiac arrest model may be a valuable tool for investigating the pathophysiologic mechanisms of posthypoxic myoclonus and for developing new therapeutic strategies for treating the disorder."1.29Novel rat cardiac arrest model of posthypoxic myoclonus. ( Hussong, MJ; Matsumoto, RR; Schwartz, PH; Truong, DD; Wasterlain, CG, 1994)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's4 (28.57)18.2507
2000's3 (21.43)29.6817
2010's2 (14.29)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Marcellino, C1
Wijdicks, EF1
Muro-García, I1
Vieira, A1
Vega, L1
Pastor, J1
de Toledo, M1
Solanki, P1
Coppler, PJ1
Kvaløy, JT1
Baldwin, MA1
Callaway, CW1
Elmer, J1
Jin, G1
Liu, B1
You, Z1
Bambakidis, T1
Dekker, SE1
Maxwell, J1
Halaweish, I1
Linzel, D1
Alam, HB1
Errguig, L1
Benomar, A1
Messouak, W1
Regragui, W1
Benabdejlil, M1
Yahyaoui, M1
Chkili, T1
Polesin, A1
Stern, M1
Kowalczyk, EE1
Koszewicz, MA1
Budrewicz, SP1
Podemski, R1
Słotwiński, K1
Truong, DD1
Matsumoto, RR1
Schwartz, PH1
Hussong, MJ1
Wasterlain, CG1
Wicklein, EM1
Schwendemann, G1
Liron, L1
Chambost, M1
Depierre, P1
Peillon, D1
Combe, C1
Fahn, S2
Carroll, WM1
Walsh, PJ1
Longmire, AW1
Seger, DL1

Other Studies

14 other studies available for valproic acid and Anoxia, Brain

ArticleYear
Posthypoxic action myoclonus (the Lance-Adams syndrome).
    BMJ case reports, 2020, Apr-16, Volume: 13, Issue:4

    Topics: Heart Arrest; Humans; Hypoxia, Brain; Levetiracetam; Male; Middle Aged; Myoclonus; Syndrome; Valproi

2020
[Response to perampanel in a patient with chronic post-hypoxic myoclonus].
    Revista de neurologia, 2021, Aug-01, Volume: 73, Issue:3

    Topics: Anticonvulsants; Carcinoma, Papillary; Clonazepam; Drug Therapy, Combination; Electroencephalography

2021
Association of antiepileptic drugs with resolution of epileptiform activity after cardiac arrest.
    Resuscitation, 2019, Volume: 142

    Topics: Anticonvulsants; Cohort Studies; Coma; Combined Modality Therapy; Electroencephalography; Female; He

2019
Development of a novel neuroprotective strategy: combined treatment with hypothermia and valproic acid improves survival in hypoxic hippocampal cells.
    Surgery, 2014, Volume: 156, Issue:2

    Topics: Acetylation; Animals; beta Catenin; Cell Hypoxia; Cell Line; Cell Survival; Cobalt; Combined Modalit

2014
[Favorable course of Lance-Adams postanoxic action myoclonus].
    Revue neurologique, 2003, Volume: 159, Issue:1

    Topics: Anticonvulsants; Disease Progression; Electroencephalography; Electrophysiology; Humans; Hypoxia, Br

2003
Post-anoxic myoclonus: a case presentation and review of management in the rehabilitation setting.
    Brain injury, 2006, Volume: 20, Issue:2

    Topics: Anticonvulsants; Clonazepam; Diazepam; Female; Heart Arrest; Humans; Hypoxia, Brain; Isoxazoles; Lev

2006
[Lance-Adams syndrome in patient with anoxic encephalopathy in the course of bronchial asthma].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2006, Volume: 59, Issue:7-8

    Topics: Adult; Asthma; Cardiopulmonary Resuscitation; Diagnosis, Differential; Electroencephalography; Femal

2006
Novel rat cardiac arrest model of posthypoxic myoclonus.
    Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:2

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Anticonvulsants; Clonazepam; Disease Models, Ani

1994
Use of clonazepam and valproate in patients with Lance Adams syndrome.
    Journal of the Royal Society of Medicine, 1993, Volume: 86, Issue:10

    Topics: Adult; Clonazepam; Humans; Hypoxia, Brain; Male; Valproic Acid

1993
[Effectiveness of valproic acid for postanoxic action myoclonus (Lance-Adams syndrome)].
    Annales francaises d'anesthesie et de reanimation, 1998, Volume: 17, Issue:10

    Topics: Adult; Anticonvulsants; Benzodiazepines; Humans; Hypoxia, Brain; Male; Myoclonus; Syndrome; Valproic

1998
Posthypoxic action myoclonus: review of the literature and report of two new cases with response to valproate and estrogen.
    Advances in neurology, 1979, Volume: 26

    Topics: Adult; Brain Diseases; Estrogens, Conjugated (USP); Female; Humans; Hypoxia; Hypoxia, Brain; Male; M

1979
Post-anoxic action myoclonus: improvement with valproic acid.
    The New England journal of medicine, 1978, Aug-10, Volume: 299, Issue:6

    Topics: Anticonvulsants; Female; Humans; Hypoxia, Brain; Middle Aged; Myoclonus; Valerates; Valproic Acid

1978
Functional independence in post-anoxic myoclonus: contribution of L-5-HTP sodium valproate and clonazepam.
    British medical journal, 1978, Dec-09, Volume: 2, Issue:6152

    Topics: 5-Hydroxytryptophan; Adult; Benzodiazepinones; Clonazepam; Drug Therapy, Combination; Female; Humans

1978
Cerebral edema from valproate?
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:4

    Topics: Brain Edema; Humans; Hypoxia, Brain; Male; Valproic Acid

1992