valproic acid has been researched along with Anorexia Nervosa in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Anorexia Nervosa: An eating disorder that is characterized by the lack or loss of APPETITE, known as ANOREXIA. Other features include excess fear of becoming OVERWEIGHT; BODY IMAGE disturbance; significant WEIGHT LOSS; refusal to maintain minimal normal weight; and AMENORRHEA. This disorder occurs most frequently in adolescent females. (APA, Thesaurus of Psychological Index Terms, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of valproate in the treatment of Anorexia Nervosa (AN) in children and adolescents is currently not recommended by clinical guidelines, due to lack of evidence." | 1.72 | Inpatient treatment of anorexia nervosa with adjunctive valproate: a case series of 14 young and adolescent patients. ( Parmeggiani, A; Pruccoli, J, 2022) |
| "Eating disorders are commonly associated with depressive symptoms." | 1.35 | Treatment emergent mania responding to valproate in a Chinese female adolescent population with eating disorders: a case series. ( Lee, EL; Tor, PC, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Pruccoli, J | 1 |
| Parmeggiani, A | 1 |
| Tor, PC | 1 |
| Lee, EL | 1 |
| Tachibana, N | 1 |
| Sugita, Y | 1 |
| Teshima, Y | 1 |
| Hishikawa, Y | 1 |
3 other studies available for valproic acid and Anorexia Nervosa
| Article | Year |
|---|---|
Inpatient treatment of anorexia nervosa with adjunctive valproate: a case series of 14 young and adolescent patients.
Topics: Adolescent; Anorexia Nervosa; Child; Hospitalization; Humans; Inpatients; Olanzapine; Valproic Acid | 2022 |
Treatment emergent mania responding to valproate in a Chinese female adolescent population with eating disorders: a case series.
Topics: Adolescent; Anorexia Nervosa; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Bulimia Nervosa; | 2008 |
A case of anorexia nervosa associated with epileptic seizures showing favorable responses to sodium valproate and clonazepam.
Topics: Adolescent; Anorexia Nervosa; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epileps | 1989 |