valproic acid has been researched along with Anhedonia in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Herein, we describe two young men with epilepsy who experienced severe loss of libido and anhedonia after levetiracetam intake." | 7.78 | Levetiracetam-associated loss of libido and anhedonia. ( Bramanti, P; Calabrò, RS; Italiano, D; Militi, D, 2012) |
| "Corticosterone plasma level was increased in the CUMS compared to the non-stressed group (p < 0." | 5.56 | Valproic acid administration exerts protective effects against stress-related anhedonia in rats. ( Barati, M; Eslami, M; Goudarzi, M; Mehrabi, S; Nahavandi, A; Shahbazi, A, 2020) |
| "Valproic acid (VPA) treatment during pregnancy is a risk factor for developing autism spectrum disorder, cognitive deficits, and stress-related disorders in children." | 4.31 | Adolescent swimming exercise following maternal valproic acid treatment improves cognition and reduces stress-related symptoms in offspring mice: Role of sex and brain cytokines. ( Amouzad Mahdirejei, H; Barzegari, A; Esmaeili, MH; Hanani, M; Salari, AA, 2023) |
| " Herein, we describe two young men with epilepsy who experienced severe loss of libido and anhedonia after levetiracetam intake." | 3.78 | Levetiracetam-associated loss of libido and anhedonia. ( Bramanti, P; Calabrò, RS; Italiano, D; Militi, D, 2012) |
| "Corticosterone plasma level was increased in the CUMS compared to the non-stressed group (p < 0." | 1.56 | Valproic acid administration exerts protective effects against stress-related anhedonia in rats. ( Barati, M; Eslami, M; Goudarzi, M; Mehrabi, S; Nahavandi, A; Shahbazi, A, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Barzegari, A | 1 |
| Amouzad Mahdirejei, H | 1 |
| Hanani, M | 1 |
| Esmaeili, MH | 1 |
| Salari, AA | 1 |
| Goudarzi, M | 1 |
| Nahavandi, A | 1 |
| Mehrabi, S | 1 |
| Eslami, M | 1 |
| Shahbazi, A | 1 |
| Barati, M | 1 |
| Calabrò, RS | 1 |
| Italiano, D | 1 |
| Militi, D | 1 |
| Bramanti, P | 1 |
3 other studies available for valproic acid and Anhedonia
| Article | Year |
|---|---|
Adolescent swimming exercise following maternal valproic acid treatment improves cognition and reduces stress-related symptoms in offspring mice: Role of sex and brain cytokines.
Topics: Anhedonia; Animals; Autism Spectrum Disorder; Behavior, Animal; Brain; Cognition; Cytokines; Disease | 2023 |
Valproic acid administration exerts protective effects against stress-related anhedonia in rats.
Topics: Anhedonia; Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Histone De | 2020 |
Levetiracetam-associated loss of libido and anhedonia.
Topics: Adult; Anhedonia; Anticonvulsants; Brain; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, C | 2012 |