valproic acid has been researched along with Angiohemophilia in 6 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid is commonly used in the management of childhood epilepsy." | 3.71 | Coagulation abnormalities and acquired von Willebrand's disease type 1 in children receiving valproic acid. ( Kavakli, K; Serdaroglu, G; Tekgül, H; Tütüncüoglu, S, 2002) |
| "Fibrinogen was significantly reduced." | 2.73 | High incidence of vaproate-induced coagulation disorders in children receiving valproic acid: a prospective study. ( Dempfle, CE; Gerstner, T; Keller, A; Koenig, S; Longin, E; Teich, M, 2008) |
| "Valproic acid (VPA) is an antiepileptic drug (AED) commonly used for generalized and focal epilepsies." | 1.33 | Valproate-associated coagulopathies are frequent and variable in children. ( Bell, N; Brand, J; Dempfle, CE; Gerstner, T; König, S; Longin, E; Teich, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koenig, S | 1 |
| Gerstner, T | 2 |
| Keller, A | 1 |
| Teich, M | 2 |
| Longin, E | 2 |
| Dempfle, CE | 2 |
| Eberl, W | 1 |
| Budde, U | 1 |
| Bentele, K | 1 |
| Christen, HJ | 1 |
| Knapp, R | 1 |
| Mey, A | 1 |
| Schneppenheim, R | 1 |
| Bell, N | 1 |
| Brand, J | 1 |
| König, S | 1 |
| Gil-Fernández, JJ | 1 |
| Serdaroglu, G | 1 |
| Tütüncüoglu, S | 1 |
| Kavakli, K | 1 |
| Tekgül, H | 1 |
| Kreuz, W | 1 |
| Linde, R | 1 |
| Funk, M | 1 |
| Meyer-Schrod, R | 1 |
| Föll, E | 1 |
| Nowak-Göttl, U | 1 |
| Jacobi, G | 1 |
| Vigh, Z | 1 |
| Scharrer, I | 1 |
1 trial available for valproic acid and Angiohemophilia
| Article | Year |
|---|---|
High incidence of vaproate-induced coagulation disorders in children receiving valproic acid: a prospective study.
Topics: Anticonvulsants; Blood Platelets; Child; Child, Preschool; Factor XIII; Female; Fibrinogen; Humans; | 2008 |
5 other studies available for valproic acid and Angiohemophilia
| Article | Year |
|---|---|
Acquired von Willebrand syndrome as side effect of valproic acid therapy in children is rare.
Topics: Anticonvulsants; Child; Factor VIII; Humans; Seizures; Valproic Acid; von Willebrand Diseases; von W | 2009 |
Valproate-associated coagulopathies are frequent and variable in children.
Topics: Age Factors; Anticonvulsants; Blood Coagulation Tests; Child; Coagulation Protein Disorders; Epileps | 2006 |
Analysis of surgical blood loss and number of blood transfusions after temporal lobe resection performed in adults with epilepsy receiving valproate (VPA) in the immediate preoperative period.
Topics: Adolescent; Adult; Aged; Bleeding Time; Blood Loss, Surgical; Blood Transfusion; Epilepsy, Temporal | 1997 |
Coagulation abnormalities and acquired von Willebrand's disease type 1 in children receiving valproic acid.
Topics: Adolescent; Anticonvulsants; Antigens; Blood Coagulation Tests; Child; Child, Preschool; Dose-Respon | 2002 |
Induction of von Willebrand disease type I by valproic acid.
Topics: Adolescent; Child; Child, Preschool; Factor VIII; Female; Humans; Infant; Male; Valproic Acid; von W | 1990 |