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valproic acid and Anesthesia

valproic acid has been researched along with Anesthesia in 5 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"Seizures were repetitive and death occurred in 10."5.28Antiepileptic drugs delay the onset of seizures induced by aminophylline in conscious rats. ( David, J; Joseph, T; Kulkarni, C, 1992)
" This compound blocked bicuculline induced seizures, did not elevate seizure threshold following iv infusion of metrazole, and blocked influx of Ca2+ ions into cerebellar granule cells induced by K+ or veratridine."3.69Aroyl(aminoacyl)pyrroles, a new class of anticonvulsant agents. ( Almond, HR; Carmosin, RJ; Carson, JR; Pitis, PM; Stables, JP; Swinyard, EA; Vaught, JL; White, HS; Wolf, HH, 1997)
"Rett's syndrome is a neurodevelopmental disorder which is caused by a mutation on the x-chromosome; thus, it only affects the female sex."1.30[Rett's syndrome: pathophysiology and anesthesiological implications]. ( Häuser, FM; Lennartz, H; Lukasewitz, P; Wichert, A, 1999)
"Seizures were repetitive and death occurred in 10."1.28Antiepileptic drugs delay the onset of seizures induced by aminophylline in conscious rats. ( David, J; Joseph, T; Kulkarni, C, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carson, JR1
Carmosin, RJ1
Pitis, PM1
Vaught, JL1
Almond, HR1
Stables, JP1
Wolf, HH1
Swinyard, EA1
White, HS1
Bleck, TP1
Häuser, FM1
Lukasewitz, P1
Wichert, A1
Lennartz, H1
Kulkarni, C1
Joseph, T1
David, J1
Crespi, F1
Keane, PE1
Morre, M1

Reviews

1 review available for valproic acid and Anesthesia

ArticleYear
Therapy for status epilepticus.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:4

    Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Eth

1983

Other Studies

4 other studies available for valproic acid and Anesthesia

ArticleYear
Aroyl(aminoacyl)pyrroles, a new class of anticonvulsant agents.
    Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11

    Topics: Anesthesia; Animals; Anticonvulsants; Bicuculline; Calcium; Cerebellum; Electroshock; Mice; Models,

1997
[Rett's syndrome: pathophysiology and anesthesiological implications].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1999, Volume: 34, Issue:9

    Topics: Adult; Anesthesia; Anticonvulsants; Blood Coagulation Disorders; Epilepsy; Female; Humans; Kidney Ca

1999
Antiepileptic drugs delay the onset of seizures induced by aminophylline in conscious rats.
    Indian journal of physiology and pharmacology, 1992, Volume: 36, Issue:1

    Topics: Aminophylline; Anesthesia; Animals; Anticonvulsants; Carbamazepine; Consciousness; Diazepam; Electro

1992
Anaesthesia abolishes the effect of valproate on extracellular 5-HIAA, DOPAC and ascorbate as measured in rat striatum by differential pulse voltammetry.
    British journal of pharmacology, 1986, Volume: 87, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia; Animals; Ascorbic Acid; Corpus Striatum; Dopamine; Hydro

1986