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valproic acid and Anemia, Macrocytic

valproic acid has been researched along with Anemia, Macrocytic in 5 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Anemia, Macrocytic: Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).

Research Excerpts

ExcerptRelevanceReference
"He had been treated with valproate for seizures since the age of 2 years."1.29Haematological disturbances during long-term valproate therapy. ( Brichard, B; Cornu, G; Ninane, J; Scheiff, JM; Vermylen, C, 1994)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vasudev, K1
Keown, P1
Gibb, I1
McAllister-Williams, RH1
Tsivkin, R1
Saito, E1
Kafantaris, V1
Brichard, B1
Vermylen, C1
Scheiff, JM1
Ninane, J1
Cornu, G1
Ozkara, C1
Dreifuss, FE1
Apperson Hansen, C1
Fawcett, RG1

Other Studies

5 other studies available for valproic acid and Anemia, Macrocytic

ArticleYear
Hematological effects of valproate in psychiatric patients: what are the risk factors?
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Anemia, Macrocytic; Blood Cell Count; Cross-Sectional Studies; Female; Hema

2010
Macrocytosis associated with divalproex treatment.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:6

    Topics: Anemia, Macrocytic; Anticonvulsants; Bipolar Disorder; Child; Dose-Response Relationship, Drug; Eryt

2005
Haematological disturbances during long-term valproate therapy.
    European journal of pediatrics, 1994, Volume: 153, Issue:5

    Topics: Adolescent; Anemia, Macrocytic; Dermatitis, Atopic; Humans; Male; Seizures; Thrombocytopenia; Valpro

1994
Changes in red blood cells with valproate therapy.
    Acta neurologica Scandinavica, 1993, Volume: 88, Issue:3

    Topics: Anemia, Macrocytic; Blood Platelets; Epilepsy; Erythrocyte Indices; Erythrocyte Volume; Erythrocytes

1993
Dose-related thrombocytopenia and macrocytic anemia associated with valproate use in bipolar disorder.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:3

    Topics: Anemia, Macrocytic; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Middle Aged; Myelod

1997