valproic acid has been researched along with Anaplastic Ependymoma in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "HL-60 cells and whole blood samples from healthy volunteers were incubated with valproic acid (0-8 mM) for 0-24 hours, with additional blood samples collected from ependymoma patients receiving valproic acid on the SIOP Ependymoma II clinical trial." | 5.30 | A novel imaging flow cytometry method for the detection of histone H4 acetylation in myeloid cells. ( Hutton, C; Jamieson, D; Uitrakul, S; Veal, GJ, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uitrakul, S | 1 |
| Hutton, C | 1 |
| Veal, GJ | 1 |
| Jamieson, D | 1 |
1 trial available for valproic acid and Anaplastic Ependymoma
| Article | Year |
|---|---|
A novel imaging flow cytometry method for the detection of histone H4 acetylation in myeloid cells.
Topics: Acetylation; Analysis of Variance; Antineoplastic Agents; Child; Dose-Response Relationship, Drug; E | 2019 |