valproic acid has been researched along with Alcohol Withdrawal Associated Autonomic Hyperactivity in 12 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alcohol withdrawal delirium is associated with significant morbidity and mortality." | 1.42 | Alcohol withdrawal delirium manifested by manic symptoms in an elderly patient. ( Chan, HY; Lee, KI, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, HY | 1 |
| Lee, KI | 1 |
| Bourgeois, JA | 1 |
| Koike, AK | 1 |
| Simmons, JE | 1 |
| Telles, S | 1 |
| Eggleston, C | 1 |
| Lum, E | 1 |
| Gorman, SK | 1 |
| Slavik, RS | 1 |
| Sillanpää, ML | 1 |
| Tress, W | 1 |
| Boeckh, E | 1 |
| Emrich, HM | 1 |
| von Zerssen, D | 1 |
| Kissling, W | 1 |
| Möller, HJ | 1 |
| Windorfer, A | 1 |
| Diehl, LW | 1 |
| Rosenthal, RN | 1 |
| Perkel, C | 1 |
| Singh, P | 1 |
| Anand, O | 1 |
| Miner, CR | 1 |
| Myrick, H | 1 |
| Brady, KT | 1 |
| Malcolm, R | 1 |
| Longo, LP | 1 |
| Campbell, T | 1 |
| Hubatch, S | 1 |
| Crabbe, JC | 1 |
| Young, ER | 1 |
| Tam, B | 1 |
| Kosobud, A | 1 |
| Belknap, JK | 1 |
| Laursen, SE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Assessment of Valproate on Ethanol Withdrawal[NCT03235531] | Phase 4 | 210 participants (Anticipated) | Interventional | 2017-07-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for valproic acid and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Valproic acid management of acute alcohol withdrawal.
Topics: Alcohol Withdrawal Delirium; Anticonvulsants; Benzodiazepines; Humans; Randomized Controlled Trials | 2006 |
4 trials available for valproic acid and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Effect of sodium valproate on mania. The GABA-hypothesis of affective disorders.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Alcohol Withdrawal Delirium; Bipolar Disorder; Cl | 1980 |
A pilot open randomized trial of valproate and phenobarbital in the treatment of acute alcohol withdrawal.
Topics: Adult; Affect; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Dose-Response Relationship, | 1998 |
Divalproex in the treatment of alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Anticonvulsants; Female; Humans; Lorazepam; | 2000 |
Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; Anticonvulsant | 2002 |
7 other studies available for valproic acid and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Alcohol withdrawal delirium manifested by manic symptoms in an elderly patient.
Topics: Alcohol Withdrawal Delirium; Alcoholic Intoxication; Bipolar Disorder; Drug Therapy, Combination; He | 2015 |
Adjunctive valproic acid for delirium and/or agitation on a consultation-liaison service: a report of six cases.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Delirium; Fever; Humans; Injections, Intra | 2005 |
Alcoholism: treatment of alcohol withdrawal symptoms.
Topics: Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Barbiturate | 1982 |
[Alcoholic withdrawal syndrome. Pathophysiological progress and therapeutic consequences].
Topics: Alcohol Withdrawal Delirium; Humans; Psychoses, Alcoholic; Valproic Acid | 1980 |
[The alcohol withdrawal syndrome and its therapy].
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Humans; Middle Aged; Patient Compliance; Psychomotor | 1980 |
[Complications of valproic acid therapy: an overview (author's transl)].
Topics: Adult; Alcohol Withdrawal Delirium; Chemical and Drug Induced Liver Injury; Child; Coma; Electroence | 1981 |
Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity.
Topics: Alcohol Withdrawal Delirium; Alcohols; Animals; Anticonvulsants; Diazepam; Disease Susceptibility; E | 1986 |