Page last updated: 2024-10-26

valproic acid and Albuminuria

valproic acid has been researched along with Albuminuria in 2 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"To quantify absolute and relative risks of chronic kidney disease (CKD) progression and acute kidney injury (AKI) in people who initiated lithium compared with valproate therapy and to investigate the association between cumulative use and elevated lithium levels and kidney outcomes."4.31Absolute and Relative Risks of Kidney Outcomes Associated With Lithium vs Valproate Use in Sweden. ( Bellocco, R; Bosi, A; Carrero, JJ; Ceriani, L; Chang, Z; Clase, CM; Elinder, CG; Fu, EL; Landén, M; Runesson, B; Sjölander, A, 2023)
" Intriguingly, this reduction of GM3 and nephrin, as well as albuminuria, were inhibited by administration of valproic acid."4.12Glycosphingolipid GM3 prevents albuminuria and podocytopathy induced by anti-nephrin antibody. ( Furukawa, JI; Hanamatsu, H; Iwasaki, N; Kawashima, N; Nagane, M; Naito, S; Nakayama, KI; Takeuchi, Y; Yamashita, T, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Kawashima, N1
Naito, S1
Hanamatsu, H1
Nagane, M1
Takeuchi, Y1
Furukawa, JI1
Iwasaki, N1
Yamashita, T1
Nakayama, KI1
Bosi, A1
Clase, CM1
Ceriani, L1
Sjölander, A1
Fu, EL1
Runesson, B1
Chang, Z1
Landén, M1
Bellocco, R1
Elinder, CG1
Carrero, JJ1

Other Studies

2 other studies available for valproic acid and Albuminuria

ArticleYear
Glycosphingolipid GM3 prevents albuminuria and podocytopathy induced by anti-nephrin antibody.
    Scientific reports, 2022, 09-26, Volume: 12, Issue:1

    Topics: Albuminuria; Animals; Glycosphingolipids; Mice; Podocytes; Proteinuria; Valproic Acid

2022
Absolute and Relative Risks of Kidney Outcomes Associated With Lithium vs Valproate Use in Sweden.
    JAMA network open, 2023, Jul-03, Volume: 6, Issue:7

    Topics: Acute Kidney Injury; Adult; Albuminuria; Cohort Studies; Creatinine; Female; Humans; Kidney; Lithium

2023