valproic acid has been researched along with Airflow Obstruction, Chronic in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Valproic acid (VPA) is an inhibitor of PE and could possibly have an effect on the severity of chronic inflammation." | 7.80 | Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation. ( Abdul Roda, M; Blalock, JE; Braber, S; Folkerts, G; Gaggar, A; Hardison, MT; Jablonsky, MJ; Jackson, PL; Redegeld, FA; Sadik, M, 2014) |
| " Valproic acid (VPA) is an inhibitor of PE and could possibly have an effect on the severity of chronic inflammation." | 3.80 | Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation. ( Abdul Roda, M; Blalock, JE; Braber, S; Folkerts, G; Gaggar, A; Hardison, MT; Jablonsky, MJ; Jackson, PL; Redegeld, FA; Sadik, M, 2014) |
| "Valproic acid is an anticonvulsant that also inhibits histone deacetylase (HDAC), a property that could worsen pulmonary function in patients with chronic obstructive pulmonary disease (COPD)." | 1.42 | Safety of valproic acid in patients with chronic obstructive pulmonary disease: a population-based cohort study. ( Antoniou, T; Camacho, X; Gomes, T; Juurlink, DN; Mamdani, MM; Yao, Z, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdul Roda, M | 1 |
| Sadik, M | 1 |
| Gaggar, A | 1 |
| Hardison, MT | 1 |
| Jablonsky, MJ | 1 |
| Braber, S | 1 |
| Blalock, JE | 1 |
| Redegeld, FA | 1 |
| Folkerts, G | 1 |
| Jackson, PL | 1 |
| Antoniou, T | 1 |
| Yao, Z | 1 |
| Camacho, X | 1 |
| Mamdani, MM | 1 |
| Juurlink, DN | 1 |
| Gomes, T | 1 |
| Lin, AY | 1 |
3 other studies available for valproic acid and Airflow Obstruction, Chronic
| Article | Year |
|---|---|
Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation.
Topics: Animals; Collagen; Female; Humans; Inflammation; Mice; Neutrophils; Nicotiana; Prolyl Oligopeptidase | 2014 |
Safety of valproic acid in patients with chronic obstructive pulmonary disease: a population-based cohort study.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Cohort Studies; Female; Hospitalization; Humans; Male; Pop | 2015 |
Histone deacetylase activity and COPD.
Topics: Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Histone Deacetylase 2; Histone Deacetyla | 2005 |