valproic acid has been researched along with African Lymphoma in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Burkitt lymphoma is a highly aggressive B-cell neoplasm." | 5.42 | Valproic Acid Enhances the Anti-tumor Effect of (-)-gossypol to Burkitt Lymphoma Namalwa Cells. ( Chen, XH; Gong, Y; Ni, ZH; Zhang, X; Zou, ZM, 2015) |
| " We found that 4 histone deacetylase inhibitors, trichostatin A (TSA), sodium butyrate (SB), valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA), all significantly induced EBV lytic cycle in EBV-positive gastric carcinoma cells (AGS/BX1, latency II) but only weakly induced in Burkitt lymphoma cells (AK2003, latency I) and did not induce in lymphoblastoid cells (LCLs, latency III)." | 3.76 | Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein-Barr virus-positive epithelial malignancies and mediates enhanced cell death. ( Chiang, AK; Hui, KF, 2010) |
| "Burkitt lymphoma is a highly aggressive B-cell neoplasm." | 1.42 | Valproic Acid Enhances the Anti-tumor Effect of (-)-gossypol to Burkitt Lymphoma Namalwa Cells. ( Chen, XH; Gong, Y; Ni, ZH; Zhang, X; Zou, ZM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, LH | 1 |
| Cheng, S | 1 |
| Zheng, Z | 1 |
| Wang, L | 1 |
| Shen, Y | 1 |
| Shen, ZX | 1 |
| Chen, SJ | 1 |
| Zhao, WL | 1 |
| Gong, Y | 1 |
| Ni, ZH | 1 |
| Zhang, X | 1 |
| Chen, XH | 1 |
| Zou, ZM | 1 |
| Hui, KF | 1 |
| Chiang, AK | 1 |
| Tsapis, M | 1 |
| Lieb, M | 1 |
| Manzo, F | 1 |
| Shankaranarayanan, P | 1 |
| Herbrecht, R | 1 |
| Lutz, P | 1 |
| Gronemeyer, H | 1 |
4 other studies available for valproic acid and African Lymphoma
| Article | Year |
|---|---|
Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Burkitt Lymphoma; Cell Line, Tum | 2013 |
Valproic Acid Enhances the Anti-tumor Effect of (-)-gossypol to Burkitt Lymphoma Namalwa Cells.
Topics: Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Contraceptive Agents, Male; Dr | 2015 |
Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein-Barr virus-positive epithelial malignancies and mediates enhanced cell death.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Burkitt Lymphoma; Butyrates; Carcinoma; Cell Cy | 2010 |
HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway.
Topics: Apoptosis; Benzamides; Burkitt Lymphoma; Cyclin-Dependent Kinase Inhibitor p21; Dexamethasone; Drug | 2007 |