valproic acid has been researched along with Afibrinogenemia in 12 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Afibrinogenemia: A deficiency or absence of FIBRINOGEN in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following surgery, he routinely received valproic acid (VPA) to prevent seizures." | 4.89 | Valproic acid-associated low fibrinogen and delayed intracranial hemorrhage: case report and mini literature review. ( Chen, HF; Cui, QY; Jin, LJ; Li, ZY; Luo, ZY; Qin, LM; Ren, YY; Shen, HS; Tang, JQ; Wang, J; Wang, KY; Wang, ZY; Wu, TQ; Xu, LP; Yu, ZQ; Zhu, JJ, 2013) |
| "Chemotherapy with a combination of synthetic ACTH (ACTH-Zn) and valproic acid (VPA) induced remarkable hypofibrinogenemia in three children (5 months, 8 months, and 5 years and 10 months old) with intractable epilepsy." | 3.69 | [Three cases of hypofibrinogenemia induced by chemotherapy with a combination of synthetic ACTH and valproic acid]. ( Kodani, N; Ogino, T; Tokuda, K, 1994) |
| "Three patients with dysfibrinogenemia or fibrinogen deficiency showed normal or slightly prolonged PT values and normal APTT values." | 1.34 | [Analysis of hypofibrinogenemias found on routine coagulation screening tests and identification of heterozygous dysfibrinogenemia or fibrinogen deficiency]. ( Fujihara, N; Hirota-Kawadobora, M; Ishikawa, S; Kamijo, Y; Katsuyama, T; Okumura, N; Terasawa, F; Wakabayashi, S; Yamauchi, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, R | 1 |
| Wang, Q | 1 |
| Zhou, Y | 1 |
| Shi, W | 1 |
| Zhang, Y | 1 |
| Wang, M | 1 |
| Li, H | 1 |
| Zhao, R | 1 |
| Chen, HF | 2 |
| Xu, LP | 1 |
| Luo, ZY | 1 |
| Yu, ZQ | 1 |
| Li, ZY | 2 |
| Cui, QY | 1 |
| Qin, LM | 1 |
| Ren, YY | 1 |
| Shen, HS | 1 |
| Tang, JQ | 2 |
| Jin, LJ | 1 |
| Zhu, JJ | 1 |
| Wang, J | 1 |
| Wang, KY | 1 |
| Wu, TQ | 1 |
| Wang, ZY | 1 |
| Hirota-Kawadobora, M | 1 |
| Ishikawa, S | 1 |
| Fujihara, N | 1 |
| Wakabayashi, S | 1 |
| Kamijo, Y | 1 |
| Yamauchi, K | 1 |
| Terasawa, F | 1 |
| Okumura, N | 1 |
| Katsuyama, T | 1 |
| Bavoux, F | 1 |
| Fournier-Perhilou, AI | 1 |
| Wood, C | 1 |
| Francoual, C | 1 |
| Boccara, JF | 1 |
| Tokuda, K | 1 |
| Kodani, N | 1 |
| Ogino, T | 1 |
| Breningstall, GN | 1 |
| Cich, JA | 1 |
| Dale, BM | 1 |
| Purdie, GH | 1 |
| Rischbieth, RH | 1 |
| Nutt, JG | 1 |
| Neophytides, AN | 1 |
| Lodish, JR | 1 |
| Hutchinson, RM | 1 |
| Clay, CM | 1 |
| Simpson, MR | 1 |
| Wood, JK | 1 |
| Majer, RV | 1 |
| Green, PJ | 1 |
| Coquerel, A | 1 |
| Senant, J | 1 |
| Samson, M | 1 |
| Sauger, F | 1 |
| Samson-Dollfus, D | 1 |
| Parain, D | 1 |
| Leroy, A | 1 |
| Hue, G | 1 |
| Borg, JY | 1 |
| Matray, F | 1 |
1 review available for valproic acid and Afibrinogenemia
| Article | Year |
|---|---|
Valproic acid-associated low fibrinogen and delayed intracranial hemorrhage: case report and mini literature review.
Topics: Adult; Afibrinogenemia; Anticonvulsants; Cerebral Hemorrhage; Humans; Male; Seizures; Time Factors; | 2013 |
11 other studies available for valproic acid and Afibrinogenemia
| Article | Year |
|---|---|
The prevalence and risk factors of coagulopathy in pediatric patients undergoing surgery for epilepsy.
Topics: Afibrinogenemia; Anticonvulsants; Blood Coagulation Disorders; Body Weight; Child; Epilepsy; Humans; | 2023 |
[Hypofibrinogenemia and intracranial hemorrhage induced by valproic acid: a case report].
Topics: Adult; Afibrinogenemia; Humans; Intracranial Hemorrhages; Male; Valproic Acid | 2012 |
[Analysis of hypofibrinogenemias found on routine coagulation screening tests and identification of heterozygous dysfibrinogenemia or fibrinogen deficiency].
Topics: Adrenocorticotropic Hormone; Afibrinogenemia; Asparaginase; Fibrinogen; Heterozygote; Humans; Infant | 2007 |
Neonatal fibrinogen depletion caused by sodium valproate.
Topics: Afibrinogenemia; Epilepsy; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Pregnancy | 1994 |
[Three cases of hypofibrinogenemia induced by chemotherapy with a combination of synthetic ACTH and valproic acid].
Topics: Adrenocorticotropic Hormone; Afibrinogenemia; Child, Preschool; Drug Therapy, Combination; Epilepsy; | 1994 |
Pseudo valproate-induced hypofibrinogenemia.
Topics: Afibrinogenemia; Anticonvulsants; Child; Fibrinogen; Humans; Male; Valproic Acid | 1996 |
Fibrinogen depletion with sodium valproate.
Topics: Adolescent; Afibrinogenemia; Humans; Platelet Aggregation; Valerates; Valproic Acid | 1978 |
Lowered erythrocyte-sedimentation rate with sodium valproate.
Topics: Adult; Afibrinogenemia; Blood Sedimentation; Fibrinogen; Humans; Movement Disorders; Valproic Acid | 1978 |
Lowered erythrocyte-sedimentation rate with sodium valproate.
Topics: Afibrinogenemia; Blood Sedimentation; Epilepsy; Humans; Valproic Acid | 1978 |
Neonatal afibrinogenaemia due to sodium valproate.
Topics: Afibrinogenemia; Female; Fibrinogen; Humans; Infant, Newborn; Male; Valproic Acid | 1987 |
[Incidence of hypofibrinogenemia under valproate. Could it allow the detection of hepatotoxicity of this drug?].
Topics: Afibrinogenemia; Chemical and Drug Induced Liver Injury; Humans; Valproic Acid | 1986 |