valproic acid has been researched along with Adult Rickets in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid (VPA) is a wide spread anticonvulsant and mood-stabilizing agent, the use of which is associated with hepatotoxicity, bone marrow suppression and osteomalacia." | 7.77 | Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia? ( Bachleda, P; Bitman, M; Doricakova, A; Dvorak, Z; Novotna, A; Pavek, P; Vrzal, R, 2011) |
| "Valproic acid (VPA) is a wide spread anticonvulsant and mood-stabilizing agent, the use of which is associated with hepatotoxicity, bone marrow suppression and osteomalacia." | 3.77 | Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia? ( Bachleda, P; Bitman, M; Doricakova, A; Dvorak, Z; Novotna, A; Pavek, P; Vrzal, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vrzal, R | 1 |
| Doricakova, A | 1 |
| Novotna, A | 1 |
| Bachleda, P | 1 |
| Bitman, M | 1 |
| Pavek, P | 1 |
| Dvorak, Z | 1 |
| Tillmann, F | 1 |
| Kruppa, E | 1 |
| Grün, R | 1 |
| Blaschke, S | 1 |
| Delling, G | 1 |
| Karaaslan, Y | 1 |
| Haznedaroğlu, S | 1 |
| Oztürk, M | 1 |
| Pedrera, JD | 1 |
| Canal, ML | 1 |
| Carvajal, J | 1 |
| Postigo, S | 1 |
| Villa, LF | 1 |
| Hernández, ER | 1 |
| Rico, H | 1 |
1 trial available for valproic acid and Adult Rickets
| Article | Year |
|---|---|
Influence of vitamin D administration on bone ultrasound measurements in patients on anticonvulsant therapy.
Topics: 25-Hydroxyvitamin D 2; Adult; Aged; Anticonvulsants; Bone and Bones; Calcifediol; Carbamazepine; Epi | 2000 |
3 other studies available for valproic acid and Adult Rickets
| Article | Year |
|---|---|
Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia?
Topics: Anticonvulsants; Blotting, Western; Cholecalciferol; Dose-Response Relationship, Drug; Extracellular | 2011 |
[Increased fracture risk in a 67-year-old patient with hypocalcemia of unknown etiology].
Topics: Aged; Anticonvulsants; Biopsy; Bone and Bones; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Fe | 1999 |
Osteomalacia associated with carbamazepine/valproate.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Osteomalacia; Valproic Acid | 2000 |